Restraint-induced hypoactivity in an elevated plus-maze [PDF]
Brazilian Journal of Medical and Biological Research, 2000 Rodents submitted to restraint stress show decreased activity in an elevated plus-maze (EPM) 24 h later. The objective of the present study was to determine if a certain amount of time is needed after stress for the development of these changes.
C.M. Padovan, F.S. Guimarães
doaj +6 more sources
Time-of-Day and Age Impact on Memory in Elevated Plus-Maze Test in Rats [PDF]
Frontiers in Behavioral Neuroscience, 2018 The purpose of the present study was to establish the effect of daytime and aging on memory in rats in the Elevated Plus-Maze (EPM) test. Young (2-months) and aged (18-months) male Wistar rats were exposed to the EPM test, at the beginning, mid-time or ...
Nicanor Morales-Delgado +8 more
doaj +4 more sources
Effects of test experience, closed-arm wall color, and illumination level on behavior and plasma corticosterone response in an elevated plus maze in male C57BL/6J mice: a challenge against conventional interpretation of the test [PDF]
Molecular Brain, 2021 The elevated plus maze test is a widely used test for assessing anxiety-like behavior and screening novel therapeutic agents in rodents. Previous studies have shown that a variety of internal factors and procedural variables can influence elevated plus ...
Hirotaka Shoji, Tsuyoshi Miyakawa
doaj +2 more sources
H1 but not H2 histamine antagonist receptors mediate anxiety-related behaviors and emotional memory deficit in mice subjected to elevated plus-maze testing [PDF]
Brazilian Journal of Medical and Biological Research, 2013 This study investigated the role of H1 and H2 receptors in anxiety and the retrieval of emotional memory using a Trial 1/Trial 2 (T1/T2) protocol in an elevated plus-maze (EPM). Tests were performed on 2 consecutive days, designated T1 and T2. Before T1,
K.R. Serafim +3 more
doaj +4 more sources
Comparative analysis between Open Field and Elevated Plus Maze tests as a method for evaluating anxiety-like behavior in mice [PDF]
Heliyon, 2023 Anxiety is being increasingly diagnosed in the elderly population. In this sense, epidemiologic data have linked late-life anxiety disorders to increased cognitive decline, morbidity, and even mortality.
Mariah Mesquita de Figueiredo Cerqueira +6 more
doaj +2 more sources
Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests [PDF]
Brazilian Journal of Medical and Biological Research, 2009 The endocannabinoid system is involved in the control of many physiological functions, including the control of emotional states. In rodents, previous exposure to an open field increases the anxiety-like behavior in the elevated plus-maze.
A. Ribeiro +3 more
doaj +4 more sources
Sex differences in the elevated plus-maze test and large open field test in adult Wistar rats. [PDF]
Pharmacol Biochem Behav, 2021 Knight P +5 more
europepmc +3 more sources
High-Fat Diet Enhances Working Memory in the Y-Maze Test in Male C57BL/6J Mice with Less Anxiety in the Elevated Plus Maze Test. [PDF]
Nutrients, 2020 Yoshizaki K, Asai M, Hara T.
europepmc +3 more sources
Sex-dependent differences in the anxiolytic-like effect of cannabidiol in the elevated plus-maze. [PDF]
J Psychopharmacol, 2022 Fabris D +8 more
europepmc +2 more sources
Exploratory behavior alteration as an epileptic comorbidity in elevated plus maze test [PDF]
Medicinski Podmladak, 2017 Introduction: Epileptic seizure consists of preictal, ictal and postictal period. Postictal period is characterized by a variety of psychiatric phenomenon of which the most frequent ones are anxiety and depressive disorder.
Ademović Anida +6 more
doaj +2 more sources