Results 151 to 160 of about 64,796 (205)
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Anxiogenic stimuli in the elevated plus-maze
Pharmacology Biochemistry and Behavior, 1993Untreated rats normally avoid the open arms of the "elevated plus-maze," preferring instead the closed arms, whereas rats treated with antianxiety drugs (e.g., diazepam) show far less open-arm avoidance. Although it has often been assumed that rats avoid the open arms because of novelty, height, or open space, the anxiogenic role of these stimuli in ...
D, Treit, J, Menard, C, Royan
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Anxiety, defence and the elevated plus-maze
Neuroscience & Biobehavioral Reviews, 1997The elevated plus-maze test has been in use as a rodent model of anxiety for a decade, and is representative of those tests that are based upon the study of spontaneous behaviour patterns and which have high ecological validity. The origins of the test in studies of the relationship between exploration and fear are reviewed, and attention is drawn to ...
R J, Rodgers, A, Dalvi
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Elevated Plus Maze on Based Computer Vision
2007 IEEE 15th Signal Processing and Communications Applications, 2007This paper presents a novel method for rat detection and tracking in a platform known as elevated-plus maze and for recording the rat movements as a time elapsed in specific regions in real time surveillance systems. First, the location of plus maze platform is automatically determined by using hough transform.
Mustafa Sahin +3 more
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Antianxiety effect of cannabidiol in the elevated plus-maze
Psychopharmacology, 1990In order to assess the presence of anxiolytic properties in cannabidiol (CBD) the drug was tested in an elevated plus-maze model of anxiety, in rats. Doses of 2.5, 5.0 and 10.0 mg/kg significantly increased the entry ratio (open/total number of entries), an anxiolytic-like effect. CBD at a dose of 20.0 mg/kg was no longer effective.
F S, Guimarães +3 more
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Anxiolytic effect of cannabidiol derivatives in the elevated plus-maze
General Pharmacology: The Vascular System, 19941. In order to assess the presence of anxiolytic properties in cannabidiol (CBD) derivatives HU-219, HU-252 and HU-261, these drugs were tested in rats submitted to the elevated plus-maze model of anxiety. 2. Additional groups received diazepam or CBD.
F S, Guimarães +3 more
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Behavior ontogeny in the elevated plus‐maze: prenatal stress effects
International Journal of Developmental Neuroscience, 2006AbstractPrenatal stress is a putative model for studying some psychopathological disorders. Indeed, submitting pregnant animals to stress leads to enhanced anxiety in the adult offspring. However, little is known about how prenatal stress effects interacts with anxiety throughout development. To study this issue, prenatally stressed rats were tested in
Celio, Estanislau, Silvio, Morato
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Ethopharmacological analysis of rat behavior on the elevated plus-maze
Pharmacology Biochemistry and Behavior, 1994Behavioral categories were measured in rats left on an elevated plus-maze for 5 min, in addition to the traditional measures. Four independent factors emerged from a factor analysis. The variables that loaded highly and positively on Factor 1, seemingly related with anxiety, were: number of entries onto open arms, time spent on open arms, percentage of
Cruz, APM, Frei, F., Graeff, F. G.
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Ethopharmacological analysis of the open elevated plus-maze in mice
Behavioural Brain Research, 2013Exposure of rodents to an open elevated plus-maze (oEPM) elicits antinociception and increases plasma corticosterone levels. However, no studies have yet assessed the defensive behaviour repertoire of animals in this modified test. In Experiment 1, factor analysis was employed to characterise the behavioural profile of mice exposed to the oEPM ...
Sorregotti, Tatiani +4 more
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