Results 61 to 70 of about 709,504 (268)

RAT Elimination

EPiC Series in Computing, 2020
Inprocessing techniques have become one of the most promising advancements in SAT solving over the last decade. Some inprocessing techniques modify a propositional formula in non model-perserving ways. These operations are very problematic when Craig inter- polants must be extracted: existing methods take resolution proofs as an input, but these ...
Adrián Rebola-Pardo, Georg Weissenbacher   +1 more
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Insecticide-treated nets mass distribution campaign: benefits and lessons in Zambia

Malaria Journal, 2018
Background Zambia was an early adopter of insecticide-treated nets strategy in 2001, and policy for mass distribution with long-lasting insecticidal nets (LLINs) in 2005. Since then, the country has implemented mass distribution supplemented with routine
Freddie Masaninga, Nawa Mukumbuta, Ketty Ndhlovu, Busiku Hamainza, Pauline Wamulume, Emmanuel Chanda, John Banda, Mercy Mwanza-Ingwe, John M. Miller, Birkinesh Ameneshewa, Abraham Mnzava, Elizabeth Kawesha-Chizema   +11 more
doaj   +1 more source

The use of spatial and genetic tools to assess Plasmodium falciparum transmission in Lusaka, Zambia between 2011 and 2015

Malaria Journal, 2020
Background Zambia has set itself the ambitious target of eliminating malaria by 2021. To continue tracking transmission to zero, new interventions, tools and approaches are required.
Daniel J. Bridges, Sandra Chishimba, Mulenga Mwenda, Anna M. Winters, Erik Slawsky, Brenda Mambwe, Conceptor Mulube, Kelly M. Searle, Aves Hakalima, Roy Mwenechanya, David A. Larsen   +10 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Genotype Complexity Modulates Antimalarial Susceptibility in vitro

Infection and Drug Resistance
Chinedu Ogbonnia Egwu,1,2,* Olusola Ajibaye,1,3,* Fatoumata Bojang,1 Haddijatou Mbye,1 Vincent Ntui Ntui-Njock,1 Ndey Fatou Drammeh,1 Eniyou Cheryll Oriero,1 Alfred Amambua-Ngwa1,* 1Disease Control and Elimination, Medical ...
Egwu CO, Ajibaye O, Bojang F, Mbye H, Ntui-Njock VN, Drammeh NF, Oriero EC, Amambua-Ngwa A   +7 more
doaj  

A framework for identifying cost efficiencies in malaria routine data quality audits: methodology and application in Zambia

Malaria Journal
Background Routine data quality audits (RDQA) are a critical activity conducted by many country malaria programs to assess the reliability of reported malaria data, but it requires significant human and financial resources.
An Nguyen, Prudence Malama, Christopher Lungu, Mercy Mwanza, Dingase Phiri, Kafula Silumbe, Japhet Chiwaula, Michael Hainsworth, Smita Das, Arantxa Roca-Feltrer   +9 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Patients’ experience of accessing hepatitis C treatment through the Myanmar national hepatitis C treatment program: a qualitative evaluation

BMC Health Services Research
Background Globally, 56.8 million people are living with hepatitis C and over three-quarters of those reside in low and middle-income countries (LMICs). Barriers and enablers to hepatitis C care among people who inject drugs in high-income countries are ...
Bridget Draper, Win Lei Yee, Anna Bowring, Win Naing, Khin Pyone Kyi, Hla Htay, Jessica Howell, Margaret Hellard, Alisa Pedrana   +8 more
doaj   +1 more source

Eliminating Ditransitives [PDF]

, 2012
We discuss how higher arity verbs such as give or promise can be treated in an algebraic framework that admits only unary and binary relations and does not rely on event variables.
openaire   +1 more source