Results 51 to 60 of about 18,144,236 (296)
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Surrogate modeling approximation using a mixture of experts based on EM joint estimation [PDF]
An automatic method to combine several local surrogate models is presented. This method is intended to build accurate and smooth approximation of discontinuous functions that are to be used in structural optimization problems.
Dimitri Bettebghor +9 more
core +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Manutenção de caminhos mínimos em grafos dinâmicos [PDF]
Orientadores : Prof. Dr. André Luiz Pires GuedesDissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Exatas, Programa de Pós-Graduação em Ciência da Computação. Defesa: Curitiba, 30/08/2011Inclui referênciasResumo: Esse trabalho faz
Martins, Geoffrey Alberto Vitorio
core +1 more source
To obtain reliable fish biomass estimates by acoustic methods, it is essential to filter out the signals from unwanted scatterers (e.g. zooplankton). When acoustic data are collected at more than one frequency, methods that exploit the differences in ...
López-Serrano Antonio +2 more
doaj +1 more source
Experimental Verification of PCH-EM Algorithm for Characterizing DSERN Image Sensors
The Photon Counting Histogram Expectation Maximization (PCH-EM) algorithm has recently been reported as a candidate method for the characterization of Deep Sub-Electron Read Noise (DSERN) image sensors.
Aaron J. Hendrickson +3 more
doaj +1 more source
During the service life of bridges, the bridge management systems (BMSs) seek to handle all performed assessment activities by controlling regular inspections, evaluations, and maintenance of these structures.
Adam Santos +5 more
semanticscholar +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
A fast algorithm for sparse probability density function construction [PDF]
A new sparse kernel density estimator is introduced. Our main contribution is to develop a recursive algorithm for the selection of significant kernels one at time using the minimum integrated square error (MISE) criterion for both kernel selection.
Hong, Xia, Chen, Sheng
core +2 more sources
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source

