Results 51 to 60 of about 709,504 (268)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Costing analysis of a Queensland community corrections hepatitis C screening program
BMC Health Services ResearchBackground People involved with the criminal justice system typically have lower healthcare engagement and higher risk of hepatitis C virus (HCV) infection than the general population. Interventions run at community corrections centres have the potential
Kelly Maynard +6 more
doaj +1 more source
THE ELIMINATION OF THE MIDWIFE [PDF]
JAMA: The Journal of the American Medical Association, 1913 It is most gratifying to note the interest which has been awakened in the midwife problem during the past few years. The outlook is hopeful and an attempted early solution of the question may be anticipated. The danger lies in too great haste. Either we are going to settle the matter to our credit and future welfare, or we are going to make a serious ...
openaire +2 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Public Health ChallengesIntroduction Long COVID is a significant public health concern. This study aimed to identify the prevalence, impact, and factors associated with long COVID among young people in Victoria, Australia.
Robin Engelberts +7 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Health equity for young Black sexually minoritized men through their eyes: a qualitative study
BMC Public HealthBackground Young Black sexually minoritized men (YBSMM) are a key population for Ending the HIV Epidemic though their care engagement is limited due to inequities shaped by social determinants of health.
Jordan Victorian +6 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source