Results 71 to 80 of about 89,316 (267)

The Negative Binomial Distribution Efficiency in Finite Mixture of Semi-parametric Generalized Linear Models

پژوهش‌های ریاضی, 2019
Introduction Selection the appropriate statistical model for the response variable is one of the most important problem in the finite mixture of generalized linear models.
Farzad Eskandari
doaj  

Modeling Leukemia in Children Using Phase-type Distribution [PDF]

Journal of Kerman University of Medical Sciences, 2017
Background: In this study, with the aim of modeling Leukemia in children using Phase-type distribution, three transitional phases including diagnosis, brain metastasis and testis/ovary metastasis, and one absorotion phase of recovery/death have been ...
Marzieh Mahmoudimanesh, Abbas Bahrampour, Zahra Farahmandinia   +2 more
doaj  

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Estimation, Prediction and Life Testing Plan for the Exponentiated Gumbel Type-II Progressive Censored Data

Revstat Statistical Journal, 2023
This article accentuates the estimation and prediction of a three-parameter exponentiated Gumbel type-II (EGT-II) distribution when the data are progressively type-II (PT-II) censored.
Kousik Maiti, Suchandan Kayal
doaj  

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

An improved statistical model for taxonomic assignment of metagenomics

BMC Genetics, 2018
Background With the advances in the next-generation sequencing technologies, researchers can now rapidly examine the composition of samples from humans and their surroundings.
Yujing Yao, Zhezhen Jin, Joseph H Lee
doaj   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

A new iterative initialization of EM algorithm for Gaussian mixture models. [PDF]

PLoS One, 2023
You J, Li Z, Du J.
europepmc   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

The Information Bottleneck EM Algorithm

CoRR, 2012
Appears in Proceedings of the Nineteenth Conference on Uncertainty in Artificial Intelligence (UAI2003)
Gal Elidan, Nir Friedman
openaire   +3 more sources