Results 41 to 50 of about 912,001 (286)

Impairing the production of ribosomal RNA activates mammalian target of rapamycin complex 1 signalling and downstream translation factors [PDF]

, 2014
Ribosome biogenesis is a key process for maintaining protein synthetic capacity in dividing or growing cells, and requires coordinated production of ribosomal proteins and ribosomal RNA (rRNA), including the processing of the latter.
Arora, Baird, Beugnet, Boultwood, Brandenburger, Brenneisen, Browne, Chresta, Christopher G. Proud, Dong, Drygin, Dunlop, Feldman, Fonseca, Fonseca, Fumagalli, Gingras, Grimm, Hannan, Hara, Holzel, Horn, Horos, Huang, Iadevaia, Iadevaia, Jastrzebski, Jefferies, Julien Averous, Killian, Kimball, Kispal, Lam, Le-Bacquer, Lempiainen, Lempiainen, Loreni, Mayer, Mayer, Meyuhas, Miluzio, Montanaro, Oshiro, Patursky-Polischuk, Pearce, Pearson, Peter M. Taylor, Pianese, Popowski, Proud, Redpath, Rodnina, Rohrmoser, Rui Liu, Sancak, Sancak, Sanchez, Sarbassov, Smith, Strezoska, Strezoska, Thoreen, Valentina Iadevaia, Wang, Wang, Willett, Xiao, Yip, Ze Zhang   +68 more
core   +6 more sources

The Elongation of Ovococci [PDF]

Microbial Drug Resistance, 2014
The morphogenesis of ovococci has been reviewed extensively. Recent results have provided new insights concerning the mechanisms of elongation in ovoid bacteria. We present here the proteins involved in the elongation (firmly established and more or less hypothetical) and discuss the relationship between elongation and division of ovococci.
Philippe, Jules, Vernet, Thierry, Zapun, André   +2 more
openaire   +4 more sources

Formation and Evolution of Single Molecule Junctions [PDF]

, 2009
We analyze the formation and evolution statistics of single molecule junctions bonded to gold electrodes using amine, methyl sulfide and dimethyl phosphine link groups by measuring conductance as a function of junction elongation.
Hybertsen, M. S., Kamenetska, M., Koentopp, M., Nuckolls, C., Park, Y. S., Steigerwald, M. L., Venkataraman, L., Whalley, A. C.   +7 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

RNA polymerase interactions and elongation rate

, 2018
We show that non-steric molecular interactions between RNA polymerase (RNAP) motors that move simultaneously on the same DNA track determine strongly the kinetics of transcription elongation.
Belitsky, V., Schütz, G. M.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Machine Learning Model Coupled with Graphical User Interface for Predicting Mechanical Properties of Flax Fiber

Journal of Natural Fibers
Machine learning model coupled with graphical user interface was developed to predict mechanical properties of flax fiber. The experiment was conducted using test setup which applies constant rate of loading (CRL).
T. Nageshkumar, Prateek Shrivastava, L. Ammayapan, Manisha Jagadale, L. K. Nayak, D. B. Shakyawar, Indran Suyambulingam, P. Senthamaraikannan, R. Kumar   +8 more
doaj   +1 more source

Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex [PDF]

, 2018
ELL family transcription factors activate the overall rate of RNA polymerase II (Pol II) transcription elongation by binding directly to Pol II and suppressing its tendency to pause.
Alonso-Nunez, Bahler, Bahler, Banks, Buchan, Cairns, Charles AS Banks, Chou, Christopher W Seidel, Coudreuse, Dana M Gibbon, Elmendorf, Florens, Garg, He, He, Joan W Conaway, Kim, Kimura, Kimura, Kitts, Kong, Langmead, Laurence A Florens, Li, Lin, Luo, Luo, Michael P Washburn, Miller, Monahan, Nimisha Sharma, Oliva, Preeti Dabas, Quinlan, Robinson, Ronald C Conaway, Rustici, Shilatifard, Shilatifard, Simone, Simone, Sneha Gopalan, Sobhian, Suarez, Szklarczyk, Tabb, Takahashi, Thorvaldsdottir, Tsai, Ward, Washburn, Ying Zhang, Yokoyama, Zhang   +54 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The Role of Retained Austenite and Its Carbon Concentration on Elongation of Low Temperature Bainitic Steels at Different Austenitising Temperature

Metals, 2018
The influence of austenitising temperature on the tensile properties of low temperature bainitic steel was investigated. With the increasing austenitising temperature, a significant change of elongation was found between 850 and 950 °C, which was ...
Baoqi Dong, Tingping Hou, Wen Zhou, Guohong Zhang, Kaiming Wu   +4 more
doaj   +1 more source