Results 71 to 80 of about 27,445 (234)

Minor contribution of mutations at iniA codon 501 and embC-embA intergenic region in ethambutol-resistant clinical Mycobacterium tuberculosis isolates in Kuwait

Annals of Clinical Microbiology and Antimicrobials, 2009
Background Ethambutol (EMB) is a first-line drug for the treatment of tuberculosis (TB). Resistance to EMB in Mycobacterium tuberculosis isolates is mediated by mutations in several genes involved in arabinan synthesis notably three emb (arabinosyl ...
Ahmad Suhail, Jaber Al-Anoud, Mokaddas Eiman   +2 more
doaj   +1 more source

Right Coronary Artery to Coronary Sinus Fistula Post Endomyocardial Biopsy: A Case Report of a Rare Complication

Case Reports in Cardiology, 2020
Endomyocardial biopsy (EMB) continues to remain the gold standard for surveillance of rejection post orthotropic heart transplantation (OHT). It can be performed under fluoroscopic or echocardiographic guidance.
Aniket S. Rali, Farhad Sami, Andrew Sauer, Zubair Shah   +3 more
doaj   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

Residency and Space Use of Endangered Smoothhound Sharks (Mustelus mustelus) in Relation to Marine Protection and Demersal Longline Fishing Along South Africa's South Coast

Fisheries Management and Ecology, EarlyView.
ABSTRACT Shark populations are declining globally and the effectiveness of marine protected areas (MPAs) as a conservation tool may vary by species and environmental context. This study assessed space use and residency of smoothhound sharks (Mustelus mustelus)—an endangered, yet highly exploited shark—in relation to spatial protection and fishing risk ...
Eugin Bornman, Taryn S. Murray, Neil Hammerschlag, Enrico Gennari   +3 more
wiley   +1 more source

Synthesis and Antimycobacterial Assays of Some New Ethambutol Analogs

Molecules
Ethambutol (EMB) is a first-line anti-tuberculosis drug that is also considered in treatment regimens for infections caused by non-tuberculous mycobacteria (NTM).
Rana Abdelaziz, Mthandazo Dube, Lea Mann, Adrian Richter, Dina Robaa, Norbert Reiling, Mohammad Abdel-Halim, Peter Imming   +7 more
doaj   +1 more source

Peculiarities of perceiving aging by men and women during the middle and late adulthood periods [PDF]

Известия Саратовского университета. Новая серия: Акмеология образования. Психология развития
The relevance of the study is determined by the necessity for scientifi c substantiation and development of methods aimed at improving the quality of life in the old age.
Krupina, Kristina M., Petrash, Marina D., Golubitskaya, Daria I., Strizhitskaya, Olga Yu.   +3 more
doaj   +1 more source

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

Journal of Integrative Plant Biology, EarlyView.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba, Cécile Bres, Aurora Alaguero‐Cordovilla, Riyazuddin Riyazuddin, Qingyi Wang, Johann Petit, Jean‐Philippe Mauxion, Lara Caballero, David Latrasse, Bénédicte Bakan, Rim Brik‐Chaouche, David Esteve‐Bruna, Moussa Benhamed, Christophe Rothan, José Manuel Pérez‐Pérez   +14 more
wiley   +1 more source

Developing a coaching manual to provide human support for the Mothers and Babies Online (eMB) perinatal mental health intervention

Internet Interventions
Background: Depression that occurs in pregnancy or postpartum (perinatal depression) impacts 1 in 5 mothers, yet access to effective and high-quality preventative interventions remains elusive for most.
Lara Baez, Jaime Hamil, Elaine McBride, Katherine A. Czech, Bayley J. Taple, Adriana Santillano, Mingjing Huang, Alinne Z. Barrera, S. Darius Tandon   +8 more
doaj   +1 more source

SynapTrack: An automated tool for synapse quantification

Journal of Microscopy, EarlyView.
Abstract Reliable synapse quantification remains challenging, particularly in high‐throughput fluorescence imaging workflows. Here we present SynapTrack, a fully automated FIJI/ImageJ‐based tool for quantifying synapses in cultured neurons and brain tissue sections with minimal user intervention.
Carlos Gallego‐García, Elena Martínez‐Blanco, F. Javier Díez‐Guerra   +2 more
wiley   +1 more source

EMB-driven glioblastoma multiforme progression via the MCT4/GPX3 axis: therapeutic inhibition by Ganxintriol A

Journal of Translational Medicine
Background Embigin (EMB) is a transmembrane glycoprotein highly expressed in glioblastoma multiforme (GBM), yet its role in GBM progression remains unclear.
Bo Cheng, Jing Liu, Ling Gao, Ziwen Zhu, Yang Yang, Shangqi Liu, Xiaojin Wu   +6 more
doaj   +1 more source