Results 121 to 130 of about 684,507 (282)
First-Order Learning Models With the GDINA: Estimation With the EM Algorithm and Applications. [PDF]
Yigit HD, Douglas JA.
europepmc +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou +17 more
wiley +1 more source
EMeth: An EM algorithm for cell type decomposition based on DNA methylation data. [PDF]
Zhang H, Cai R, Dai J, Sun W.
europepmc +1 more source
In this paper, we firstly give a brief introduction of expectation maximization (EM) algorithm, and then discuss the initial value sensitivity of expectation maximization algorithm. Subsequently, we give a short proof of EM's convergence. Then, we implement experiments with the expectation maximization algorithm (We implement all the experiments on ...
openaire +2 more sources
Cryo‐EM analysis reveals an asymmetric MMOH–MMOB complex with distinct protomers, where MMOB binding triggers structural rearrangements from the surface to the active site. This conformational asymmetry shortens the Fe···Fe distance to 2.7 Å in one protomer, forming a geometry suitable for O2 activation and supporting a sequential catalytic mechanism ...
Yunha Hwang +9 more
wiley +1 more source
A Note on the Cowles-EM Algorithm for Bayesian Ordinal Probit Models
We describe a novel procedure for Bayesian cutpoint simulation in ordered probit models. Our approach capitalizes upon a series of auxiliary binary probit models implied by the ordinal probit to craft tailored proposal distributions for Metropolis ...
Justin L. Tobias
doaj +1 more source
EM algorithm for mixture of skew-normal distributions fitted to grouped data. [PDF]
Teimouri M.
europepmc +1 more source
In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN supplementation after high intensity muscle contractions enhances MuSC activation and differentiation, and accelerates muscle regeneration, providing new ...
Grith Højfeldt +14 more
wiley +1 more source
Prediction of earthquake hazard by hidden Markov model (around Bilecik, NW Turkey)
Can Ceren, Ergun Gul, Gokceoglu Candan
doaj +1 more source

