Results 81 to 90 of about 1,967 (171)

Asymmetric leaves2 and elongator, a histone acetyltransferase complex, mediate the establishment of polarity in leaves of Arabidopsis thaliana [PDF]

, 2011
Leaf primordia are generated around the shoot apical meristem. Mutation of the ASYMMETRIC LEAVES2 (AS2) gene of Arabidopsis thaliana results in defects in repression of the meristematic and indeterminate state, establishment of adaxial-abaxial polarity ...
Fleury, Delphine, Imai, Tomoya, Iwasaki, Mayumi, Kojima, Shoko, Machida, Chiyoko, Machida, Yasunori, Matsumura, Yoko, Takahashi, Hiro, Van Lijsebettens, Maria   +8 more
core   +3 more sources

Additional file 1 of Elp1 facilitates RAD51-mediated homologous recombination repair via translational regulation

, 2021
Additional file 1. Elp1 facilitates RAD51-mediated homologous recombination repair via translational regulation. Figure S1. Schematic of the Elp1 mutant allele. Figure S2. qRT-PCR analysis of the Elp1 mRNA expression by D3 MEFs. Figure S3. Knockout of Elp1 impaired cell cycle. Figure S4.
Chen, Wei-Ting, Tseng, Huan-Yi, Jiang, Chung-Lin, Lee, Chih-Ying, Chi, Peter, Chen, Liuh-Yow, Lo, Kai-Yin, Wang, I-Ching, Lin, Fu-Jung   +8 more
openaire   +1 more source

Pathway Analyses of Inherited Neuropathies Identify Putative Common Mechanisms of Axon Degeneration

Annals of Clinical and Translational Neurology, Volume 12, Issue 7, Page 1454-1464, July 2025.
ABSTRACT Objective Inherited neuropathies (IN) are associated with over 100 different genetic mutations presenting with a variety of phenotypes. This complexity suggests multiple pathways may converge onto a limited number of downstream pathways to effect axonal injury.
Christopher R. Cashman, Craig Blackstone, Reza Sadjadi   +2 more
wiley   +1 more source

Aspergillus fumigatus Elongator complex subunit 3 affects hyphal growth, adhesion and virulence through wobble uridine tRNA modification.

PLoS Pathogens, 2022
The eukaryotic multisubunit Elongator complex has been shown to perform multiple functions in transcriptional elongation, histone acetylation and tRNA modification.
Yuanwei Zhang, Yamei Wang, Jialu Fan, Guoxing Zhu, Ling Lu   +4 more
doaj   +1 more source

Performance Measurements of BLACS Routines on CRAY T3E [PDF]

, 2000
The ScaLAPACK library is based on the BLACS (Basic Linear Algebra Communication Subroutines) library. Unfortunately the optimized SHMEM-based CRAY T3E BLACS library contained in libcomm.a has a bug which leads to problems when sub-grids are created ...
Gutheil, Inge, Oechtering, Tobias
core  

Adolescents' and young adults' reactions to and perceived utility of carrier screening results in the context of a genomic research study

Journal of Genetic Counseling, Volume 34, Issue 3, June 2025.
Abstract Although guidelines have historically recommended deferring decisions about learning genomic information for conditions not actionable in childhood until adulthood, youth have increasing access to personal genomic information through research, clinical, and direct‐to‐consumer testing. However, little is known about young people's reactions to,
Haley N. Grimes, Michelle L. McGowan, Jessica A. Sinclair, Cynthia A. Prows, Ellen A. Lipstein, Melanie F. Myers   +5 more
wiley   +1 more source

Perspectives on the implications of carrying putative pathogenic variants in the medulloblastoma predisposition genes ELP1 and GPR161 [PDF]

, 2022
Miriam J. Smith, Emma R. Woodward, D. Gareth Evans   +2 more
openalex   +1 more source

External validation of and improvement upon a model for the prediction of placenta accreta spectrum severity using prospectively collected multicenter ultrasound data

Acta Obstetricia et Gynecologica Scandinavica, Volume 104, Issue S1, Page 20-28, April 2025.
This study evaluated the Sargent risk stratification algorithm for predicting placenta accreta spectrum (PAS) severity across multiple centers using the IS‐PAS database. The algorithm's ability to differentiate between abnormally adherent (FIGO grade 1) and invasive placenta (FIGO grades 2 and 3) was assessed, and a new model was developed based on ...
Magdalena Kolak, Stephen Gerry, Hubert Huras, Ammar Al Naimi, Karin A. Fox, Thorsten Braun, Vedran Stefanovic, Heleen van Beekhuizen, Olivier Morel, Alexander Paping, Charline Bertholdt, Pavel Calda, Zdenek Lastuvka, Andrzej Jaworowski, Egle Savukyne, Sally Collins, on behalf of IS‐PAS group, Kinga M. Chalubinski, Katarzyna Kawka‐Paciorkowska, Mina Mhallem Gziri, Maddalena Morlando, Frederic Chantraine, Gita Strindfors, Anja Bluth, Petra Hanulikova, Ozhan M. Turan, Andrew Rubenstein, Albaro Jose Nieto‐Calvache   +27 more
wiley   +1 more source

Familial Dysautonomia: Mechanisms and Models

Genetics and Molecular Biology
Hereditary Sensory and Autonomic Neuropathies (HSANs) compose a heterogeneous group of genetic disorders characterized by sensory and autonomic dysfunctions.
Paula Dietrich, Ioannis Dragatsis
doaj   +3 more sources

Loss of Elp3 Impairs the Acetylation and Distribution of Connexin-43 in the Developing Cerebral Cortex

Frontiers in Cellular Neuroscience, 2017
The Elongator complex is required for proper development of the cerebral cortex. Interfering with its activity in vivo delays the migration of postmitotic projection neurons, at least through a defective α-tubulin acetylation.
Sophie Laguesse, Sophie Laguesse, Laurent Nguyen, Laurent Nguyen, Pierre Close, Pierre Close, Laura Van Hees, Laura Van Hees, Alain Chariot, Alain Chariot, Alain Chariot, Brigitte Malgrange, Brigitte Malgrange   +12 more
doaj   +1 more source