Elevated plus maze test for mice v1
The elevated plus maze is a classical test to screen anxiety-like behaviors in laboratory animals. This protocol is optimized to mice. The protocol also describes the use of Biobserve Viewer, which is is a software to track online the movement of animals.
Csilla Novák +2 more
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Reactivity to conditioned threat cues is distinct from exploratory drive in the elevated plus maze. [PDF]
Eur J Neurosci, 2023 Hilton JR +9 more
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Prior test experience produces changes of t-patterns spatial distribution in the elevated plus maze test [PDF]
, 2014 Aim of present research was to investigate in male Wistar rats whether a prior elevated plus maze experience modifies the temporal structure of the behavioral response following a retest applied after 24h.
Arabo, A +7 more
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Sex-dependent differences in the anxiolytic-like effect of cannabidiol in the elevated plus-maze. [PDF]
J Psychopharmacol, 2022 Fabris D +8 more
europepmc +1 more source
Study of sedative, preanaesthetic and anxiolytic effects of herbal extract of Lavandula stoechas in comparison with diazepam in rat [PDF]
Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2010 Lavandula stoechas grows naturally in most parts of the world specifically south France, the Mediterranean region and Torento. The plant has various pharmacological properties including analgesic, anti-inflammatory, antidepressant, hypnotic, sedative and
A Rezaie, B Jafari, M Jalilzadeh
doaj
Drug Target Insights, 2015 Nitric oxide (NO) is an atypical neurotransmitter that causes changes in cognition. Nitric oxide synthase (NOS) and guanylate cyclase (GC) inhibitors have been shown to exert some effects on cognition in previous studies; however, the findings have been controversial.
Oguz Mutlu +6 more
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Effect of apparatus characteristics on anxiety-like behavior in young adult and old mice of both sexes assessed by the elevated plus maze assay. [PDF]
Front Behav Neurosci, 2023 Gaspar L +3 more
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Evaluation of anxiolytic potential of Linum usitatissimum oil in wistar rats
Journal of Applied Pharmaceutical Research, 2014 The objective of the present study was to evaluate the anxiolytic potential of the Linum usitatissimum (Flax seed) oil (5ml and 2.5ml/kg) in wistar rats by using Elevated plus maze (EPM) model and 5ml and 10 ml/kg in Lithium induced head twitches model ...
Trilochan Satapathy +3 more
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Exploratory behavior alteration as an epileptic comorbidity in elevated plus maze test [PDF]
Medicinski Podmladak, 2017 Introduction: Epileptic seizure consists of preictal, ictal and postictal period. Postictal period is characterized by a variety of psychiatric phenomenon of which the most frequent ones are anxiety and depressive disorder.
Ademović Anida +6 more
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Memory-impairing effects of local anesthetics in an elevated plus-maze test in mice
Brazilian Journal of Medical and Biological Research, 1998 Post-training intracerebroventricular administration of procaine (20 µg/µl) and dimethocaine (10 or 20 µg/µl), local anesthetics of the ester class, prolonged the latency (s) in the retention test of male and female 3-month-old Swiss albino mice (25-35 g
S.L. Blatt, R.N. Takahashi
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