Results 61 to 70 of about 89,316 (267)

E. coli Extracellular Matrix: A Tunable Composite With Hierarchical Structure

Advanced Materials, EarlyView.
The complex composite‐like mechanical behavior of E. coli biofilm matrix is the result of a synergic contribution of the rigid curli and swelling pEtN‐cellulose, and emerges from specific ratio and assembly conditions. The interactions between the two fibers govern biofilm hydration and characteristic wrinkling patterns, providing crucial insights for ...
Macarena Siri, Agustín Mangiarotti, Anne Seewald, Nikolai Rosenthal, Shahrouz Amini, Emeline Raguin, Peter Fratzl, Cécile M. Bidan   +7 more
wiley   +1 more source

An Integrated Approach for Making Inference on the Number of Clusters in a Mixture Model

Entropy, 2019
This paper presents an integrated approach for the estimation of the parameters of a mixture model in the context of data clustering. The method is designed to estimate the unknown number of clusters from observed data.
Erlandson Ferreira Saraiva, Adriano Kamimura Suzuki, Luis Aparecido Milan, Carlos Alberto de Bragança Pereira   +3 more
doaj   +1 more source

Tunable 3D‐Printed Static Mixers for Gradient Bioprinting With High Cell Viability

Advanced Materials Technologies, EarlyView.
ABSTRACT The fabrication of native tissue‐like structures with gradual transitions in material properties, cell types, and growth factors remains a major challenge in biofabrication due to the lack of suitable methods. Mimicking the hierarchical organization of living tissues is essential for functional models, yet creating gradient, multimaterial ...
Florian Hofmann, Jessica Faber, Franz Moser, Alessandro Cianciosi, Nicoletta Murenu, Joachim Schenk, Katrin G. Heinze, Natascha Schaefer, Silvia Budday, Tomasz Jungst   +9 more
wiley   +1 more source

Data‐Efficient Electromagnetic Surrogate Solver Through Dissipative Relaxation Transfer Learning

Advanced Optical Materials, EarlyView.
Dissipative relaxation transfer learning (DIRTL) enables data‐efficient training of electromagnetic surrogate solvers by pretraining data generated with artificial material loss before fine‐tuning on target lossless data. The framework suppresses resonant outlier effects during early training, allowing effective adaptation to high‐amplitude resonances ...
Sunghyun Nam, Chan Y. Park, Min Seok Jang   +2 more
wiley   +1 more source

Achieving the oracle property of OEM with nonconvex penalties

Statistical Theory and Related Fields, 2017
Thepenalised least square estimator of non-convex penalties such as the smoothly clipped absolute deviation (SCAD) and the minimax concave penalty (MCP) is highly nonlinear and has many local optima.
Shifeng Xiong, Bin Dai, Peter Z. G. Qian
doaj   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Maximum Likelihood Estimation for an SAG Mill Model Utilizing Physical Available Measurements

IEEE Access
In this paper, we have proposed a new paradigm for modeling of SAG mills. Typically, important parameters found in the modeling of such processes are described as state-space system model rather than unknown parameters.
Angel L. Cedeno, Maria Coronel, Rafael Orellana, Patricio Varas, Rodrigo Carvajal, Boris I. Godoy, Juan C. Aguero   +6 more
doaj   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Estimation of the Parameters of the Lomax Distribution using the EM Algorithm and Lindley Approximation

پژوهش‌های ریاضی, 2018
Estimation of statistical distribution parameter is one of the important subject of statistical inference. Due to the applications of Lomax distribution in business, economy, statistical science, queue theory, internet traffic modeling and so on, in this
Roshanak Zaman, Parviz Nasiri
doaj  

In Vivo Microplastic Detection With Photoacoustic Imaging

Advanced Science, EarlyView.
ABSTRACT Microplastics are posing an escalating threat to both ecological systems and human health. Yet, current methods for investigating their bioaccumulation are highly invasive, requiring destructive analysis of ex vivo tissues via mass spectrometry, dye labelling, or Raman microspectroscopy.
Joseph C. Bear, Olumide Ogunlade, Jayvian Mavi, Emily J. Deniszczyc, Daolong Chen, Heeva Javaheri, Paul Beard, Mark F. Lythgoe, Daniel J. Stuckey, P. Stephen Patrick   +9 more
wiley   +1 more source