Results 41 to 50 of about 460,066 (283)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Effects of Electrostatic Field and CO₂ Interaction on Growth and Physiological Metabolism in Asparagus

Agriculture
Asparagus (Asparagus officinalis L.) is a highly nutritious vegetable rich in various bioactive compounds. Ensuring both yield improvement and quality preservation is a shared goal for producers and researchers.
Xinyuan Liu, Lirui Liang, Peiran Chen, Wenjun Peng, Kexin Guo, Xiaole Huang, Chi Qin, Zijing Luo, Kewen Ouyang, Chengyao Jiang, Mengyao Li, Tonghua Pan, Yangxia Zheng, Wei Lu   +13 more
doaj   +1 more source

Electrostatic Fluctuations in Soap Films

, 2002
A field theory to describe electrostatic interactions in soap films, described by electric multi-layers with a generalized thermodynamic surface-charging mechanism, is studied.
Dean, D. S., Horgan, R. R.
core   +1 more source

Electromagnetic field generation in the downstream of electrostatic shocks due to electron trapping [PDF]

, 2014
A new magnetic field generation mechanism in electrostatic shocks is found, which can produce fields with magnetic energy density as high as 0.01 of the kinetic energy density of the flows on time scales $ \tilde \, 10^4 \, {\omega}_{pe}^{-1}$.
Fonseca, R. A., Grismayer, T., Silva, L. O., Stockem, A.   +3 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Laboratory measurements of electrostatic solitary structures generated by electron beam injection [PDF]

, 2010
Electrostatic solitary structures are generated by injection of a suprathermal electron beam parallel to the magnetic field in a laboratory plasma. Electric microprobes with tips smaller than the Debye length ($\lambda_{De}$) enabled the measurement of ...
Bertrand Lefebvre, D. G. Swanson, Franklin Chiang, Jack Judy, Jolene Pickett, Li-Jen Chen, Patrick Pribyl, Paul Kintner, Stephen Vincena, Walter Gekelman   +9 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Field distribution in a coaxial electrostatic wiggler

Physical Review Special Topics. Accelerators and Beams, 2010
The field distribution in a coaxial electrostatic wiggler corresponds to the special solution of a Laplace equation in a cylindrical coordinate system with a boundary value problem of sinusoidal ripples.
Shi-Chang Zhang
doaj   +1 more source