Rational design and preclinical evaluation of elastin-like polypeptide micelle nanoparticles for drug delivery [PDF]
Frontiers in Bioengineering and BiotechnologyElastin-like polypeptide (ELP) micelle nanoparticles have emerged as versatile and tunable platforms for drug delivery across diseases. These bio-inspired and thermo-responsive polymers typically produced recombinantly in E.coli or yeast offer great ...
Abdulhakim Tofik +3 more
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Photothermal-Responsive Phase Transition of Proteoliposomes for Heat Shock Protein Sequestering against Cancer Thermoresistance [PDF]
ResearchPhotothermal therapy (PTT) has garnered considerable attention for its noninvasive and localized treatment advantages. However, in response to PTT-induced hyperthermia, cancer cells increase the expression level of heat shock proteins (HSPs) and activate
Kai Cheng +6 more
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Frequency of Clinically Relevant Drug–Drug Interactions Between Tyrosine Kinase Inhibitors and Proton Pump Inhibitors in Patients With Cancer Using Real‐World Data [PDF]
Basic Clin Pharmacol ToxicolABSTRACT Background Proton pump inhibitors (PPIs) raise stomach pH, leading to reduced bioavailability of many tyrosine kinase inhibitors (TKIs), thereby affecting treatment outcomes. To what extent this interaction occurs in clinical practice remains underexplored.
van Elp G +5 more
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Integrative learning approach in ESP/ELP: Theoretical framework of intradisciplinary, multidisciplinary, interdisciplinary, and transdisciplinary integration [PDF]
Zbornik Radova Pravnog Fakulteta u Nišu, 2020 In English for Specific Purposes (ESP), Integrative Learning has been used in many contexts as a conceptual and structural framework for designing holistic and authentic learning experiences.
Ignjatović Gordana
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Revista de Psicología, 2021 A partir de hitos en la historia de la clínica se enmarca el surgimiento del psicoanálisis como un discurso nuevo acerca de la causa de los padecimientos humanos (neurosis y psicosis) cuyo nódulo afecta a la identidad, a la cuestión del ser.
Vilma Coccoz
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Frontiers in Immunology, 2022 There is growing concern about the toxicity of colloidal aluminum salts used as adjuvants in subcutaneous allergen immunotherapy (SCIT). Therefore, alternative adjuvants and delivery systems are being explored to replace alum in SCIT. We applied micellar
Jolinde van Strien +16 more
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Foods, 2023 In the present study, the immuno-enhancing effect of Eucommia ulmoides leaf polysaccharide (ELP) was investigated in immunosuppressed mice induced by cyclophosphamide (CTX). To evaluate the immune enhancement mechanism of ELP, the immunoregulation effect
Enhui Cui +7 more
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Relationship between effective lens position and axial position of a thick intraocular lens. [PDF]
PLoS ONE, 2018 PurposeTo discuss the impact of intraocular lens-(IOL)-power, IOL-thickness, IOL-shape, corneal power and effective lens position (ELP) on the distance between the anterior IOL vertex (ALP) of a thick IOL and the ELP of its thin lens equivalent.MethodsWe
Simon Schröder, Achim Langenbucher
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Elastin-like Polypeptide Hydrogels for Tunable, Sustained Local Chemotherapy in Malignant Glioma
Pharmaceutics, 2022 Glioblastoma (GBM) is a primary brain tumor that carries a dismal prognosis, which is primarily attributed to tumor recurrence after surgery and resistance to chemotherapy. Since the tumor recurrence appears near the site of surgical resection, a concept
Sonja Dragojevic +4 more
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Elastin-like polypeptide modified silk fibroin porous scaffold promotes osteochondral repair
Bioactive Materials, 2021 Silk fibroin (SF) is considered biocompatible and biodegradable for osteochondral repair. However, it lacks a bioactive domain for cell adhesion, proliferation and differentiation, limiting its therapeutic efficacy.
Zhuoyue Chen +5 more
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