Results 61 to 70 of about 439,053 (379)

Distinct conformational stability and functional activity of four highly homologous endonuclease colicins [PDF]

open access: yes, 2004
The family of conserved colicin DNases E2, E7, E8, and E9 are microbial toxins that kill bacteria through random degradation of the chromosomal DNA.
Bowman   +43 more
core   +2 more sources

Cerebrospinal fluid, neuroinflammation, and electrospray ionization mass spectrometry [PDF]

open access: yesDevelopmental Medicine & Child Neurology, 2021
This commentary is on the original article by Yan et al. on pages 552–559 of this issue.
openaire   +3 more sources

The Aging Substantia Nigra is Characterized by ROS Accumulation Potentially Resulting in Increased Neuroinflammation and Cytoskeletal Remodeling

open access: yesAdvanced Biology, EarlyView.
Definition of study groups, including young individuals (n = 7 mean age: 28.7 years), middle aged individuals (n = 14 mean age: 62.3 years) and elderly individuals (n = 14 mean age: 83.9 years). Condensed workflow including sample preparation (sample lysis and tryptic digestion), mass spectrometric measurements and subsequent data and statistical ...
Britta Eggers   +10 more
wiley   +1 more source

Current developments in LC-MS for pharmaceutical analysis [PDF]

open access: yes, 2002
The current developments in liquid chromatography-mass spectrometry (LC-MS) and its applications to the analysis of pharmaceuticals are reviewed. Various mass spectrometric techniques, including electrospray and nanospray ionization, atmospheric pressure
Lim, Chang-Kee, Lord, Gwyn A.
core   +1 more source

Removing Homocoupling Defects in Alkoxy/Alkyl‐PBTTT Enhances Polymer:Fullerene Co‐Crystal Formation and Stability

open access: yesAdvanced Functional Materials, EarlyView.
PBTTT‐OR‐R, a C14‐alkoxy/alkyl‐PBTTT polymer derivative, is of substantial interest for optoelectronics due to its specific fullerene intercalation behavior and enhanced charge‐transfer absorption. Comparing this polymer with (S) and without (O) homocoupling defects reveals that PBTTT‐OR‐R(O) forms stable co‐crystals with PC61BM, while PBTTT‐OR‐R(S ...
Zhen Liu   +14 more
wiley   +1 more source

Recent Development on the Detection and Monitoring of Chemical Intermediates by Ambient Mass Spectrometry [PDF]

open access: yesZhipu Xuebao
Along with the development of science and technology, chemical reactions exhibit an important role in various fileds including synthesis, chemical engineering, energy, environment, biology and medicine.
GE Xi-yang1   +3 more
doaj  

Matrix effect in bio-analysis of illicit drugs with LC-MS/MS: Influence of ionization type, sample preparation, and biofluid [PDF]

open access: yes, 2003
The purpose of the present work was to evaluate the synergistic effect of ionization type, sample preparation technique, and bio-fluid on the presence of matrix effect in quantitative liquid chromatography (LC)-MS/MS analysis of illicit drugs by post ...
Dams, Riet   +3 more
core   +1 more source

Switching From Acceptor to FRET Donor: How the Organic Solar Cell Architecture Can Change the Role of a Chromophore

open access: yesAdvanced Functional Materials, EarlyView.
The non‐fullerene acceptor o‐IDT‐BT‐DCV is used in both binary and ternary blends to investigate the role that it plays in each device architecture. The charge generation pathways are found to differ between the binary and ternary blends with o‐IDT‐BT‐DCV becoming a second donor in the ternary blend.
Hui Jin   +10 more
wiley   +1 more source

Proton Dynamics in Protein Mass Spectrometry [PDF]

open access: yes, 2017
Native electrospray ionization/ion mobility-mass spectrometry (ESI/IM-MS) allows an accurate determination of low-resolution structural features of proteins. Yet, the presence of proton dynamics, observed already by us for DNA in the gas phase, and its impact on protein structural determinants, have not been investigated so far.
arxiv   +1 more source

Mass-Resolved Electronic Circular Dichroism Ion Spectroscopy [PDF]

open access: yes, 2020
DNA and proteins are chiral: their three-dimensional structure cannot be superimposed with its mirror image. Circular dichroism spectroscopy is widely used to characterize chiral compounds, but data interpretation is difficult in the case of mixtures. We recorded for the first time the electronic circular dichroism spectra of DNA helices separated in a
arxiv   +1 more source

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