Results 81 to 90 of about 96,671 (319)
Evaluation of behavior in transgenic mouse models to understand human congenital pain conditions [PDF]
, 2018 BACKGROUND: Containing a brain for signal processing and decision making, and a peripheral component for sensation and response, the nervous system provides higher organisms a powerful method of interacting with their environment.
Bullock, Daniel
core
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden [PDF]
, 2010 Background It has traditionally been thought that the pathological accumulation of tau in Alzheimer's disease and other tauopathies facilitates neurodegeneration, which in turn leads to cognitive impairment.
A de Calignon +38 more
core +6 more sources
Behavioral and Brain Functions, 2014 BackgroundCholesterol is an essential component of brain and nerve cells and is essential for maintaining the function of the nervous system. Epidemiological studies showed that patients suffering from anxiety disorders have higher serum cholesterol ...
Xu Hu +7 more
semanticscholar +1 more source
Bulletin of Faculty of Pharmacy Cairo University, 2014 Stress alters psychological diseases such as anxiety and depression. Protein malnutrition (PM) contributes to psychological disorders. The present study aimed to investigate the effect of biphenyl dimethyl dicarboxylate (DDB) on anxiety of ...
M.F. Sabry, M.R. Hamed, M.E. El sayed
doaj +1 more source
Advanced Science, EarlyView.Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
Diet transition to a high-fat diet for 3 weeks reduces brain omega-3-fatty acid levels, alters BDNF signaling and induces anxiety & depression-like behavior in adult rats [PDF]
, 2012 Background: The consumption of diets high in calories and low in nutrient value is becoming increasingly common in modern society, which can lead to metabolic disorders like diabetes and obesity, and potentially to psychiatric disorders.
Fernando Gomez-Pinilla +2 more
core +1 more source
Sex-Specific Effects of a Wartime-Like Radiation Exposure on Cognitive Function. [PDF]
, 2020 Evaluating the risk for central nervous system (CNS) effects after whole-body or partial-body irradiation presents challenges due in part to the varied exposure scenarios in the context of occupational, accidental or wartime releases.
Acharya, Munjal M +7 more
core
Primary Blast Traumatic Brain Injury in the Rat: Relating Diffusion Tensor Imaging and Behavior [PDF]
, 2013 The incidence of traumatic brain injury (TBI) among military personnel is at its highest point in U.S. history. Experimental animal models of blast have provided a wealth of insight into blast injury.
Budde, Matthew D. +5 more
core +2 more sources
Anxiolytic-like effects of mitragynine in the open-field and elevated plus-maze tests in rats
Journal of Physiological Sciences, 2014 The effects of mitragynine on anxiety-related behaviours in the open-field and elevated plus-maze tests were evaluated. Male Sprague–Dawley rats were orally treated with mitragynine (10, 20 and 40 mg/kg) or diazepam (10 mg/kg) 60 min before behavioural ...
A. I. Hazim +4 more
semanticscholar +1 more source
Elevated plus-maze behavior in adult offspring of selectively bred rats
Physiology & Behavior, 1996 Animals sampled from the third generation (S3) of selective breeding of N:NIH strain rats based on ultrasonic vocalization (USV) rates in infancy (High, Low, and Random lines) were tested as adults on the elevated plus maze, a well-validated test of anxiety.
G S, Dichter, S A, Brunelli, M A, Hofer
openaire +2 more sources