Results 61 to 70 of about 59,650 (256)

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

Chemistry – A European Journal, EarlyView.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami, Hikari Ozawa, Sohei Ito   +2 more
wiley   +1 more source

Rational design and preclinical evaluation of elastin-like polypeptide micelle nanoparticles for drug delivery

Frontiers in Bioengineering and Biotechnology
Elastin-like polypeptide (ELP) micelle nanoparticles have emerged as versatile and tunable platforms for drug delivery across diseases. These bio-inspired and thermo-responsive polymers typically produced recombinantly in E.coli or yeast offer great ...
Abdulhakim Tofik, Yuwei Zhang, Cassandra Volpe, Jing Wang   +3 more
doaj   +1 more source

The mammary gland-specific marsupial ELP and eutherian CTI share a common ancestral gene

BMC Evolutionary Biology, 2012
Background The marsupial early lactation protein (ELP) gene is expressed in the mammary gland and the protein is secreted into milk during early lactation (Phase 2A).
Pharo Elizabeth A, De Leo Alison A, Renfree Marilyn B, Thomson Peter C, Lefèvre Christophe M, Nicholas Kevin R   +5 more
doaj   +1 more source

Automated Feedback for 'Fill in the Gap' Programming Exercises [PDF]

, 2005
Timely feedback is a vital component in the learning process. It is especially important for beginner students in Information Technology since many have not yet formed an effective internal model of a computer that they can use to construct viable ...
Bancroft, Peter, Roe, Paul, Truong, Dinh
core   +1 more source

Interference and Bandwidth Adjusted (ETX) in Wireless Multi-hop Networks

, 2010
In this paper, we propose a new quality link metric, interference and bandwidth adjusted ETX (IBETX) for wireless multi-hop networks. As MAC layer affects the link performance and consequently the route quality, the metric therefore, tackles the issue by
Bibi, Ayesha, Djouani, Karim, Javaid, Nadeem   +2 more
core   +1 more source

New Pedagogical Models Facilitated by Technology [PDF]

, 2013
This paper discusses the outcome of research conducted to assess the effectiveness of Work-Based Learning (WBL) from the perspective of stakeholders. WBL has increasingly become an area of interest for the higher education (HE) sector. It can support the
Barriere, Nicolas, Boggs, Steven E., Brejnholt, Nicolai F., Hanlon, Lorraine, Massahi, Sonny, Tomsick, John A., von Ballmoos, Peter, Wade, Colin   +7 more
core   +1 more source

Novel Laboratory Approaches in Heavy Chain Disease With Discordant Immunoglobulin Quantitation: A Case Report and Literature Review

Journal of Clinical Laboratory Analysis, EarlyView.
In this study, we investigated a rare case of γ‐heavy chain disease (γ‐HCD) through an integrated laboratory approach. Routine protein analyses (serum protein electrophoresis, immunotyping, and serum/urine immunofixation) identified an IgG monoclonal component without detectable light chains.
Eleonora Longhi, Artan Çeka, Fabiola Olivieri, Marco Moretti, Jacopo Sabbatinelli   +4 more
wiley   +1 more source

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source

Controlling Release Kinetics of an Adjuvant from a Depot Improves the Efficacy of Local Immunotherapy in Metastatic Cancer

Advanced Science
Biomaterials can improve cancer immunotherapies by controlling their release and thereby optimizing their time‐dependent engagement of the immune system.
Joshua J. Milligan, Rachel L. Strader, Arunangshu Chakrabarty, Max Ney, Parul Sirohi, Jonathan C. Su, Anastasia K. Varanko, Yulia Shmidov, Kalina Tsolova, Cassio Mendes Fontes, Anna Finkelstein, Rohinee Mattikalli, Yun‐Xing Wang, Lixin Fan, Xinghai Li, Smita K. Nair, Ashutosh Chilkoti   +16 more
doaj   +1 more source

Evaluation of Elastin-Like Polypeptides for Tumor Targeted Delivery of Doxorubicin to Glioblastoma

Molecules, 2019
To increase treatment efficiency for glioblastoma, we have developed a system to selectively deliver chemotherapeutic doxorubicin (Dox) to Glioblastoma (GBM) tumors.
Sonja Dragojevic, Rebecca Mackey, Drazen Raucher   +2 more
doaj   +1 more source