Results 111 to 120 of about 531,808 (317)
FHOD1 coordinates actin filament and microtubule alignment to mediate cell elongation
, 2005 Diaphanous-related formins (DRFs) are actin nucleators that mediate rearrangements of the actin cytoskeleton downstream of specific Rho GTPases. The DRF Formin Homology 2 Domain containing 1 (FHOD1) interacts with the Rac1 GTPase and induces the ...
Muranyi, Walter +5 more
core +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Biomechanical analysis of ulnar nerve gliding and elongation: implications for nonsurgical ulnar nerve release in cubital tunnel syndrome [PDF]
Clinics in Shoulder and ElbowBackground Nonsurgical ulnar nerve release was developed for conservative treatment of cubital tunnel syndrome. Our objective in this study was to investigate the amount of ulnar nerve gliding and elongation during passive wrist, forearm, or elbow ...
Teruhisa Mihata +4 more
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Effect of Cytex on the Elongation of Inflorescence in Kyoho Grapevines
, 2014 為探討改善臺灣巨峰(Vitis uinifera L. × Vitis labruscana Bailey)葡萄花穗短小之方法，於民國81年2-3月間在臺中縣霧峰鄉及彰化縣大村鄉以Cytex於萌芽前展葉期及開花前5日處理，結果發現Cytex對葡萄花穗之伸長有促進作用，萌芽前之處理效果較萌芽後之處理顯著。The inflorescence elongation of Kyoho (Vitis vinifera L.
Yau-Shiang Yang +7 more
core
Microphase-separated structure and rheological properties of polyurethanes [PDF]
, 2008 A novel diisocyanate, 1,2-bisisocyanate ethoxyethane (TEGDI) whose backbone is ether bonds, was used for the preparation of polyurethane elastomers (PUEs).
小椎尾, 謙
core +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Table 2. FI SAZ vs Trunk Early and mid-elongation
, 2017 Table 2.
Constanza C. Macaya (4501006) +3 more
core +1 more source
Advanced Engineering Materials, EarlyView.This study demonstrates an efficient recycling route for out‐of‐spec AlSi10Mg atomized powders through compaction and arc remelting followed by suction casting. By correlating compaction load, cooling rate, and resulting microstructure, we show that intermediate pressures (50–80 kN) and rapid cooling refine dendrites, reduce porosity, and enhance ...
Mila Christy de Oliveira +4 more
wiley +1 more source