Results 191 to 200 of about 119,736 (261)

Ion Activation Methods for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Plasma Glucosylsphingosine in GBA1 E365K, N409S, and L483P Heterozygous Mutation Carriers

open access: yesMovement Disorders, EarlyView.
Abstract Background GBA1 encodes the lysosomal enzyme glucocerebrosidase, with key substrates that include glucosylceramide and glucosylsphingosine. The E365K variant is the most common variant in GBA1 that is associated with Parkinson's disease (PD) but is not associated with Gaucher disease.
Julian Agin‐Liebes   +7 more
wiley   +1 more source

Charging of DNA Complexes in Positive-Mode Native Electrospray Ionization Mass Spectrometry. [PDF]

open access: yesJ Am Soc Mass Spectrom
Abramsson ML   +4 more
europepmc   +1 more source

Detection of IDH mutation in glioma by desorption electrospray ionization (DESI) tandem mass spectrometry. [PDF]

open access: yesSci Rep
Shahi M   +5 more
europepmc   +1 more source

Quantification of Homopolymer Impurities in Structured Acrylate Copolymers Produced by High‐Temperature Semi‐Batch Radical Polymerization

open access: yesMacromolecular Reaction Engineering, EarlyView.
Isobornyl acrylate macromonomer solutions are synthesized via high‐temperature radical polymerization using a starved‐feed semi‐batch operating policy. Through sequential feeding, the macromonomer solution functions as an addition‐fragmentation agent, facilitating the production of blocky and comb acrylate copolymers.
Elizabeth G. Bygott   +3 more
wiley   +1 more source

Characterization of Anticancer Drug Protomers Using Electrospray Ionization and Ion Mobility Spectrometry-Mass Spectrometry. [PDF]

open access: yesJ Am Soc Mass Spectrom
Basuri P   +6 more
europepmc   +1 more source

Exploration of the Phytochemical and Antidiabetic Properties of Teucrium polium: A Natural Asset for Type 2 Diabetes Management

open access: yesChemistryOpen, EarlyView.
Teucrium polium shows antidiabetic activity with its phytochemical composition and biological activities. The essential oil is rich in carvacrol, thymol, γ‐terpinene, and o‐cymene, while the aqueous and hydroethanolic extracts are characterized by poliumoside, verbascoside, isorhamnetin‐3‐O‐rutinoside, and apigenin‐7‐rutinoside. Antioxidant activity is
Hajar El Ouadni   +10 more
wiley   +1 more source

Computational Study on Potentially Active Antibacterial Compounds in Secondary Metabolites of Extremophilic Microorganisms

open access: yesChemistryOpen, EarlyView.
This study employed density functional theory (DFT) and conceptual DFT (CDFT) to calculate the structures and properties of potential antibacterial compounds derived from 16‐membered lactone ring‐containing secondary metabolites of extremophiles, as well as midecamycin.
Dilong Li   +6 more
wiley   +1 more source

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