Results 61 to 70 of about 460,066 (283)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Calculation of the structure of electrostatic quadrupole-cylindrical fields

open access: yesҚарағанды университетінің хабаршысы. Физика сериясы, 2018
The paper is devoted to the investigation of electrostatic quadrupole-cylindrical fields. Calculation of the structure of electrostatic quadrupole-cylindrical fields, synthesized on the basis of the sum of the base cylindrical field and axially ...
Zh.T. Kambarova, А.О. Saulebekov
doaj  

Simulation study of the filamentation of counter-streaming beams of the electrons and positrons in plasmas

open access: yes, 2009
The filamentation instability driven by two spatially uniform and counter-streaming beams of charged particles in plasmas is modelled by a particle-in-cell (PIC) simulation. Each beam consists of the electrons and positrons.
Dieckmann, M E, Shukla, P K, Stenflo, L
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Molecular Study on Conformational Changes in Trypsin Inhibitors in Multidirectional Electrostatic Fields

open access: yesApplied Sciences
Proteins undergo a series of conformational changes when affected by the applied electric field, which changes their functions and properties. The conformational changes in proteins in various electric fields are different due to their internal ...
Mingyan Hou   +6 more
doaj   +1 more source

GENERALIZATION OF THE THOMSON FORMULA FOR HOMOGENEOUS HARMONIC FUNCTIONS

open access: yesSt. Petersburg Polytechnical University Journal: Physics and Mathematics, 2019
It is shown that the Thomson formula for three-dimensional harmonic homogeneous functions can be generalized if, instead of purely algebraic linear expressions, one uses a linear algebraic form with the participation of the first order partial ...
Berdnikov Alexander   +3 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Simulation Analysis of High Voltage Electrical Box Electric Field for Centralized Power EMUs

open access: yes机车电传动, 2020
According to the principle of main circuit for centralized power EMUs in China, the high voltage electrical box equipped with two main circuit breakers was researched and designed, which not only optimized the arrangement of roof equipments, but also ...
Congjian JIANG, Tao LI, Yingyu YANG
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

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