Results 31 to 40 of about 65,567 (242)

Chronic consumption of distilled sugarcane spirit induces anxiolytic-like effects in mice

open access: yesClinics, 2011
OBJECTIVE: Chronic ethanol consumption is a major public health problem throughout the world. We investigated the anxiolytic-like effects and the possible ever injury induced by the chronic consumption of ethanol or sugarcane spirit in mice.
Maria Clecia P. Sena   +5 more
doaj   +1 more source

Lifelong behavioral and neuropathological consequences of repetitive mild traumatic brain injury [PDF]

open access: yes, 2017
Objective: Exposure to repetitive concussion, or mild traumatic brain injury (mTBI), has been linked with increased risk of long-term neurodegenerative changes, specifically chronic traumatic encephalopathy (CTE).
Acker, Christopher M.   +11 more
core   +2 more sources

Administration of the antioxidant n-acetyl-cysteine in pregnant mice has long-term positive effects on metabolic and behavioral endpoints of male and female offspring prenatally exposed to a high-fat diet [PDF]

open access: yes, 2018
A growing body of evidence suggests the consumption of high-fat diet (HFD) during pregnancy to model maternal obesity and the associated increase in oxidative stress (OS), might act as powerful prenatal stressors, leading to adult stress-related ...
Arese, Marzia   +6 more
core   +3 more sources

Overexpression of the type 1 adenylyl cyclase in the forebrain leads to deficits of behavioral inhibition [PDF]

open access: yes, 2015
The type 1 adenylyl cyclase (AC1) is an activity-dependent, calcium-stimulated adenylyl cyclase expressed in the nervous system that is implicated in memory formation. We examined the locomotor activity, and impulsive and social behaviors of AC1+ mice, a
Cao, Hong   +4 more
core   +2 more sources

Mechanism of the Interaction of Cannabinoid System in Central Amygdale with Opioid System [PDF]

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2008
Background and objectives Cannabinoids which are active compounds of marijuana show some pharmacological effects similar to the opioids. There are also functional interactions between both cannabinoid and opioid systems. In this study we investigated the
SH Sarahroodi   +3 more
doaj   +1 more source

Mutant Tau knock-in mice display frontotemporal dementia relevant behaviour and histopathology [PDF]

open access: yes, 2016
Peer ...
Drever, Benjamin D.   +7 more
core   +3 more sources

Early Cognitive/Social Deficits and Late Motor Phenotype in Conditional Wild-Type TDP-43 Transgenic Mice [PDF]

open access: yes, 2016
Frontotemporal Dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two neurodegenerative diseases associated to mislocalization and aggregation of TAR DNA-binding protein 43 (TDP-43).
Alfieri, Julio Armando   +2 more
core   +2 more sources

The Gerbil Elevated Plus-Maze I Behavioral Characterization and Pharmacological Validation [PDF]

open access: yesNeuropsychopharmacology, 2002
Several neurokinin NK1 receptor antagonists currently being developed for anxiety and depression have reduced affinity for the rat and mouse NK1 receptor compared with human. Consequently, it has proven difficult to test these agents in traditional rat and mouse models of anxiety and depression.
Geoffrey B, Varty   +4 more
openaire   +2 more sources

Identifying reliable traits across laboratory mouse exploration arenas: A meta-analysis [PDF]

open access: yes, 2012
This study is a meta-analysis of 367 mice from a collection of behaviour neuroscience and behaviour genetic studies run in the same lab in Zurich, Switzerland.
Hans-Peter Lipp   +2 more
core   +2 more sources

Anti-anxiety Activity of Methanolic Extracts of Different Parts of Angelica archangelica Linn.

open access: yesJournal of Traditional and Complementary Medicine, 2012
Angelica archangelica Linn.is a herb distributed in tropical and subtropical regions of the world. In Indian and Chinese system of medicine, it is used for nervous disorders and cerebral diseases. Previously the aqueous extract of the A. archangelica was
Dinesh Kumar, Zulfiqar Ali Bhat
doaj   +1 more source

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