Results 41 to 50 of about 89,307 (230)

Doença celíaca em crianças e adolescentes com síndrome de Down Celiac disease in children and adolescents with Down syndrome

Jornal de Pediatria, 2005
OBJETIVOS: Alta prevalência de doença celíaca em pacientes com síndrome de Down tem sido descrita em vários países. No entanto, no Brasil ainda não há relatos mostrando essa associação. O presente estudo teve como objetivo avaliar a prevalência de doença
Renato M. Nisihara, Lorete M. S. Kotze, Shirley R. R. Utiyama, Nanci P. Oliveira, Patrícia T. Fiedler, Iara T. Messias-Reason   +5 more
doaj   +1 more source

Programmable 2D Magnetic Clusterphenes With High Curie Temperature and Strong Magnetic Anisotropy via Cluster Assembly and Ligand Synergy

Advanced Functional Materials, EarlyView.
Programmable 2D magnetic clusterphenes are realized through a ligand‐mediated cluster‐assembly strategy. Direct linking of magnetic superatomic clusters enhances electron delocalization and symmetry breaking, enabling the concurrent strengthening of magnetic exchange interactions and spin–orbit coupling.
Junxiang Fu, Zhuohang Fang, Haidi Wang, Ye Yang, Weiduo Zhu, Weiwei Chen, Yu Zhang, Haixiao Xiao, Zhao Chen, Hongyan Lv, Xiaofeng Liu, Xiangyang Li, Xiao Cheng Zeng, Zhongjun Li   +13 more
wiley   +1 more source

Spin Dynamics in the van der Waals Ferromagnet CrTe2 Engineered by Niobium Doping

Advanced Functional Materials, EarlyView.
Spin‐dynamic magnetic properties of van der Waals (vdW) ferromagnet 1T‐CrTe2 are tuned via niobium (Nb) as Cr1‐xNbxTe2 (x = 0–0.2). Nb doping enables wide‐band tuning of the resonance frequency from 40 GHz down to the few‐GHz regime, accompanied by a moderate increase in the Gilbert damping from ∼0.066 to ∼0.14.
Dhan Raj Lawati, Prem Bahadur Karki, Jitender Kumar, Karishma Prasad, Mohamed A. Elekhtiar, Kai Huang, Bibek Tiwari, Suvechhya Lamichhane, Rupak Timalsina, Zane Hubble, Ayodimeji E. Aregbesola, John Watt, Sy‐Hwang Liou, Evgeny Y. Tsymbal, Jian Wang, Kapildeb Ambal, Abdelghani Laraoui   +16 more
wiley   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

Advanced Materials, EarlyView.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot, Sebastian Jung, Sébastien Harlepp, Alexandre Detappe   +3 more
wiley   +1 more source

Brain and muscle redox imbalance elicited by acute ethylmalonic acid administration.

PLoS ONE, 2015
Ethylmalonic acid (EMA) accumulates in tissues and biological fluids of patients affected by short-chain acyl-CoA dehydrogenase deficiency (SCADD) and ethylmalonic encephalopathy, illnesses characterized by neurological and muscular symptoms. Considering
Patrícia Fernanda Schuck, Ana Paula Milanez, Francine Felisberto, Leticia Selinger Galant, Jéssica Luca Machado, Camila Brulezi Furlanetto, Fabricia Petronilho, Felipe Dal-Pizzol, Emilio Luiz Streck, Gustavo Costa Ferreira   +9 more
doaj   +1 more source

ChicGrasp: Imitation‐Learning‐Based Customized Dual‐Jaw Gripper Control for Manipulation of Delicate, Irregular Bio‐Products

Advanced Robotics Research, EarlyView.
Automated poultry processing lines still rely on humans to lift slippery, easily bruised carcasses onto a shackle conveyor. Deformability, anatomical variance, and hygiene rules make conventional suction and scripted motions unreliable. We present ChicGrasp, an end‐to‐end hardware‐software co‐designed imitation learning framework, to offer a ...
Amirreza Davar, Zhengtong Xu, Siavash Mahmoudi, Pouya Sohrabipour, Chaitanya Pallerla, Yu She, Wan Shou, Philip Glen Crandall, Dongyi Wang   +8 more
wiley   +1 more source

Ecological Momentary Assessment to Measure Social Connectedness in Older Adults: Integrative Review

Journal of Medical Internet Research
BackgroundThe importance of social connectedness as a determinant of health and well-being in older adults is well-established. Ecological momentary assessment (EMA) shows promise for real-time measurement of social interactions ...
Seongmi Choi, Hun Kang, Jiyoung Shin, Sang Hui Chu, JiYeon Choi   +4 more
doaj   +1 more source

To what degree are review outcomes aligned for new active substances (NASs) between the European Medicines Agency and the US Food and Drug Administration? A comparison based on publicly available information for NASs initially approved in the time period 2014 to 2016

BMJ Open, 2019
Objective To compare review outcome alignment between European Medicines Agency (EMA) and US Food and Drug Administration (FDA) for medicines approved by both agencies in the time period 2014–2016.Design Using publicly available information from FDA and ...
Thomas Christian Kühler, Magda Bujar, Neil McAuslane, Lawrence Liberti   +3 more
doaj   +1 more source

Evaluation of the hypothalamo-pituitary-adrenal axis using the cortisol awakening response test in patients with type 1 diabetes mellitus with and without depression: Multicenter Argentine Study (EMA-1)

Revista de la Sociedad Argentina de Diabetes, 2020
Introduction: depression (DP) has a high prevalence in patients with type 1 diabetes mellitus (DM1) and is associated with negative clinicals consequences like more cardiovascular morbimortality and chronic complications. There are few studies published about the dysregulation of hypothalamo-pituitary-adrenal axis (H-P-A) in DM1 with DP and the ...
Adriana Álvarez, Andrea Kozak, Lucas Costa, Guillermo Alzueta, Juan Bauchi, Claudia De Boni, Guillermo Dieuzeide, Olga Escobar, Teresita García, Patricia Mascaró, Olguita Vera, Diego González, Bibiana Fabre, Luis Grosembacher   +13 more
openaire   +1 more source