Results 91 to 100 of about 691,599 (315)

Microstructural evaluation and mechanical properties of 7075 aluminum alloy prepared by controlled diffusion solidification [PDF]

China Foundry, 2019
In the present work, 7075 aluminum alloy (Al-Zn-Mg-Cu) was produced by both conventional casting (CC) and controlled diffusion solidification (CDS) methods.
Xiong Yang, Yuan-dong Li, Xiao-mei Luo
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Synthetic transcription elongation factors license transcription across repressive chromatin

Science, 2017
Chemical control of transcription Friedreich's ataxia, a devastating neurodegenerative disease with no effective therapy, is caused by an expansion of intronic repeats and hence a reduced expression of the FXN gene. Erwin et al.
Graham S. Erwin, Matthew P. Grieshop, Asfa Ali, J. Qi, Matthew A. Lawlor, Deepak Kumar, I. Ahmad, A. McNally, N. Teider, Kathleen A. Worringer, Rajeev Sivasankaran, D. Syed, A. Eguchi, M. Ashraf, J. Jeffery, Mousheng Xu, Paul M. C. Park, H. Mukhtar, A. Srivastava, M. Faruq, J. Bradner, A. Ansari   +21 more
semanticscholar   +1 more source

Genetic and Molecular Regulation of Cotton Fiber Initiation and Elongation

Agronomy
Cotton fiber, a crucial and sustainable resource for global textile production, undergoes a complex five-stage developmental process, encompassing initiation, elongation, transition, secondary cell wall biosynthesis, and maturation.
Fang Bai, Jodi Scheffler
doaj   +1 more source

On the Relationship between Structural Quality Index and Fatigue Life Distributions in Aluminum Aerospace Castings

Metals, 2016
Tensile and fatigue testing results of D357 and B201 aluminum alloy aerospace castings reported in the literature have been reanalyzed. Yield strength–elongation bivariate data have been used as a measure of the structural quality of castings, and ...
Hüseyin Özdeş, Murat Tiryakioğlu
doaj   +1 more source

On elongations of QTAG-modules

Mathematical Sciences, 2013
Abstract Mehdi studied (ω+k)-projective QTAG-modules with the help of their submodules contained in H k (M) (the submodule generated by the elements of exponents at most k). These modules contain nice submodules N contained in H k (M) such that M/N is a direct sum ...
Alveera Mehdi, Fahad Sikander, Sabah A. R. K. Naji   +2 more
openaire   +2 more sources

Initiation with Elongator tRNAs [PDF]

Journal of Bacteriology, 2013
In all domains of life, initiator tRNA functions exclusively at the first step of protein synthesis while elongator tRNAs extend the polypeptide chain. Unique features of initiator tRNA enable it to preferentially bind the ribosomal P site and initiate translation.
Laasya, Samhita, Kai, Virumäe, Jaanus, Remme, Umesh, Varshney   +3 more
openaire   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Coupling of RNA polymerase II transcription elongation with pre-mRNA splicing

Journal of Molecular Biology, 2016
Pre-mRNA maturation frequently occurs at the same time and place as transcription by RNA polymerase II (pol II). The co-transcriptionality of mRNA processing has permitted the evolution of mechanisms that functionally couple transcription elongation with
Tassa K. Saldi, Michael A. Cortázar, R. Sheridan, D. Bentley   +3 more
semanticscholar   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source