Results 161 to 170 of about 706,792 (383)

Probing the nature of interactions in SH2 binding interfaces–evidence from electrospray ionization mass spectrometry [PDF]

, 1999
Evonne W. Chung, Denise Y. P. Henriques, Debora Renzoni, Craig J. Morton, Terrence D. Mulhern, Maureen Pitkeathly, John E. Ladbury, Carol V. Robinson   +7 more
openalex   +1 more source

Minimally Invasive Chemical Biopsy Needle with Self‐Wettable Extraction Phase For In Vivo Tissue Sampling During Medical Procedures

Advanced Science, EarlyView.
A new tissue sampling device using an acupuncture needle with bio‐compatible extraction sorbents in the recessed section is developed. The coating material using self‐wettable particles doesn't require solvent activation after sterilization. This device is applied for the anti‐cancer drug concentration monitoring during the in vivo lung perfusion ...
Runshan Will Jiang, Wei Zhou, Marcelo Cypel, Todd L. Demmy, Gal Shafirstein, Guillermo Garza, Emily Gawrys, Joanna Bogusiewicz, Barbara Bojko, Janusz Pawliszyn   +9 more
wiley   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

Analysis of Oligonucleotides by Electrospray Ionization Mass Spectrometry [PDF]

, 2000
Lenore M. Polo, Patrick A. Limbach
openalex   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Isolation and characterization of protoporphyrin glycoconjugates from rat Harderian gland by HPLC, capillary electrophoresis and HPLC/electrospray ionization MS [PDF]

, 2000
Chang Kee Lim, M. Aaqib RAZZAQUE, Jinli Luo, Peter B. Farmer   +3 more
openalex   +1 more source

Crystalline‐Amorphous Heterostructure: A Novel Configuration for Silver Nanoclusters

Advanced Science, EarlyView.
This study presents a spontaneously formed amorphous‐crystalline heterostructure composite composed of atomically precise carboranylthiolate‐protected silver NCs, demonstrating not only a unique co‐assembly of distinct metal NCs at the macroscopic level but also promising potential applications of metal cluster‐based materials.
Jia‐Hong Huang, Yao Cui, Peng Luo, Zhao‐Yang Wang, Shuang‐Quan Zang   +4 more
wiley   +1 more source

Method validation of clonidine hydrochloride in human plasma by LC-MS technique

Pharmaceutical and Biomedical Research, 2015
A simple and sensitive high performance liquid chromatography-electrospray ionization mass spectrometry method has been evaluated for the assignment of clonidine hydrochloride in human plasma.
Hossein Danafar
doaj  

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang, Shengtao Cheng, Huiying Gu, Shan Zhong, Dapeng Zhang, Xin He, Weixian Chen, Haijun Deng, Jihua Ren, Peng Chen, Ming Tan, Hui Zhang, Fan Li, Zhenzhen Zhang, Yuan Hu, Juan Chen   +15 more
wiley   +1 more source

Increased Glutathionyl Hemoglobin in Diabetes Mellitus and Hyperlipidemia Demonstrated by Liquid Chromatography/Electrospray Ionization-Mass Spectrometry [PDF]

, 2000
Toshimitsu Niwa, Chika Naito, Abdul Hassan Mohammed Mawjood, Kiyohiro Imai   +3 more
openalex   +1 more source