Results 31 to 40 of about 89,307 (230)

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Promising or discouraging? Potentials and reactivity of real-time data collection in monitoring suicide-related thoughts and behaviors over weeks and months. Participants’ views on ecological momentary assessments and wearable use

Digital Health
Background Increasingly, studies and reviews have highlighted the potentials of ecological momentary assessments (EMAs) and wearables in suicide research.
Lena Spangenberg, Luise Böhler, Tina-Marie Hoke, Jana Serebriakova, Jannik Eimen, Thomas Forkmann, Maria Strauss, Katarina Stengler, Heide Glaesmer   +8 more
doaj   +1 more source

Histological and scanning electron microscopy investigation of the effects of titanium surface modifications on osseointegration in rabbits

Acta Orthopaedica et Traumatologica Turcica
Objective: This study aimed to compare the novel Estaş Medical Anodization (EMA) surface treatment technique with the techniques commonly used in the literature and to examine their effects on osteointegration in the rabbit tibia.
Burak Aydın, Zekeriya Öztemür, Neşe Yeldir, Seyran Kılınç, Sefa Aktı, İsmail Bilgin   +5 more
doaj   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Selecting an Ecological Momentary Assessment Platform: Tutorial for Researchers

Journal of Medical Internet Research
BackgroundAlthough ecological momentary assessment (EMA) has been applied in psychological research for decades, delivery methods have evolved with the proliferation of digital technology.
Lauren M Henry, Eleanor Hansen, Justin Chimoff, Kimberly Pokstis, Miryam Kiderman, Reut Naim, Joe Kossowsky, Meghan E Byrne, Silvia Lopez-Guzman, Katharina Kircanski, Daniel S Pine, Melissa A Brotman   +11 more
doaj   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Short‐term response to biologic therapy in psoriatic arthritis (PsA) is not influenced by disease duration at initiation of therapy

Arthritis Care &Research, Accepted Article.
Objectives We aimed to determine whether the short‐term response to biologics in biologic‐naïve psoriatic arthritis (PsA) is better in patients initiating biologic treatment early in the disease course. Methods PsA patients who started biologic therapy from the year 2000 to 2025 were included for analysis. Patients considered in the early treatment (ET)
Sung Min Cho, Shangyi Gao, Daniel Pereira, Richard J. Cook, Dafna D. Gladman   +4 more
wiley   +1 more source

Reliability and Validity of Noncognitive Ecological Momentary Assessment Survey Response Times as an Indicator of Cognitive Processing Speed in People’s Natural Environment: Intensive Longitudinal Study

JMIR mHealth and uHealth, 2023
BackgroundVarious populations with chronic conditions are at risk for decreased cognitive performance, making assessment of their cognition important.
Raymond Hernandez, Claire Hoogendoorn, Jeffrey S Gonzalez, Haomiao Jin, Elizabeth A Pyatak, Donna Spruijt-Metz, Doerte U Junghaenel, Pey-Jiuan Lee, Stefan Schneider   +8 more
doaj   +1 more source

Non‐Monotonic Changes in the Thermal Conductivity of Conjugated Polymer Films with Increasing Levels of Chemical Doping

Advanced Functional Materials, EarlyView.
Thermal conductivity changes non‐monotonically as regioregular (RR) and regiorandom (RRa) P3HT films are doped with F4TCNQ as a function of the extent to which P3HT is doped: an increase in thermal conductivity is observed upon lightly doping P3HT compared to the undoped film, followed by a decrease in the heavily doped regime. ABSTRACT The performance
Reid W. Wilson, Xinping Shi, Diego Garcia Vidales, Abigail Slimp, Zerina Mehmedović, Alexander F. Simafranca, Eric C. Wu, Sarah H. Tolbert, Richard B. Wilson, Benjamin J. Schwartz   +9 more
wiley   +1 more source