Results 51 to 60 of about 11,842 (207)

Investigation of characteristics as endodontic sealer of novel experimental elastin-like polypeptide-based mineral trioxide aggregate

Scientific Reports, 2021
Although mineral trioxide aggregates (MTA) have been adopted as an endodontic sealer because of excellent sealing effect and bioactive property and been modified with improvement of its characteristics, the developed MTA sealers have not yet satisfied ...
Hyun-Jung Kim, Ji-Hyun Jang, Sun-Young Kim   +2 more
doaj   +1 more source

Host Cell Protein Challenges in Antibody Processing: Insights Into Persistence and Mitigation Strategies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Persistence of HCPs remains a major purification challenge in biopharmaceutical manufacturing with direct consequences for product quality, patient safety, and regulatory compliance. Over the last two decades, deeper insights into the mechanisms driving HCP persistence have clarified why certain proteins evade removal during purification ...
Younghoon Oh, Andrew Cooke, Harshal Soni, Susan Liu, Mamadou Bah, Brianna Bellis, Laura Smith, Michael Capaldi, Nicholas Levy, Erik Wilhelm, Kristopher Barnthouse   +10 more
wiley   +1 more source

Elastin-Like Protein, with Statherin Derived Peptide, Controls Fluorapatite Formation and Morphology

Frontiers in Physiology, 2017
The process of enamel biomineralization is multi-step, complex and mediated by organic molecules. The lack of cells in mature enamel leaves it unable to regenerate and hence novel ways of growing enamel-like structures are currently being investigated ...
Kseniya Shuturminska, Kseniya Shuturminska, Nadezda V. Tarakina, Nadezda V. Tarakina, Helena S. Azevedo, Helena S. Azevedo, Helena S. Azevedo, Andrew J. Bushby, Andrew J. Bushby, Alvaro Mata, Alvaro Mata, Alvaro Mata, Paul Anderson, Maisoon Al-Jawad, Maisoon Al-Jawad   +14 more
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Antibodies Purification Using ELP-zz Domain Fusions [PDF]

, 2011
Antibodies are immune system&ndashrelated proteins called immunoglobulins (IgGs) which have applications for medical diagnostics and research. However, their purification from different sources has always been a challenge because of low antibody ...
CHAUDHARY, GARIMA
core   +1 more source

The mammary gland-specific marsupial ELP and eutherian CTI share a common ancestral gene

BMC Evolutionary Biology, 2012
Background The marsupial early lactation protein (ELP) gene is expressed in the mammary gland and the protein is secreted into milk during early lactation (Phase 2A).
Pharo Elizabeth A, De Leo Alison A, Renfree Marilyn B, Thomson Peter C, Lefèvre Christophe M, Nicholas Kevin R   +5 more
doaj   +1 more source

Characterization of Graphs Without Even F $F$‐Orientations

Journal of Graph Theory, EarlyView.
ABSTRACT A graph G $G$ is 1‐extendable if every edge belongs to at least one 1‐factor of G $G$. Let G $G$ be a graph with a 1‐factor F $F$. Then an even (odd) F $F$ ‐orientation of G $G$ is an orientation in which each F $F$‐alternating cycle has exactly an even (odd) number of edges directed in the same fixed direction around the cycle.
Marién Abreu, Domenico Labbate, Federico Romaniello, John Sheehan   +3 more
wiley   +1 more source

Controlling Release Kinetics of an Adjuvant from a Depot Improves the Efficacy of Local Immunotherapy in Metastatic Cancer

Advanced Science
Biomaterials can improve cancer immunotherapies by controlling their release and thereby optimizing their time‐dependent engagement of the immune system.
Joshua J. Milligan, Rachel L. Strader, Arunangshu Chakrabarty, Max Ney, Parul Sirohi, Jonathan C. Su, Anastasia K. Varanko, Yulia Shmidov, Kalina Tsolova, Cassio Mendes Fontes, Anna Finkelstein, Rohinee Mattikalli, Yun‐Xing Wang, Lixin Fan, Xinghai Li, Smita K. Nair, Ashutosh Chilkoti   +16 more
doaj   +1 more source

Lichen planus with dysphagia: an interdisciplinary, monocentric study of quality of life and depression

Frontiers in Medicine
BackgroundLichen planus (LP) is an inflammatory condition affecting skin and mucous membranes. Esophageal LP (ELP) is an underrecognized form causing dysphagia, with significant potential impact on patient quality of life.ObjectiveTo comprehensively ...
Rebecca Diehl, Annegrit Decker, Annette Schmitt-Graeff, Wolfgang Kreisel, Franziska Schauer   +4 more
doaj   +1 more source