Probing metal ion binding and conformational properties of the colicin E9 endonuclease by electrospray ionization time-of-flight mass spectrometry [PDF]
Nano-electrospray ionization time-of-flight mass spectrometry (ESI-MS) was used to study the conformational consequences of metal ion binding to the colicin E9 endonuclease (E9 DNase) by taking advantage of the unique capability of ESI-MS to allow ...
HECK, ALBERT J.R.+6 more
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Liquid chromatography-tandem mass spectrometry - Application in the clinical laboratory [PDF]
This review provides a concise survey of liquid chromatography tandem mass spectrometry (LCTMS) as an emerging technology in clinical chemistry. The combination of two mass spectrometers with an interposed collision cell characterizes LCTMS as an ...
Ford RE+7 more
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Is Charge Reduction in ESI Really Necessary? [PDF]
The technique of charge reduction electrospray mass spectrometry (CREMS), which can reduce the charge state complexity produced in electrospray ionization (ESI), is ...
Smith, Lloyd M.
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Matrix effect in bio-analysis of illicit drugs with LC-MS/MS: Influence of ionization type, sample preparation, and biofluid [PDF]
The purpose of the present work was to evaluate the synergistic effect of ionization type, sample preparation technique, and bio-fluid on the presence of matrix effect in quantitative liquid chromatography (LC)-MS/MS analysis of illicit drugs by post ...
Dams, Riet+3 more
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Evaporation and Discharge Dynamics of Highly Charged Multicomponent Droplets Generated by Electrospray Ionization [PDF]
We investigate the Rayleigh discharge and evaporation dynamics of highly charged two-component droplets consisting principally of methanol with 2-methoxyethanol, tert-butanol, or m-nitrobenzyl alcohol.
Beauchamp, J. L., Grimm, Ronald L.
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Neutral particle Mass Spectrometry with Nanomechanical Systems [PDF]
Current approaches to Mass Spectrometry (MS) require ionization of the analytes of interest. For high-mass species, the resulting charge state distribution can be complex and difficult to interpret correctly.
Alava, Thomas+9 more
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Degrees of freedom effect on fragmentation in tandem mass spectrometry of singly charged supramolecular aggregates of sodium sulfonates [PDF]
The characteristic collision energy (CCE) to obtain 50% fragmentation of positively and negatively single charged non-covalent clusters has been measured.
Bongiorno, David+7 more
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Single-photon absorption of isolated collagen mimetic peptides and triple-helix models in the VUV-X energy range [PDF]
Cartilage and tendons owe their special mechanical properties to the fibrous collagen structure. These strong fibrils are aggregates of a sub-unit consisting of three collagen proteins wound around each other in a triple helix.
Eden, Samuel+9 more
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Current developments in LC-MS for pharmaceutical analysis [PDF]
The current developments in liquid chromatography-mass spectrometry (LC-MS) and its applications to the analysis of pharmaceuticals are reviewed. Various mass spectrometric techniques, including electrospray and nanospray ionization, atmospheric pressure
Lim, Chang-Kee, Lord, Gwyn A.
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Transformation of neutral rhenium compounds during electrospray ionization mass spectrometry [PDF]
Four neutral rhenium compounds were examined by electrospray ionization mass spectrometry. Acetonitrile solutions of (Ind)Re(CO)3 (Ind = indenyl) and (Cp)Re(CO)3 (Cp = cyclopentadienyl) gave rise to [Re(CO)3(CH3CN)3]+ ions.
Bakhtiar, R.+2 more
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