Results 51 to 60 of about 18,144,236 (296)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Surrogate modeling approximation using a mixture of experts based on EM joint estimation [PDF]

open access: yes, 2010
An automatic method to combine several local surrogate models is presented. This method is intended to build accurate and smooth approximation of discontinuous functions that are to be used in structural optimization problems.
Dimitri Bettebghor   +9 more
core   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Manutenção de caminhos mínimos em grafos dinâmicos [PDF]

open access: yes, 2012
Orientadores : Prof. Dr. André Luiz Pires GuedesDissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Exatas, Programa de Pós-Graduação em Ciência da Computação. Defesa: Curitiba, 30/08/2011Inclui referênciasResumo: Esse trabalho faz
Martins, Geoffrey Alberto Vitorio
core   +1 more source

A probabilistic procedure for estimating an optimal echo-integration threshold using the Expectation-Maximisation algorithm★

open access: yesAquatic Living Resources, 2018
To obtain reliable fish biomass estimates by acoustic methods, it is essential to filter out the signals from unwanted scatterers (e.g. zooplankton). When acoustic data are collected at more than one frequency, methods that exploit the differences in ...
López-Serrano Antonio   +2 more
doaj   +1 more source

Experimental Verification of PCH-EM Algorithm for Characterizing DSERN Image Sensors

open access: yesIEEE Journal of the Electron Devices Society, 2023
The Photon Counting Histogram Expectation Maximization (PCH-EM) algorithm has recently been reported as a candidate method for the characterization of Deep Sub-Electron Read Noise (DSERN) image sensors.
Aaron J. Hendrickson   +3 more
doaj   +1 more source

Genetic‐based EM algorithm to improve the robustness of Gaussian mixture models for damage detection in bridges

open access: yes, 2017
During the service life of bridges, the bridge management systems (BMSs) seek to handle all performed assessment activities by controlling regular inspections, evaluations, and maintenance of these structures.
Adam Santos   +5 more
semanticscholar   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

A fast algorithm for sparse probability density function construction [PDF]

open access: yes, 2013
A new sparse kernel density estimator is introduced. Our main contribution is to develop a recursive algorithm for the selection of significant kernels one at time using the minimum integrated square error (MISE) criterion for both kernel selection.
Hong, Xia, Chen, Sheng
core   +2 more sources

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

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