Results 11 to 20 of about 159,783 (279)
Cholesteryl esters are bound by a peptide-initiation and a peptide-elongation factor [PDF]
Biochemical Journal, 1980 Significantly higher quantities of cholesteryl 14-methylhexadecanoate than of cholesteryl laurate and cholesteryl palmitate are bound by a homogeneous peptide-initiation factor and purified peptide-elongation factor 1. Cholesteryl 14-methylhexadecanoate may function as a specific allosteric modifier changing the conformation of protein synthesis ...
Z, Tuhácková, J, Hradec
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Mitochondrial peptide chain elongation factors from Neurospora crassa [PDF]
FEBS Letters, 1970 Two complementary peptide chain elongation factors (G and T) have been isolated from a mitochondrial 100,000 g supernatant. Both factors are specific for 70 S ribosomes and can be crossed with T and G factors from E. coli.
Grandi, Maria, Küntzel, Hans
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Further Evidence that Elongation Factor 1 Remains Bound to Ribosomes during Peptide Chain Elongation [PDF]
European Journal of Biochemistry, 1977 This paper describes three types of experiments which indicate that the binding sites for elongation factor 1 (EF‐1) and elongation factor 2 (EF‐2) on ascites cell ribosomes are not identical and perhaps not even overlapping. The experimental evidence presented includes direct competitive binding of labeled elongation factors to ribosomes as well as ...
H, Grasmuk, R D, Nolan, J, Drews
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Origin of the ribosome specific factors responsible for peptide chain elongation in yeast [PDF]
FEBS Letters, 1971 The factors responsible for polypeptide chain elongation are specific for ribosomes of either the 70 S or the 80 S type [l--4]. Two different sets of elongation factors, one specific for 70 S ribosomes and one for 80 S ribosomes, are present in eukaryotic organisms: in Ne ...
Parisi, Bruno, Cella, Rino
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Regulation of the activity of eukaryotic peptide elongation factor 1 by autocatalytic phosphorylation [PDF]
European Journal of Biochemistry, 1985 Highly purified peptide elongation factor 1 from rabbit reticulocytes liberates the terminal phosphate from [γ‐32P]GTP and incorporates it into its own protein. Approximately one phosphate residue becomes bound by one molecule of the factor. Only the eEF‐1α subunit of the factor (Mr 53000) becomes phosphorylated as revealed by polyacrylamide gel ...
Z, Tuhácková +2 more
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Decreased activity of peptide-elongation factors after treatment with cholesterol esterase [PDF]
Biochemical Journal, 1978 1. Peptide-elongation factors were purified from rat liver and treated with cholesterol esterase and phospholipase A2 immobilized on Sepharose 4B. 2. Binding of L-[3H]-phenylalanyl-tRNA to 40S ribosomal subunits was decreased by approx. 70% and to polyribosomes by 30% in the presence of the binding factor incubated with cholesterol esterase.
J, Hradec, Z, Tuhácková, Z, Dusek
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Frontiers in Microbiology, 2021 Translation is an important step in gene expression. Initiation of translation is rate-limiting, and it is phylogenetically more diverse than elongation or termination. Bacteria contain only three initiation factors. In stark contrast, eukaryotes contain
Franziska Schramm +3 more
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Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription. [PDF]
, 2020 Deregulated expression of MYC induces a dependence on the NUAK1 kinase, but the molecular mechanisms underlying this dependence have not been fully clarified.
Ade, C.P. +18 more
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A stochastic model for simulating ribosome kinetics in vivo.
PLoS Computational Biology, 2020 Computational modelling of in vivo protein synthesis is highly complicated, as it requires the simulation of ribosomal movement over the entire transcriptome, as well as consideration of the concentration effects from 40+ different types of tRNAs and ...
Eric Charles Dykeman
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Frontiers in Plant Science, 2020 Phytosulfokines (PSKs) are plant peptide growth factors that participate in multiple biological processes, including cell elongation and immune signaling. However, little is known about PSKs in Rosaceae species.
Xiaobing Kou +5 more
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