Results 21 to 30 of about 159,783 (279)

Bacterial Extracellular DNA Promotes β-Amyloid Aggregation

Microorganisms, 2021
Alzheimer’s disease is associated with prion-like aggregation of the amyloid β (Aβ) peptide and the subsequent accumulation of misfolded neurotoxic aggregates in the brain.
George Tetz, Victor Tetz
doaj   +1 more source

Tomato EF-Tsmt, a functional mitochondrial translation elongation factor from higher plants [PDF]

, 2003
Ethylene-induced ripening in tomato (Lycopersicon esculentum) resulted in the accumulation of a transcript designated LeEF-Tsmt that encodes a protein with significant homology to bacterial Ts translational elongation factor (EF-Ts).
Benichou, Mohamed, Bouzayen, Mondher, Chaves, Ana, Delalande, Corinne, Jauneau, Alain, Latché, Alain, Li, Zhengguo, Pech, Jean-Claude, Spremulli, Linda L., Tournier, Barthélémy, Zegzouti, Hicham   +10 more
core   +2 more sources

Epigallocatechine-3-gallate Inhibits the Adipogenesis of Human Mesenchymal Stem Cells via the Regulation of Protein Phosphatase-2A and Myosin Phosphatase

Cells, 2022
Epigallocatechin-3-gallate (EGCG) has widespread effects on adipocyte development. However, the molecular mechanisms of EGCG are not fully understood. We investigate the adipogenic differentiation of human-derived mesenchymal stem cells, including lipid ...
Bálint Bécsi, Zoltán Kónya, Anita Boratkó, Katalin Kovács, Ferenc Erdődi   +4 more
doaj   +1 more source

Symbiotic outcome modified by the diversification from 7 to over 700 nodule specific cysteine rich peptides [PDF]

, 2020
Legume-rhizobium symbiosis represents one of the most successfully co-evolved mutualisms. Within nodules, the bacterial cells undergo distinct metabolic and morphological changes and differentiate into nitrogen-fixing bacteroids.
Achom, Mingkee, Gifford, Miriam L., Lagunas, Beatriz, Roy, Proyash, Wilkinson, Helen   +4 more
core   +1 more source

Investigation of Parameters that Affect Resin Swelling in Green Solvents

ChemistryOpen, 2020
The influence of various physical and chemical factors on the swelling of polystyrene and PEG based resins in greener organic solvents has been systematically investigated.
Chidi Amadi‐Kamalu, Holly Clarke, Matthew McRobie, James Mortimer, Prof. Michael North, Yanrui Ran, Dr. Anne Routledge, Dani Sibbald, Matthew Tickias, Kai Tse, Helen Willway   +10 more
doaj   +1 more source

Pinning Down the Transcription: A Role for Peptidyl-Prolyl cis-trans Isomerase Pin1 in Gene Expression

Frontiers in Cell and Developmental Biology, 2020
Pin1 is a peptidyl-prolyl cis-trans isomerase that specifically binds to a phosphorylated serine or threonine residue preceding a proline (pSer/Thr-Pro) motif and catalyzes the cis-trans isomerization of proline imidic peptide bond, resulting in ...
Xiangming Hu, Lin-Feng Chen, Lin-Feng Chen   +2 more
doaj   +1 more source

An in vivo control map for the eukaryotic mRNA translation machinery [PDF]

, 2013
Rate control analysis defines the in vivo control map governing yeast protein synthesis and generates an extensively parameterized digital model of the translation pathway.
Amy Claydon, Hans Westerhoff, Helena Firczuk, John Duncan, John EG McCarthy, Jürgen Pahle, Kemper WM, Mathews MB, Pedro Mendes, Robert Beynon, Sambrook J, Shichina Kannambath, Valentini SR   +12 more
core   +3 more sources

Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex [PDF]

, 2018
ELL family transcription factors activate the overall rate of RNA polymerase II (Pol II) transcription elongation by binding directly to Pol II and suppressing its tendency to pause.
Alonso-Nunez, Bahler, Bahler, Banks, Buchan, Cairns, Charles AS Banks, Chou, Christopher W Seidel, Coudreuse, Dana M Gibbon, Elmendorf, Florens, Garg, He, He, Joan W Conaway, Kim, Kimura, Kimura, Kitts, Kong, Langmead, Laurence A Florens, Li, Lin, Luo, Luo, Michael P Washburn, Miller, Monahan, Nimisha Sharma, Oliva, Preeti Dabas, Quinlan, Robinson, Ronald C Conaway, Rustici, Shilatifard, Shilatifard, Simone, Simone, Sneha Gopalan, Sobhian, Suarez, Szklarczyk, Tabb, Takahashi, Thorvaldsdottir, Tsai, Ward, Washburn, Ying Zhang, Yokoyama, Zhang   +54 more
core   +1 more source

Specific peptide-activated proteolytic cleavage of Escherichia coli elongation factor Tu [PDF]

Proceedings of the National Academy of Sciences, 1998
Phage exclusion is a form of programmed cell death in prokaryotes in which death is triggered by infection with phage, a seemingly altruistic response that limits multiplication of the phage and its spread through the population. One of the best-characterized examples of phage exclusion is the exclusion of T-even phages such as T4 by the ...
T, Georgiou, Y N, Yu, S, Ekunwe, M J, Buttner, A, Zuurmond, B, Kraal, C, Kleanthous, L, Snyder   +7 more
openaire   +2 more sources

Improved functionality and potency of next generation BinMLV viral vectors toward safer gene therapy

Molecular Therapy: Methods & Clinical Development, 2021
To develop safer retroviral murine leukemia virus (MLV)-based vectors, we previously mutated and re-engineered the MLV integrase: the W390A mutation abolished the interaction with its cellular tethering factors, BET proteins, and a retargeting peptide ...
Dominique Van Looveren, Giorgia Giacomazzi, Irina Thiry, Maurilio Sampaolesi, Rik Gijsbers   +4 more
doaj   +1 more source