Results 201 to 210 of about 718,278 (381)

A Hexadecacationic Metal–Organic Cage for Anchoring Sulfonates: High‐Order Binding of Di‐ and Trisulfonates and High‐Performance Removal of Perfluorosulfonates from Water

open access: yesAdvanced Science, EarlyView.
Developing synthetic hosts that can bind sulfonate anions or sequester perfluorosulfonates is crucial in biological and environmental sciences. Here, a Zr‐based metal–organic cage (1) integrating electron‐deficient tripyridinium panels is designed and synthesized.
Yawei Liu   +8 more
wiley   +1 more source

Lipid and metabolite profiles of human brain tumors by desorption electrospray ionization-MS

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2016
A. Jarmusch   +5 more
semanticscholar   +1 more source

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu   +8 more
wiley   +1 more source

Lipidomic profiling of endometrial cancer using desorption electrospray ionization mass spectrometry imaging. [PDF]

open access: yesProc Natl Acad Sci U S A
Paraskevaidi M   +14 more
europepmc   +1 more source

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

open access: yesAdvanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun   +9 more
wiley   +1 more source

Innovative Application of a Multifunctional Sucrose-Gelatin Hydrogel Matrix in Desorption Electrospray Ionization-Mass Spectrometry Imaging. [PDF]

open access: yesAnal Chem
Ziaco M   +17 more
europepmc   +1 more source

Development of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins

open access: yesAdvanced Science, EarlyView.
Development of oligoglycine‐based dimethylsulfonium probes for unbiased crosslinking to methyllysine readers. The general probe facilitates profiling of site‐specific methyllysine readers, evaluation of selectivity and activity of reader inhibitors, and global profiling of methyllysine readers.
Jinyu Yang   +3 more
wiley   +1 more source

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