Results 31 to 40 of about 82,531 (244)

Investigation of Parameters that Affect Resin Swelling in Green Solvents

open access: yesChemistryOpen, 2020
The influence of various physical and chemical factors on the swelling of polystyrene and PEG based resins in greener organic solvents has been systematically investigated.
Chidi Amadi‐Kamalu   +10 more
doaj   +1 more source

Pinning Down the Transcription: A Role for Peptidyl-Prolyl cis-trans Isomerase Pin1 in Gene Expression

open access: yesFrontiers in Cell and Developmental Biology, 2020
Pin1 is a peptidyl-prolyl cis-trans isomerase that specifically binds to a phosphorylated serine or threonine residue preceding a proline (pSer/Thr-Pro) motif and catalyzes the cis-trans isomerization of proline imidic peptide bond, resulting in ...
Xiangming Hu   +2 more
doaj   +1 more source

Epigallocatechine-3-gallate Inhibits the Adipogenesis of Human Mesenchymal Stem Cells via the Regulation of Protein Phosphatase-2A and Myosin Phosphatase

open access: yesCells, 2022
Epigallocatechin-3-gallate (EGCG) has widespread effects on adipocyte development. However, the molecular mechanisms of EGCG are not fully understood. We investigate the adipogenic differentiation of human-derived mesenchymal stem cells, including lipid ...
Bálint Bécsi   +4 more
doaj   +1 more source

Improved functionality and potency of next generation BinMLV viral vectors toward safer gene therapy

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
To develop safer retroviral murine leukemia virus (MLV)-based vectors, we previously mutated and re-engineered the MLV integrase: the W390A mutation abolished the interaction with its cellular tethering factors, BET proteins, and a retargeting peptide ...
Dominique Van Looveren   +4 more
doaj   +1 more source

Specific peptide-activated proteolytic cleavage of Escherichia coli elongation factor Tu [PDF]

open access: yesProceedings of the National Academy of Sciences, 1998
Phage exclusion is a form of programmed cell death in prokaryotes in which death is triggered by infection with phage, a seemingly altruistic response that limits multiplication of the phage and its spread through the population. One of the best-characterized examples of phage exclusion is the exclusion of T-even phages such as T4 ...
T, Georgiou   +7 more
openaire   +2 more sources

Spatial Distribution and Ribosome-Binding Dynamics of EF-P in Live Escherichia coli

open access: yesmBio, 2017
In vitro assays find that ribosomes form peptide bonds to proline (Pro) residues more slowly than to other residues. Ribosome profiling shows that stalling at Pro-Pro-X triplets is especially severe but is largely alleviated in Escherichia coli by the ...
Sonisilpa Mohapatra   +4 more
doaj   +1 more source

Recent insights into eukaryotic translation initiation factors 5A1 and 5A2 and their roles in human health and disease

open access: yesCancer Cell International, 2020
The eukaryotic translation initiation factor 5A1 (eIF5A1) and its homolog eIF5A2 are the only two human proteins containing the unique post-translational modification–hypusination, which is essential for the function of these two proteins.
Gao-Qi Wu, Yan-Ming Xu, Andy T. Y. Lau
doaj   +1 more source

Aminoacyl-tRNA-charged eukaryotic elongation factor 1A is the bona fide substrate for Legionella pneumophila effector glucosyltransferases. [PDF]

open access: yesPLoS ONE, 2011
Legionella pneumophila, which is the causative organism of Legionnaireś disease, translocates numerous effector proteins into the host cell cytosol by a type IV secretion system during infection.
Tina Tzivelekidis   +8 more
doaj   +1 more source

Microbial Proteins in Stomach Biopsies Associated with Gastritis, Ulcer, and Gastric Cancer

open access: yesMolecules, 2022
(1) Background: Gastric cancer (GC) is the fourth leading cause of cancer-related deaths worldwide. Helicobacter pylori infection is a major risk factor, but other microbial species may also be involved.
Shahid Aziz   +4 more
doaj   +1 more source

Insight Into Pituitary lncRNA and mRNA at Two Estrous Stages in Small Tail Han Sheep With Different FecB Genotypes

open access: yesFrontiers in Endocrinology, 2022
The pituitary is a remarkably dynamic organ with roles in hormone (FSH and LH) synthesis and secretion. In animals with the FecB (fecundity Booroola) mutation, the pituitary experiences hormone fluctuations during the follicular–luteal transition, which ...
Si Chen   +8 more
doaj   +1 more source

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