Results 21 to 30 of about 17,019 (196)

Role of Hydroxyapatite and Ellagic Acid in the Osteogenesis [PDF]

European Journal of Dentistry, 2020
Abstract Objective Ellagic acid (EA), a phenolic antioxidant, has benefits in bone health and wound healing. The combination of EA and hydroxyapatite (HA) (EA-HA) is expected to increase osteogenesis. The aim of this study was to analyze osteogenesis after application of EA-HA according to the number of osteoblasts and osteoclasts in the bone and the ...
Agung Satria Wardhana, Intan Nirwana, Hendrik Setia Budi, Meircurius Dwi Condro Surboyo   +3 more
openaire   +2 more sources

Pharmacokinetics study of a supersaturatable self-microemulsifying drug delivery system for ellagic acid by UHPLC-Q-TOF-MS

Acta Pharmaceutica, 2021
To evaluate the bioavailability of ellagic acid loaded super-saturatable self-microemulsifying drug delivery system (S-SMEDDS), its pharmacokinetic properties were studied in rats with an ultra-high performance liquid chromatography-quadrupole time-of ...
Wang Jinglong, Fan Liqun, Zhang Lihua, Zheng Dandan, Wang Yingzi, Sun Xiao, Ji Yonghui   +6 more
doaj   +1 more source

Ellagic Acid Increases Stress Resistance via Insulin/IGF-1 Signaling Pathway in Caenorhabditis elegans

Molecules, 2022
Ellagic acid is a natural polyphenol found in various fruits and vegetables. Numerous studies have shown that ellagic acid has beneficial effects on human health.
Shuju Bai, Yaoru Yu, Lu An, Wenbo Wang, Xueqi Fu, Jing Chen, Junfeng Ma   +6 more
doaj   +1 more source

Ellagic acid and its fermentative derivative urolithin A show reverse effects on the gp91-phox gene expression, resulting in opposite alterations in all-trans retinoic acid-induced superoxide generating activity of U937 cells

Biochemistry and Biophysics Reports, 2021
Ellagitannins (esters composed of glucose and ellagic acid) are hydrolyzed to generate ellagic acid in gut followed by conversion of ellagic acid to urolithins such as urolithin A by intestinal bacteria.
Hidehiko Kikuchi, Kaori Harata, Harishkumar Madhyastha, Futoshi Kuribayashi   +3 more
doaj   +1 more source

Synthesis of ellagic acid glucoside using glucansucrase from Leuconostoc and characterization of this glucoside as a functional neuroprotective agent

AMB Express, 2021
Ellagic acid glucoside was synthesized via transglucosylation using sucrose and glucansucrase derived from Leuconostoc mesenteroides B-512 FMCM. After such enzymatic synthesis, the product was purified by 50% ethyl acetate fraction and C18 column ...
Hyejin Yu, Hana Jeong, Kwang-Yeol Yang, Jeong-Yong Cho, In Ki Hong, Seung-Hee Nam   +5 more
doaj   +1 more source

Protective Effects of Ellagic Acid Against Alcoholic Liver Disease in Mice

Frontiers in Nutrition, 2021
Ellagic acid, a natural polyphenolic compound commonly present in vegetables, fruits, nuts, and other edible plants, exerts many pharmacological activities.
Liang Zhao, Arshad Mehmood, Mohamed Mohamed Soliman, Asra Iftikhar, Maryam Iftikhar, Salama Mostafa Aboelenin, Chengtao Wang   +6 more
doaj   +1 more source

The Effect of Ellagic Acid on Coagulation in Vivo [PDF]

Blood, 1966
Abstract Ellagic acid shortens the silicone and glass clotting times of the blood of dogs, cats, rabbits and rats. The silicone clotting time is reduced so as to make it almost equal to the normal glass clotting time for 5 to 30 minutes after the injection of the agent.
A, Girolami, D, Agostino, E E, Cliffton
openaire   +2 more sources

Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway

Frontiers in Pharmacology, 2021
Idiopathic pulmonary fibrosis is a progressive lung disease with high mortality and limited therapy that is characterized by epithelial cell damage and fibroblast activation.
Xiaohe Li, Xiaohe Li, Kai Huang, Xiaowei Liu, Xiaowei Liu, Hao Ruan, Hao Ruan, Ling Ma, Ling Ma, Jingjing Liang, Jingjing Liang, Yunyao Cui, Yunyao Cui, Yanhua Wang, Shuyang Wu, Hailong Li, Yuli Wei, Zeping Li, Zeping Li, Jingjing Gao, Bo Yang, Xiaoping Li, Guang Yang, Honggang Zhou, Honggang Zhou, Cheng Yang, Cheng Yang   +26 more
doaj   +1 more source

Nano Ellagic Acid Counteracts Cisplatin-Induced Upregulation in OAT1 and OAT3: A Possible Nephroprotection Mechanism

Molecules, 2020
Cisplatin is an anticancer drug commonly used for solid tumors. However, it causes nephrotoxicity. OAT1 and OAT3 are organic anion transporters known to contribute to the uptake of cisplatin into renal tubular cells.
Thikryat Neamatallah, Nagla El-Shitany, Aymn Abbas, Basma G. Eid, Steve Harakeh, Soad Ali, Shaker Mousa   +6 more
doaj   +1 more source

Preparation of β-CD-Ellagic Acid Microspheres and Their Effects on HepG2 Cell Proliferation

Molecules, 2017
Objective: In this study, β-cyclodextrin (β-CD) was chosen as the coating for ellagic acid to prepare ellagic acid microspheres, and the effect of microspheres on the growth of HepG2 cells was observed.
Hongkai Wang, Yingxia Zhang, Zhongjing Tian, Jing Ma, Meiling Kang, Chengshi Ding, Dongfeng Ming   +6 more
doaj   +1 more source