Results 71 to 80 of about 273,405 (289)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Spatial dynamics of built-up land development prediction based on cellular automata markov chain in tsunami prone areas of Ternate Island, Indonesia [PDF]

BIO Web of Conferences
Ternate Island's coastal geography makes it highly susceptible to tsunamis, and increasing built-up land intensifies this risk. This study analyzes the spatial dynamics of built-up land development in tsunami-prone areas using land cover data from 2005 ...
Rifai Ahmad, Rakuasa Heinrich, Khromykh Vadim V., Latue Philia Christi, Rabiyanti Intan, Supriatna   +5 more
doaj   +1 more source

Farming Differentiation in the Rural-urban Interface of the Middle Mountains, Nepal: Application of Analytic Hierarchy Process (AHP)Modeling [PDF]

, 2010
This article investigates the dominant factors of farming differentiation in the rural-urban interface of the densely populated Kathmandu Valley, using the Analytic Hierarchy Process (AHP) modeling. The rural-urban interface in the Kathmandu Valley is
Bhatta, G.D., Doppler, W.
core  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Correlate Mapping of Impervious Surfaces as Flood Risk Assessment Strategy in Owerri, Southeastern Nigeria [PDF]

, 2017
Owerri is rapidly growing in population and built environment, with corresponding, high increase in pavements or paved surfaces. This study explores the integrated approach of Remote Sensing (RS) and Geographic Information systems (GIS) techniques in ...
Anayo D. Udeh, Ikenna E. Osumgborogwu, John D. Njoku, Kingsley O. E. Ukaegbu, Mercy Telu   +4 more
core   +3 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Responses of Soybean to Oxygen Deficiency and Elevated Root-zone Carbon Dioxide Concentration [PDF]

Annals of Botany, 2003
Root flooding is damaging to the growth of crop plants such as soybean (Glycine max L.). Field flooding for 3 d often results in leaf chlorosis, defoliation, cessation of growth and plant death. These effects have been widely attributed solely to a lack of oxygen in the root-zone.
G, Boru, T, Vantoai, J, Alves, D, Hua, M, Knee   +4 more
openaire   +2 more sources

Characterizing the spatial determinants and prevention of malaria in Kenya [PDF]

, 2019
The United Nations' Sustainable Development Goal 3 is to ensure health and well-being for all at all ages with a specific target to end malaria by 2030.
Gopal, Sucharita, Ma, Yaxiong, Pitts, Joshua, Were, Lawrence, Xin, Chen   +4 more
core   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

A propagating ERKII switch forms zones of elevated dendritic activation correlated with plasticity [PDF]

HFSP Journal, 2007
Strong inputs to neurons trigger complex biochemical events leading to synaptic plasticity. These biochemical events occur at many spatial scales, ranging from submicron dendritic spines to signals that propagate hundreds of microns from dendrites to the nucleus.
Sriram M, Ajay, Upinder S, Bhalla
openaire   +2 more sources