Results 1 to 10 of about 159,783 (279)

Peptide‐Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries [PDF]

Advanced Science
Peripheral nerve injury (PNI), commonly caused by various forms of trauma, may lead to numbness, muscle weakness, and even loss of motor and sensory function.
Zhiwei Zhao, Jianfeng Liu, Jincheng Li, Di Li, Jianxun Ding, Bin Liu   +5 more
doaj   +2 more sources

Elongating Effect of the Peptide AEDL on the Root of Nicotiana tabacum under Salinity

Plants, 2022
The overall survival of a plant depends on the development, growth, and functioning of the roots. Root development and growth are not only genetically programmed but are constantly influenced by environmental factors, with the roots adapting to such ...
Larisa I. Fedoreyeva, Ekaterina N. Baranova, Inn A. Chaban, Tatyana A. Dilovarova, Boris F. Vanyushin, Neonila V. Kononenko   +5 more
doaj   +1 more source

Medical Countermeasures against Ricin Intoxication

Toxins, 2023
Ricin toxin is a disulfide-linked glycoprotein (AB toxin) comprising one enzymatic A chain (RTA) and one cell-binding B chain (RTB) contained in the castor bean, a Ricinus species.
Christine Rasetti-Escargueil, Arnaud Avril   +1 more
doaj   +1 more source

Control of translation elongation in health and disease

Disease Models & Mechanisms, 2020
Regulation of protein synthesis makes a major contribution to post-transcriptional control pathways. During disease, or under stress, cells initiate processes to reprogramme protein synthesis and thus orchestrate the appropriate cellular response. Recent
John R. P. Knight, Gavin Garland, Tuija Pöyry, Emma Mead, Nikola Vlahov, Aristeidis Sfakianos, Stefano Grosso, Fabio De-Lima-Hedayioglu, Giovanna R. Mallucci, Tobias von der Haar, C. Mark Smales, Owen J. Sansom, Anne E. Willis   +12 more
doaj   +1 more source

A LytM-Domain Factor, ActS, Functions in Two Distinctive Peptidoglycan Hydrolytic Pathways in E. coli

Frontiers in Microbiology, 2022
Bacterial cell wall contains peptidoglycan (PG) to protect the cells from turgor and environmental stress. PG consists of polymeric glycans cross-linked with each other by short peptide chains and forms an elastic mesh-like sacculus around the ...
Pavan Kumar Chodisetti, Raj Bahadur, R. N. Amrutha, Manjula Reddy   +3 more
doaj   +1 more source

Translation factor accelerating peptide bond formation on the ribosome: EF-P and eIF5A as entropic catalysts and a potential drug targets

BBA Advances, 2023
Elongation factor P (EF-P) and its eukaryotic homolog eIF5A are auxiliary translation factors that facilitate peptide bond formation when several sequential proline (Pro) residues are incorporated into the nascent chain.
Vitalii Mudryi, Frank Peske, Marina Rodnina   +2 more
doaj   +1 more source

Kinetics of initiating polypeptide elongation in an IRES-dependent system

eLife, 2016
The intergenic IRES of Cricket Paralysis Virus (CrPV-IRES) forms a tight complex with 80S ribosomes capable of initiating the cell-free synthesis of complete proteins in the absence of initiation factors. Such synthesis raises the question of what effect
Haibo Zhang, Martin Y Ng, Yuanwei Chen, Barry S Cooperman   +3 more
doaj   +1 more source

Atrioventricular Conduction Abnormalities in Multisystem Inflammatory Syndrome in Children

Case Reports in Pediatrics, 2021
Cardiac manifestations in multisystem inflammatory syndrome in children (MIS-C) can include coronary artery aneurysms, left ventricular systolic dysfunction, and electrocardiographic disturbances.
Carlos A. Carmona, Fatma Levent, Kelvin Lee, Bhavya Trivedi   +3 more
doaj   +1 more source

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. [PDF]

, 2013
Human positive transcription elongation factor b (P-TEFb) phosphorylates RNA polymerase II and regulatory proteins to trigger elongation of many gene transcripts.
Alber, Tom, Bao, Katherine, Birnberg, Andrew, Chou, Seemay, Krogan, Nevan J, Schulze-Gahmen, Ursula, Upton, Heather, Zhou, Qiang   +7 more
core   +1 more source

Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2

Toxins, 2016
Ricin is a type 2 ribosome-inactivating protein (RIP), containing a catalytic A chain and a lectin-like B chain. It inhibits protein synthesis by depurinating the N-glycosidic bond at α-sarcin/ricin loop (SRL) of the 28S rRNA, which thereby prevents the ...
Wei-Wei Shi, Yun-Sang Tang, See-Yuen Sze, Zhen-Ning Zhu, Kam-Bo Wong, Pang-Chui Shaw   +5 more
doaj   +1 more source