Results 31 to 40 of about 11,842 (207)

A dose-escalating toxicology study of the candidate biologic ELP-VEGF

open access: yesScientific Reports, 2021
Vascular Endothelial Growth Factor (VEGF), a key mediator of angiogenesis and vascular repair, is reduced in chronic ischemic renal diseases, leading to microvascular rarefaction and deterioration of renal function.
Jamarius P. Waller   +4 more
doaj   +1 more source

Thermodynamic Parameters of Berberine with Kolliphor Mixtures Adsorption and Micellization

open access: yesMolecules, 2023
The poor solubility of berberine (Ber) in water limits its practical use. Its solubility can be increased, among other ways, by the addition of surfactants.
Magdalena Szaniawska   +3 more
doaj   +1 more source

Molecular Size Modulates Pharmacokinetics, Biodistribution, and Renal Deposition of the Drug Delivery Biopolymer Elastin-like Polypeptide

open access: yesScientific Reports, 2018
Elastin-like polypeptides (ELP) are engineered proteins that consist of repetitions of a five amino acid motif, and their composition is easily modified to adjust their physical properties and attach therapeutics.
Marija Kuna   +3 more
doaj   +1 more source

A highly-sensitive genetically encoded temperature indicator exploiting a temperature-responsive elastin-like polypeptide

open access: yesScientific Reports, 2021
Genetically encoded temperature indicators (GETIs) allow for real-time measurement of subcellular temperature dynamics in live cells. However, GETIs have suffered from poor temperature sensitivity, which may not be sufficient to resolve small heat ...
Cong Quang Vu   +3 more
doaj   +1 more source

Enhancing the ELP for the 21st Century

open access: yes, 2009
The Council of Europe’s European Language Portfolio (ELP) was originally designed as a paper based document in three distinct parts (Passport, Biography, Dossier).
Tita, Beaven   +2 more
core   +5 more sources

Erosive lichen planus: an unmet disease burden

open access: yesFrontiers in Medicine
ObjectivesTo explore the demographic and clinical profile of erosive lichen planus (ELP) across multiple ethnicities within a single cohort, deepening our understanding of disease severity, progression and outcomes.MethodsA longitudinal retrospective ...
John H. Macken   +7 more
doaj   +1 more source

Implementation of European Language Portfolio in Lithuania: Problems and Implications

open access: yesVerbum, 2011
The European Language Portfolio (ELP) has been one of the biggest language education projects of the last decade in Europe. Lithuania has invested considerable finances and effort to exploit the benefits of the ELP. There have been a number of Portfolios
Zita Mažuolienė
doaj   +1 more source

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

open access: yesAdvanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu   +7 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Learning Moisture‐Induced Damage From Vision: Diffusion Models for Real‐Time Monitoring of Additive Manufacturing Processes

open access: yesAdvanced Science, EarlyView.
We introduce a vision‐based real‐time monitoring system for additive manufacturing that detects subtle moisture‐induced degradation via a diffusion model‐based framework. The approach enables nondestructive assessment of moisture‐induced damage level and mechanical performance and establishes a practical route toward more intelligent, reliable, and ...
Jiyoung Jung   +4 more
wiley   +1 more source

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