Results 121 to 130 of about 297,282 (382)

Water‐Mediated 1,7‐Palladium Aryl‐to‐Aryl Migration in an Unusual Aryne Trimerization Enables the Synthesis of Multihelicenes with Profoundly Hindered Stereogenic Axes

Advanced Synthesis &Catalysis, EarlyView.
In the presence of a Pd0 catalyst, large π‐extended arynes trimerize in an unusual manner to forge extremely compact and strained chiral benzenoids. This new trimerization reaction involves a 1,7‐Pd isomerization, a rare and poorly understood process that is elucidated.
Albert Artigas, Manuel A. Ortuño, Jesús Castro‐Esteban, Michel Giorgi, Diego Peña, Dolores Pérez, Yoann Coquerel   +6 more
wiley   +1 more source

Quantification of seminolipid by LC-ESI-MS/MS-multiple reaction monitoring: compensatory levels in Cgt mice[S]

Journal of Lipid Research, 2010
Seminolipid, also known as sulfogalactosylglycerolipid (SGG), plays important roles in male reproduction. Therefore, an accurate and sensitive method for SGG quantification in testes and sperm is needed.
Kessiri Kongmanas, Hongbin Xu, Arman Yaghoubian, Laura Franchini, Luigi Panza, Fiamma Ronchetti, Kym Faull, Nongnuj Tanphaichitr   +7 more
doaj   +1 more source

The search for exudates from Eurasian watermilfoil and hydrilla [PDF]

, 2002
Secondary metabolites are produced by aquatic plants, and in some instances, exudation of these metabolites into the surrounding water has been detected.
Glomski, Lee Ann M., Lembi, C.A., Nicholson, R.L., Wood, K.V.   +3 more
core  

Electronic Spectroscopy of Isolated DNA Polyanions

, 2018
In solution, UV-vis spectroscopy is often used to investigate structural changes in biomolecules (i.e., nucleic acids), owing to changes in the environment of their chromophores (i.e., the nucleobases).
Daly, Steven, Gabelica, Valérie, Porrini, Massimiliano, Rosu, Frederic   +3 more
core   +2 more sources

Rapid deconvolution of low-resolution time-of-flight data using Bayesian inference [PDF]

, 2019
The deconvolution of low-resolution time-of-flight data has numerous advantages, including the ability to extract additional information from the experimental data.
Bernardo J. M., Cornelius L. Pieterse, Hans C. Eggers, Mamyrin B. A., Michiel B. de Kock, Press W. H., R. J. Dwayne Miller, Wesley D. Robertson   +7 more
core   +2 more sources

Photoredox‐Catalyzed Synthesis of a Novel Class of Fluoroalkyl Pyrazolones

Advanced Synthesis &Catalysis, EarlyView.
A photoredox strategy enables regioselective synthesis of fluoroalkyl 2‐pyrazolin‐5‐ones via radical addition and cyclization. This mild, metal‐free method shows a broad substrate scope, operates in batch and flow systems, and offers a sustainable approach to fluorinated heterocycles with potential applications in medicinal chemistry.
Emanuele F. Pissinati, Meysam Azizzade, Till Opatz, Márcio W. Paixão   +3 more
wiley   +1 more source

Metabolite fingerprinting by infrared matrix-assisted laser desorption electrospray ionization mass spectrometry

SLAS Technology
The adoption of mass spectrometry for high-throughput screening in drug discovery has become increasingly prevalent and has enabled label-free screening against diverse targets.
Alena N. Joignant, Fan Pu, Shaun M. McLoughlin, James W. Sawicki, Andrew J. Radosevich, Renze Ma, Jon D. Williams, Sujatha M. Gopalakrishnan, Nathaniel L. Elsen   +8 more
doaj   +1 more source

Liquid chromatography-tandem mass spectrometry - Application in the clinical laboratory [PDF]

, 2003
This review provides a concise survey of liquid chromatography tandem mass spectrometry (LCTMS) as an emerging technology in clinical chemistry. The combination of two mass spectrometers with an interposed collision cell characterizes LCTMS as an ...
Ford RE, Kushnir MM, Kushnir MM, Muck W, Murdter TE, Rashed MS, Streit F, Taylor RL   +7 more
core   +1 more source

Naphthalimide Derivatives as Film‐Based Fluorescent Sensors for Rapid Detection of Illicit Drugs

Advanced Sensor Research, EarlyView.
Four novel 1,8‐naphthalimide (NI) derivatives for the detection of illicit drugs with different substituents at the 4‐position are reported. Their contrasting fluorescence responses enables five illicit drugs to be distinguished from interferents with a mean classification accuracy of 81%.
Ming Chen, Harrison Stitt, Ronan Chu, Jos C. M. Kistemaker, Ian A. Wood, Paul L. Burn, Ian R. Gentle, Paul E. Shaw   +7 more
wiley   +1 more source

Three-Dimensional-Printed Lateral Extraction Enhanced Desorption Electrospray Ionization Source for Mass Spectrometry

Applied Sciences
This paper introduces a novel Lateral Extraction Enhanced Desorption Electrospray Ionization (LEE-DESI) source. This source is specifically designed to tackle the crucial issue of electric field interference in dual-channel ambient ionization mass ...
Jilin Liu, Xiang Qian
doaj   +1 more source