Results 51 to 60 of about 142,148 (337)

Overcharging Effect in Electrospray Ionization Mass Spectra of Daunomycin-Tuftsin Bioconjugates

Molecules, 2019
Peptide-based small molecule drug conjugates for targeted tumor therapy are currently in the focus of intensive research. Anthracyclines, like daunomycin, are commonly used anticancer drug molecules and are also often applied in peptide-drug conjugates ...
Lilla Pethő, Gábor Mező, Gitta Schlosser   +2 more
doaj   +1 more source

How Soft Is Secondary Electrospray Ionization?

Journal of the American Society for Mass Spectrometry, 2022
ISSN:1044 ...
Jérôme Kaeslin, Cedric Wüthrich, Stamatios Giannoukos, Renato Zenobi   +3 more
openaire   +3 more sources

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

About the Electrospray Ionization Source in Mass Spectrometry: Electrochemistry and On-chip Reactions

CHIMIA, 2009
The present work shows that the electrochemical properties of electrospray ionization (ESI) can be used to add functions to the process. As example, we show how the choice of the electrode material can be used to study interactions between metal
Michel Prudent, Manuel Méndez, Christophe Roussel, Bin Su, Niels Lion, Joël S. Rossier, Hubert H. Girault   +6 more
doaj   +1 more source

Studying the Complexity of Biomass Derived Biofuels

Energies, 2021
Biofuel produced from biomass pyrolysis is a good example of a highly complex mixture. Detailed understanding of its composition is a prerequisite for optimizing transformation processes and further upgrading conditions.
Yun Xu, Wolfgang Schrader
doaj   +1 more source

Kinetic Control of Protonation in Electrospray Ionization [PDF]

Journal of the American Society for Mass Spectrometry, 2011
The site of protonation in a molecule can greatly affect the fragments observed in product ion MS/MS spectra. In electrospray positive ionization mass spectra, protonation usually occurs predominantly on the most basic site on the molecule to produce the thermodynamically favored protonated species.
J. Richard Joyce, Don S. Richards
openaire   +3 more sources

Investigating the Structure–Function Relationships of Fluorinated Interfaces for PFAS Capture and Electrochemically‐Mediated Release

Advanced Functional Materials, EarlyView.
This study explores the use of fluorinated copolymers with varying fluorophilic side chain lengths to enhance PFAS affinity. The integration of electrochemical techniques demonstrates enhanced adsorbent regeneration, with molecular dynamics simulations providing insight into the molecular‐level interactions involved.
Anaira Román Santiago, Adrija Dutta, Jhen‐Cih Wu, Song Yin, Ye Won Lee, Chia‐Hung Hou, Diwakar Shukla, Xiao Su   +7 more
wiley   +1 more source

Present status of theoretical understanding of charge changing processes at low beam energies [PDF]

, 2017
A model for the evaluation of charge-state distributions of fast heavy ions in solid targets is being developed since late eighties in terms of ETACHA code. Time to time it is being updated to deal with more number of electrons and non-perturbative processes.
arxiv   +1 more source

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

Advanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen, Andreas B. Pedersen, Mireia Casanovas Montasell, Søren Moesgaard, Anja Bille Bohn, Alexander N. Zelikin   +5 more
wiley   +1 more source

Electrospray Ionization Mass Spectrometric Analysis of Highly Reactive Glycosyl Halides

Molecules, 2012
Highly reactive glycosyl chlorides and bromides have been analysed by a routine mass spectrometric method using electrospray ionization and lithium salt adduct-forming agents in anhydrous acetonitrile solution, providing salient lithiated molecular ions [
Lajos Kovács, János Szolomájer, Tünde Zita Illyés, Zoltán Kele, Attila Bokros, Annamária Bánfi, Zoltán Kupihár   +6 more
doaj   +1 more source