Results 41 to 50 of about 15,198 (215)

Immunomodulation of COVID‐19 severity by helminth co‐infection: Implications for COVID‐19 vaccine efficacy

Immunity, Inflammation and Disease, Volume 10, Issue 3, March 2022., 2022
Helminth co‐infection could modulate the severity of COVID‐19. Not all parasites will have immunomodulatory properties. Lessons from respiratory viruses coinfected with helminth have been shown reduced vaccine efficacy. Helminth co‐infection and antihelminthic therapy could reduce and enhance the efficacy of COVID‐19 vaccines, respectively.
Yibeltal Akelew, Henok Andualem, Endris Ebrahim, Aytenew Atnaf, Wasihun Hailemichael   +4 more
wiley   +1 more source

Pharmacological characterization of novel heteromeric GluCl subtypes from Caenorhabditis elegans and parasitic nematodes

British Journal of Pharmacology, Volume 179, Issue 6, Page 1264-1279, March 2022., 2022
Background and Purpose Macrocyclic lactones are the most widely used broad‐spectrum anthelmintic drugs for the treatment of parasitic nematodes affecting both human and animal health. Macrocyclic lactones are agonists of the nematode glutamate‐gated chloride channels (GluCls). However, for many important nematode species, the GluCls subunit composition
Nicolas Lamassiaude, Elise Courtot, Angélique Corset, Claude L. Charvet, Cédric Neveu   +4 more
wiley   +1 more source

Prevalence of podoconiosis and its associated factors in Gamo zone, Southern Ethiopia, 2021

Journal of Foot and Ankle Research, Volume 15, Issue 1, 2022., 2022
Abstract Background Podoconiosis is a chronic non‐infectious preventable disease. Though not fatal, it may cause social, economic and physical disability. Ethiopia is projected to bear one‐fourth (25%) of the global burden of podoconiosis. Despite its huge economic impact and chronic morbidity and disability, podoconiosis seems to be neglected ...
Tamiru Getachew, Chuchu Churko
wiley   +1 more source

Microarray Patches: Poking a Hole in the Challenges Faced When Delivering Poorly Soluble Drugs

Advanced Functional Materials, Volume 31, Issue 1, January 4, 2021., 2021
This review explores the delivery of hydrophobic compounds to the skin using microarray patches (MAPs). Initially designed to load low doses of hydrophilic and potent therapeutic agents, MAPs are now increasingly considered a viable strategy for the delivery of therapeutically relevant doses of poorly soluble drugs. This somewhat unexpected application
Alejandro J. Paredes, Peter E. McKenna, Inken K. Ramöller, Yara A. Naser, Fabiana Volpe‐Zanutto, Mingshan Li, M. T. A. Abbate, Li Zhao, Chunyang Zhang, Juhaina M. Abu‐Ershaid, Xianbing Dai, Ryan F. Donnelly   +11 more
wiley   +1 more source

Assessment of Etiology of Elephantiasis and Its Associated Risk Factors in Jeldu District, West Shoa, Ethiopia

Journal of Tropical Medicine, Volume 2021, Issue 1, 2021., 2021
Elephantiasis is the main cause of tropical lymphoedema in Ethiopia. The aim of the current study was to assess the etiology of elephantiasis and its associated risk factors. Cross‐sectional community‐based study was carried out from March to May 2020 in seven purposively selected villages of Jeldu district.
Ararsa Negasa, Mebrate Dufera, Pedro P. Chieffi   +2 more
wiley   +1 more source

Assessing the Filariasis Causing Parasites in Adult Mosquitoes and the Vector Mosquito Larval Breeding in Selected Medical Officer of Health Areas in Gampaha District, Sri Lanka

Journal of Tropical Medicine, Volume 2021, Issue 1, 2021., 2021
The present study was conducted to determine the prevalence of filariasis causing parasites in adult mosquitoes and vector mosquito larval breeding in four Medical Officer of Health (MOH) areas in Gampaha district, Sri Lanka. Adult female mosquitoes at their resting places were collected using a prokopack aspirator operated twice a day from 7.00 am to ...
S. A. S. Pilagolla, L. D. Amarasinghe, Pedro P. Chieffi   +2 more
wiley   +1 more source

Knowledge, attitude, practice and associated factors of health professionals towards podoconiosis in Gamo zone, Ethiopia, 2019

Journal of Foot and Ankle Research, Volume 14, Issue 1, 2021., 2021
Abstract Background Podoconiosis is entirely preventable, non‐communicable disease with high potential of elimination. The prevalence of podoconiosis in Ethiopia was 7.45%. One of the pillars for elimination of podoconiosis is morbidity control and management.
Chuchu Churko, Mekuria Asnakew Asfaw, Abayneh Tunje, Eyayou Girma, Zerihun Zerdo   +4 more
wiley   +1 more source

Neglected tropical diseases, neglected data sources, and neglected issues. [PDF]

PLoS Neglected Tropical Diseases, 2007
BACKGROUND: Lymphatic filariasis (LF) is a so-called neglected tropical disease, currently overshadowed by higher-profile efforts to address malaria, tuberculosis, and HIV/AIDS.
Burton H Singer, Carol D Ryff
doaj   +1 more source

Neglected patients with a neglected disease? A qualitative study of lymphatic filariasis. [PDF]

PLoS Neglected Tropical Diseases, 2007
BACKGROUND: Lymphatic filariasis (LF) is a so-called neglected tropical disease, currently overshadowed by higher-profile efforts to address malaria, tuberculosis, and HIV/AIDS.
Myrtle Perera, Margaret Whitehead, David Molyneux, Mirani Weerasooriya, Godfrey Gunatilleke   +4 more
doaj   +1 more source

The burden of neglected tropical diseases in Ethiopia, and opportunities for integrated control and elimination [PDF]

, 2012
Background: Neglected tropical diseases (NTDs) are a group of chronic parasitic diseases and related conditions that are the most common diseases among the 2·7 billion people globally living on less than US$2 per day.
A Alemu, A Aseffa, A Deressa, A Haileamlak, A Yami, Abraham Aseffa, AD Bryceson, Ahmed Ali, AM Dorkenoo, Asrat Hailu, AZ Zein, B Erko, B Erko, B Liese, B Yakob, BA Boatin, C Bogh, C Hanson, C Prasittisuk, C Sikorski, Central Statistical Agency [Ethiopia], ICF International, D Fekadu, DG Addiss, DH Molyneux, DH Molyneux, DR ten Eyck, E Litt, E Negera, E Negera, E Ruiz-Tiben, E Yimer, EW Price, F Demissie, F Tekola, FMOH, FMOH, FMoH, G Davey, G Davey, G Davey, G Mengistu, G Tefera, Gail Davey, GS Smith, H Birrie, H Kloos, H Kloos, J Alvar, J Alvar, JH Kolaczinski, JH Kolaczinski, JO Gyapong, K Bogel, KA Grépin, Kadu Meribo, Kebede Deribe, L Erosie, L Jemaneh, M Fekadu, M Fekadu, M Herrero, MA Brady, MC Baker, Ministry of Health, MJ Burton, MJ Taylor, N Kebede, NB Kabatereine, P Steinmann, PJ Hotez, PJ Hotez, PJ Hotez, PJ Hotez, PJ Hotez, PM Emerson, R ter Horst, RL Pullan, RW Ashford, S Bashaye, S Brooker, S Brooker, S Cairncross, S Negash, SG Gundersen, T Wondimagegnehu, Teshome Gebre, The Carter Center, W Shiferaw, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, Y Berhane, Z Tadesse, ZA Zein   +103 more
core   +2 more sources