Results 91 to 100 of about 17,066 (199)

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

Journal of Clinical Laboratory Analysis, Volume 40, Issue 15, August 2026.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka, Risa Kaneshige, Seika Nakamura, Yukari Motoki, Junzo Nojima   +4 more
wiley   +1 more source

Protective Effects of Lycopene and Ellagic Acid on Gonadal Tissue, Maternal Newborn Rats Induced by Cadmiumchloride

Armaghane Danesh Bimonthly Journal, 2015
Background & aim: Cadmium is a toxin which reduces the ability of the reproduction in humans .Different antioxidants damaging effects of toxins are eliminated .The purpose of this study was to investigate the protective effects of lycopene and Ellagic ...
K Hoshmand Motlagh, M Jafari Barmak, A Dehghan Manshadi, A Vahdati, HR Zargar, R Mahmoudi   +5 more
doaj  

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

The Effects of Proresolution of Ellagic Acid in an Experimental Model of Allergic Airway Inflammation

Mediators of Inflammation, 2013
Asthma is a disease of airway inflammation characterized by airway hyperresponsiveness, eosinophilic inflammation, and hypersecretion of mucus. Ellagic acid, a compound derived from medicinal plants and fruits, has shown anti-inflammatory activity in ...
Claudiney de Freitas Alves, Giovanna Natalia Angeli, Daniely Cornélio Favarin, Edinéia Lemos de Andrade, Javier Emilio Lazo Chica, Lúcia Helena Faccioli, Paulo Roberto da Silva, Alexandre de Paula Rogerio   +7 more
doaj   +1 more source

Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei, Xiyue Xiong, Lu Zhang, Jian Zhang, Lawrence W. C. Chan, Hong Jiang, Qingqing Xiong, Changtao Hu, Jie Chen, Sijun Yang   +9 more
wiley   +1 more source

Metabolite‐Driven Biological Activity of Mandragora autumnalis and Spartium junceum: A Comparative LC‐MS/MS Study on Antioxidant, Cholinesterase, and Carbonic Anhydrase Inhibition

ChemistryOpen, Volume 15, Issue 8, August 2026.
Low‐molecular‐weight phenolic acids in M. autumnalis were associated with antioxidant activity, AChE, and hCA inhibition effects, whereas flavonoid‐rich S. junceum displayed BChE‐oriented inhibition effect and antibacterial activity. LC‐MS/MS‐based metabolite profiling linked distinct chemical compositions to bioactivity patterns, supporting further ...
Kubra Aslan, Esra Elbir, Yusuf Bicakci, Silanur Ozdogan, Mustafa Abdullah Yilmaz, Ilhami Gulcin   +5 more
wiley   +1 more source

How does leaf age affect performance? A comparative study of essential oils from young and mature Eucalyptus globulus leaves in crop protection

Pest Management Science, Volume 82, Issue 8, Page 7510-7525, August 2026.
Leaf age influences metabolomic profiling but not bioactivity of Eucalyptus globulus essential oils. Leaf age affects volatile levels of young and adult E. globulus oils, but not their bioactivity. Young leaf essential oil had higher contents of α‐ and β‐pinene. AEEO had higher levels of 1,8‐cineole and trans‐pinocarveol.
Mafalda Pinto, Cristiano Soares, Ana Cristina Figueiredo, Joana Neto, Pedro A S Sousa, Ana A R M Aguiar, Michele Narduzzi, Chiara Antonelli, Anna Maria Vettraino, Tatiana Andreani, Fernando Tavares, Fernanda Fidalgo   +11 more
wiley   +1 more source

The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis

Phytotherapy Research, Volume 40, Issue 8, Page 5071-5089, August 2026.
ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang, YongJun Du, Yanmei Hou, Liangliang Hao, Zhen Chen, Haoyang Xie, Chuantao Zhang, Lei Li   +7 more
wiley   +1 more source

Carotenoids From Amazonian Fruits as Functional Pigments in Active and Intelligent Food Packaging: Materials, Stability, and Technological Performance

Journal of Food Science, Volume 91, Issue 8, August 2026.
ABSTRACT Amazonian fruits represent an underexplored source of carotenoids with high technological, functional, and economic potential for applications in food packaging. In recent years, active and intelligent packaging systems based on biopolymers and natural pigments have emerged as effective strategies for extending shelf life, monitoring food ...
Rafaela Julyana Barboza Devos, Luana Regina Pereira Alves, Rômulo Alves Morais, Hermanny Matos Silva Sousa, Camila da Costa Gomes, Paulo Eduardo Peres de Sa Peixoto Junior, Glêndara Aparecida de Souza Martins   +6 more
wiley   +1 more source

Pomegranate Peel Polyphenol Extract Ameliorates Hyperuricemia by Inhibiting Uric Acid Synthesis and Reabsorption

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
The graphical abstract illustrates the action mechanisms through which PPE alleviates HUA by inhibiting XOD activity, and by suppressing the PI3K‐AKT signaling pathway to downregulate the expression of the urate reabsorption transporters URAT1 and GLUT9, thereby promoting renal UA excretion and attenuating renal injury.
Zeyu Yin, Shufei Liang, Gangao Yang, Pingping Guo, Chao Wang, Qingqing Han, Xinhua Song   +6 more
wiley   +1 more source