Peptide‐Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries [PDF]
Peripheral nerve injury (PNI), commonly caused by various forms of trauma, may lead to numbness, muscle weakness, and even loss of motor and sensory function.
Zhiwei Zhao +5 more
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N-terminal formylmethionine as a degron and a specific signal in proteostasis and stress adaptation [PDF]
N-terminal (Nt) methionine formylation, once thought restricted to bacteria and organelles, is now recognized as a stress-inducible initiator modification in the eukaryotic cytosol.
Chang-Seok Lee +2 more
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Elongating Effect of the Peptide AEDL on the Root of Nicotiana tabacum under Salinity
The overall survival of a plant depends on the development, growth, and functioning of the roots. Root development and growth are not only genetically programmed but are constantly influenced by environmental factors, with the roots adapting to such ...
Larisa I. Fedoreyeva +5 more
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Cholesteryl esters are bound by a peptide-initiation and a peptide-elongation factor [PDF]
Significantly higher quantities of cholesteryl 14-methylhexadecanoate than of cholesteryl laurate and cholesteryl palmitate are bound by a homogeneous peptide-initiation factor and purified peptide-elongation factor 1. Cholesteryl 14-methylhexadecanoate may function as a specific allosteric modifier changing the conformation of protein synthesis ...
Z, Tuhácková, J, Hradec
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Medical Countermeasures against Ricin Intoxication
Ricin toxin is a disulfide-linked glycoprotein (AB toxin) comprising one enzymatic A chain (RTA) and one cell-binding B chain (RTB) contained in the castor bean, a Ricinus species.
Christine Rasetti-Escargueil +1 more
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Control of translation elongation in health and disease
Regulation of protein synthesis makes a major contribution to post-transcriptional control pathways. During disease, or under stress, cells initiate processes to reprogramme protein synthesis and thus orchestrate the appropriate cellular response. Recent
John R. P. Knight +12 more
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Mitochondrial peptide chain elongation factors from Neurospora crassa [PDF]
Two complementary peptide chain elongation factors (G and T) have been isolated from a mitochondrial 100,000 g supernatant. Both factors are specific for 70 S ribosomes and can be crossed with T and G factors from E. coli.
Grandi, Maria, Küntzel, Hans
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Further Evidence that Elongation Factor 1 Remains Bound to Ribosomes during Peptide Chain Elongation [PDF]
This paper describes three types of experiments which indicate that the binding sites for elongation factor 1 (EF‐1) and elongation factor 2 (EF‐2) on ascites cell ribosomes are not identical and perhaps not even overlapping. The experimental evidence presented includes direct competitive binding of labeled elongation factors to ribosomes as well as ...
H, Grasmuk, R D, Nolan, J, Drews
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Bacterial cell wall contains peptidoglycan (PG) to protect the cells from turgor and environmental stress. PG consists of polymeric glycans cross-linked with each other by short peptide chains and forms an elastic mesh-like sacculus around the ...
Pavan Kumar Chodisetti +3 more
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Origin of the ribosome specific factors responsible for peptide chain elongation in yeast [PDF]
The factors responsible for polypeptide chain elongation are specific for ribosomes of either the 70 S or the 80 S type [l--4]. Two different sets of elongation factors, one specific for 70 S ribosomes and one for 80 S ribosomes, are present in eukaryotic organisms: in Ne ...
Parisi, Bruno, Cella, Rino
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