Results 71 to 80 of about 432,376 (299)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Genetic and Molecular Regulation of Cotton Fiber Initiation and Elongation

open access: yesAgronomy
Cotton fiber, a crucial and sustainable resource for global textile production, undergoes a complex five-stage developmental process, encompassing initiation, elongation, transition, secondary cell wall biosynthesis, and maturation.
Fang Bai, Jodi Scheffler
doaj   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas   +18 more
wiley   +1 more source

THE EFFECT OF LENGTH TIME IN USING POLYAMIDE NETS (PA) MULTIFILAMENT SIZE 210D/15 MESH SIZE ¾ INCH ON THE PART OF THE PURSE SEINE NETS TO THE VALUE OF BREAKING STRENGTH AND ELONGATION

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2021
Fishing gear consists of natural materials (natural fibres) and synthetic materials (synthetic fibres). The advantage of using synthetic materials is more durable. Polyamide is one of the examples of synthetic materials or also known as nylon.
Azzahra T.C., Boesono S.H., Jayanto B.B.
doaj   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen   +18 more
wiley   +1 more source

The impact of annealing temperatures and chemical assays on the mechanical properties and electrical conductivity of CuNi9Sn2 [PDF]

open access: yesMining and Metallurgy Engineering Bor
The interest in copper-based alloys with nickel and tin is constantly increasing. In this regard, certain tests were performed on CuNi9Sn2 alloy samples.
Ivanović Aleksandra   +3 more
doaj   +1 more source

Elongated Uvula [PDF]

open access: yesEar, Nose & Throat Journal, 2010
Tal, Marom, Yehudah, Roth, Udi, Cinamon
openaire   +2 more sources

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

The influence of the characteristics of breaking test units on the results of testing plastic properties of the wire RML

open access: yesЛитьë и металлургия, 2019
For metal products manufactured by hardware shops (metal cord, PML wire and side bronzed wire), the most important mechanical properties are those, that determine the strength, ductility and other characteristics of the materials.
N. A. Akunets
doaj   +1 more source

Cytosolic disproportionating enzyme2 is essential for pollen germination and pollen tube elongation in rice

open access: green, 2022
Liangke Chen   +6 more
openalex   +2 more sources

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