Results 21 to 30 of about 82,531 (244)
BBA Advances, 2023 Elongation factor P (EF-P) and its eukaryotic homolog eIF5A are auxiliary translation factors that facilitate peptide bond formation when several sequential proline (Pro) residues are incorporated into the nascent chain.
Vitalii Mudryi +2 more
doaj +1 more source
Regulation of the activity of eukaryotic peptide elongation factor 1 by autocatalytic phosphorylation [PDF]
European Journal of Biochemistry, 1985 Highly purified peptide elongation factor 1 from rabbit reticulocytes liberates the terminal phosphate from [γ‐32P]GTP and incorporates it into its own protein. Approximately one phosphate residue becomes bound by one molecule of the factor. Only the eEF‐1α subunit of the factor (Mr 53000) becomes phosphorylated as revealed by polyacrylamide gel ...
Z, Tuhácková +2 more
openaire +2 more sources
Kinetics of initiating polypeptide elongation in an IRES-dependent system
eLife, 2016 The intergenic IRES of Cricket Paralysis Virus (CrPV-IRES) forms a tight complex with 80S ribosomes capable of initiating the cell-free synthesis of complete proteins in the absence of initiation factors. Such synthesis raises the question of what effect
Haibo Zhang +3 more
doaj +1 more source
Atrioventricular Conduction Abnormalities in Multisystem Inflammatory Syndrome in Children
Case Reports in Pediatrics, 2021 Cardiac manifestations in multisystem inflammatory syndrome in children (MIS-C) can include coronary artery aneurysms, left ventricular systolic dysfunction, and electrocardiographic disturbances.
Carlos A. Carmona +3 more
doaj +1 more source
Decreased activity of peptide-elongation factors after treatment with cholesterol esterase [PDF]
Biochemical Journal, 1978 1. Peptide-elongation factors were purified from rat liver and treated with cholesterol esterase and phospholipase A2 immobilized on Sepharose 4B. 2. Binding of L-[3H]-phenylalanyl-tRNA to 40S ribosomal subunits was decreased by approx. 70% and to polyribosomes by 30% in the presence of the binding factor incubated with cholesterol esterase.
J, Hradec, Z, Tuhácková, Z, Dusek
openaire +2 more sources
Toxins, 2016 Ricin is a type 2 ribosome-inactivating protein (RIP), containing a catalytic A chain and a lectin-like B chain. It inhibits protein synthesis by depurinating the N-glycosidic bond at α-sarcin/ricin loop (SRL) of the 28S rRNA, which thereby prevents the ...
Wei-Wei Shi +5 more
doaj +1 more source
Frontiers in Plant Science, 2020 Phytosulfokines (PSKs) are plant peptide growth factors that participate in multiple biological processes, including cell elongation and immune signaling. However, little is known about PSKs in Rosaceae species.
Xiaobing Kou +5 more
doaj +1 more source
Frontiers in Microbiology, 2021 Translation is an important step in gene expression. Initiation of translation is rate-limiting, and it is phylogenetically more diverse than elongation or termination. Bacteria contain only three initiation factors. In stark contrast, eukaryotes contain
Franziska Schramm +3 more
doaj +1 more source
A stochastic model for simulating ribosome kinetics in vivo.
PLoS Computational Biology, 2020 Computational modelling of in vivo protein synthesis is highly complicated, as it requires the simulation of ribosomal movement over the entire transcriptome, as well as consideration of the concentration effects from 40+ different types of tRNAs and ...
Eric Charles Dykeman
doaj +1 more source
Bacterial Extracellular DNA Promotes β-Amyloid Aggregation
Microorganisms, 2021 Alzheimer’s disease is associated with prion-like aggregation of the amyloid β (Aβ) peptide and the subsequent accumulation of misfolded neurotoxic aggregates in the brain.
George Tetz, Victor Tetz
doaj +1 more source