Results 151 to 160 of about 201,447 (356)
Advanced Science, EarlyView.Esophageal squamous cell carcinoma urgently requires new therapeutic strategies. Adenosine diphosphate‐ribosylation factor‐like protein 5B (ARL5B) is identified as a novel oncogene that remodels fatty acid metabolism through the ras homologous‐associated coiled‐coil containing protein kinase 1 (ROCK1)–sterol regulatory element‐binding protein 1 (SREBP1)
Xinyue Ma +12 more
wiley +1 more source
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
Advanced Science, EarlyView.The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
Nanospray desorption electrospray ionization mass spectrometry of untreated and treated probiotic Lactobacillus reuteri cells [PDF]
, 2018 Agbo-Oma Uwakweh +4 more
openalex +1 more source
Advanced Science, EarlyView.EGFR mutations drive ERK/c‐Jun–mediated transcriptional activation of CD73, elevating adenosine levels and fostering an immunosuppressive TME by impairing DC maturation and CD8⁺ T cell priming. The pH‐responsive nanodrug F127ZIF‐8AB680 selectively inhibits CD73, normalizes adenosine metabolism, and re‐establishes effective anti‐tumor immunity ...
Xiaoling Shang +14 more
wiley +1 more source
Desorption Electrospray Ionization Mass Spectrometry: 20 Years. [PDF]
Acc Chem Res, 2023 Morato NM, Cooks RG.
europepmc +1 more source
PCR Followed by Electrospray Ionization Mass Spectrometry for Broad-Range Identification of Fungal Pathogens [PDF]
, 2013 Christian Massire +14 more
openalex +1 more source
Advanced Science, EarlyView.This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong +15 more
wiley +1 more source
Liquid Chromatography/Electrospray Ionization/Isotopic Dilution Mass Spectrometry Analysis of n-(Phosphonomethyl) Glycine and Mass Spectrometry Analysis of Aminomethyl Phosphonic Acid in Environmental Water and Vegetation Matrixes [PDF]
, 2001 Lorna Grey, Bick Nguyen, Paul Yang
openalex +1 more source