Results 151 to 160 of about 195,406 (308)

Isomer Composition Assessment of Synthetic Phosphatidylethanol by Collision‐Induced and Ozone‐Induced Dissociation Mass Spectrometry

Drug Testing and Analysis, EarlyView.
This study examines the isomeric composition of PEth reference materials and compares it with the natural variation in isomer distribution found in blood samples. ABSTRACT The direct blood‐alcohol biomarker phosphatidylethanol (PEth), especially its most abundant analogue 1‐palmitoyl‐2‐oleoyl‐sn‐phosphatidylethanol (PEth 16:0/18:1) has gained ...
Matthias Bantle, Jackson O. T. Long, Samuel C. Brydon, Reuben S. E. Young, Stephen J. Blanksby, Wolfgang Weinmann, Marc Luginbühl   +6 more
wiley   +1 more source

Bioactivation and Metabolism of Amino Acid MDMA Prodrugs in Zebrafish Embryos, Human Liver S9, Whole Blood, and Microdosed Human Urine

Drug Testing and Analysis, EarlyView.
Bioactivation and metabolism of MDMA prodrugs: MDMA‐Trp, MDMA‐Lys, MDMA‐Gly showed unique urine screening targets only for MDMA‐Trp, while biomarkers for MDMA‐Lys and MDMA‐Gly consisted of MDMA and known MDMA metabolites. Conversion of amino acid prodrugs to MDMA in pHLS9, zebrafish embryos, and humans. ABSTRACT 3,4‐Methylenedioxymethamphetamine (MDMA)
Simon K. Wellenberg, Lea Wagmann, Matthias D. Kroesen, Philip Schippers, Matthias Grill, Jennifer Herrmann, Markus R. Meyer   +6 more
wiley   +1 more source

Evaluation of Different Detection and Identification Methods of Intact Tetrahydro‐Methyltestosterone Sulfate Metabolites in Doping Control

Drug Testing and Analysis, EarlyView.
The micro‐scale synthesis of the six out of eight possible tetrahydro‐methyltestosterone sulfate metabolites was performed, and the synthesized materials were used as analytical standards. The analysis of post‐administration sample extracts from methyltestosterone excretion studies against these standards provides further experimental proof for their ...
Yiannis S. Angelis, Olga Goula, Polyxeni Kiousi, Panagiotis Sakellariou   +3 more
wiley   +1 more source

Negative Gaseous Ions in Positive-Voltage Electrospray Ionization Mass Spectrometry. [PDF]

Anal Chem
Wang XB, Ochirov O, Ke BC, Abu Bakar NH, Raju CM, Marginean I, Urban PL.   +6 more
europepmc   +1 more source

Enantioselective Determination of Amphetamine‐Type Stimulants in Environmental Waters Using SPE and CE–MS/MS

ELECTROPHORESIS, EarlyView.
ABSTRACT The growing concern over drug abuse, particularly involving amphetamine‐type substances (ATS), has led to their monitoring in environmental waters. These chiral compounds, commonly found in river water and wastewater treatment plant (WWTP) effluents, require analytical methods capable of enantiomeric discrimination, as their enantiomers can ...
Pol Clivillé‐Cabré, Francesc Borrull, Carme Aguilar, Marta Calull   +3 more
wiley   +1 more source

Lipidomic profiling of endometrial cancer using desorption electrospray ionization mass spectrometry imaging. [PDF]

Proc Natl Acad Sci U S A
Paraskevaidi M, Raglan O, McKenzie J, Xiang Y, Maneta-Stavrakaki S, Doria ML, Galani A, Assi N, Manoli E, Ellis LB, Kaur B, Rosini F, Gunter MJ, Takats Z, Kyrgiou M.   +14 more
europepmc   +1 more source

Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra‐Targeted Tumor α‐Therapy

Exploration, EarlyView.
Encapsulating 223Ra in Au10‐12 nanoclusters and functionalizing them with RGD peptides enables targeted α‐therapy and immune microenvironment remodeling in non‐osseous tumors like triple‐negative breast cancer. This study establishes a foundational framework for novel 223Ra‐labeled α‐radiopharmaceuticals and shows strong potential for clinical ...
Yifei Jiang, Huizhen Yang, Guoping Jia, Wangxi Hai, Rongyi Huang, Peng Wang, Min Zhang, Danni Li, Yizhou Chen, Xiao Li, Biao Li, Chunfu Zhang   +11 more
wiley   +1 more source

Innovative Application of a Multifunctional Sucrose-Gelatin Hydrogel Matrix in Desorption Electrospray Ionization-Mass Spectrometry Imaging. [PDF]

Anal Chem
Ziaco M, Vitale GA, Barra G, Marfella B, dell'Isola M, Albiani F, Grazioso A, Giamundo G, Nuzzo G, Manzo E, Gallo C, Castiglia D, Verrillo L, Miano MG, Cristino L, Conte I, d'Ippolito G, Fontana A.   +17 more
europepmc   +1 more source

Physicochemical Properties and Antioxidant Activity of Apocynum Honey in Different Regions of Xinjiang

Food Chemistry International, EarlyView.
ABSTRACT In this study, honey produced from Apocynum venetum L. was collected from BC (Bachu County), SY (Shaya County), and YL (Yuli County) in Xinjiang. The basic physical and chemical properties of the honey, and the contents of total phenols, total flavonoids, and amino acids were analyzed, and 16 types of polyphenols were quantified using triple ...
Na Zhang, Jingjing Lv, Ruili Zhang, Qinghua Jia, Tiantian Jian, Yawen Li   +5 more
wiley   +1 more source

Extractive Electrospray Ionization Mass Spectrometry for Rapid Analysis of Organic and Inorganic Selenium in Honey. [PDF]

Molecules
Zhang X, Qiu Y, Xing H, Yang F, Zeng P, Fan H, Chen H, Fang X.   +7 more
europepmc   +1 more source