Results 1 to 10 of about 25,093 (162)

Neuro-ophthalmic complications of tuberculosis and its treatment: a systematic review and meta-analysis [PDF]

Frontiers in Ophthalmology
IntroductionTuberculosis (TB) and its treatment have been associated with significant neuro-ophthalmic morbidity; however, the magnitude and determinants of these complications remain incompletely characterized.
Ahmed A. Alessa, Ahmed Zuhier Awan, Abdulkarim B. Almutairi, Ibrahim Ghassan Ajabnoor, Mohammed Marouf M. Jan, Ahmed Y. Azzam, Ahmed Y. Azzam, Nooran Badeeb, Nooran Badeeb   +8 more
doaj   +2 more sources

Novel Anti-Tuberculosis Nanodelivery Formulation of Ethambutol with Graphene Oxide

Molecules, 2017
Tuberculosis (TB) is a bacterial disease responsible for millions of infections and preventable deaths each year. Its treatment is complicated by patients’ noncompliance due to dosing frequency, lengthy treatment, and adverse side effects associated with
Sharida Fakurazi, Bullo Saifullah, Mohd Zobir Hussein   +2 more
exaly   +3 more sources

Incidence and prognostic factor of ethambutol‐related optic neuropathy: 10‐year experience in southern Taiwan

Kaohsiung Journal of Medical Sciences, 2015
To investigate the incidence and prognostic factors of ethambutol-related optic neuropathy (EON) in one medical center of southern Taiwan, a retrospective chart review study with 4803 newly diagnosed tuberculosis cases from January 2002 to July 2011 at ...
Shwu-Jiuan Sheu
exaly   +3 more sources

Knowledge, Attitudes, and Practices Toward Drug-Induced Visual Impairment Due to Antitubercular Therapy Among Medical Officers of Primary Health Care Centers in Karnataka, South India [PDF]

Clinical Ophthalmology
Shreya Bera,1 Teena Mariet Mendonca,1 Rajesh Nayak,1 Sowmya PD,2 Sri Archana,1 Avinash Suresh,1 Gladys Rodrigues,1 Ajay Kamath1 1Department of Ophthalmology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India ...
Bera S, Mendonca TM, Nayak R, PD S, Archana S, Suresh A, Rodrigues G, Kamath A   +7 more
doaj   +2 more sources

Mutations in the ubiA gene are the major mechanism of ethambutol resistance in Mycobacterium avium [PDF]

Microbiology Spectrum
Mycobacterium avium-intracellulare complex (MAC) infections are the most common nontuberculous mycobacterial infections, and ethambutol (EMB) is one of the main therapeutic agents used to treat MAC infections.
Yuwei Qiu, Xu Dong, Dan Cao, Xiuzhi Jiang, Zhongkang Ji, Pusheng Xu, Yi Li, Kaijing Xu, Ying Zhang   +8 more
doaj   +2 more sources

Ethambutol optic neuropathy

Frontiers in Neurology
Ethambutol is an antitubercular drug that is commonly used in the areas of the world that is endemic to tuberculosis. It is used in infections caused by Mycobacterium tuberculosis and some non-tuberculous infections caused by Mycobacterium species ...
Padmaja Sudhakar, Kishor Acharya, Tonse Ashwini Kini   +2 more
exaly   +3 more sources

Risk Factors of Optic Neuropathy in Ethambutol Users: Interaction with Isoniazid and Other Associated Conditions of Toxic Optic Neuropathy

Toxics
(1) Background: To investigate the risk factors associated with optic neuropathy (ON) and validate the hypothesis that concomitant isoniazid use and other causes of toxic ON affect the development of ON in ethambutol users. (2) Methods: This cohort study
Seong Joon Ahn, Jiyeong Kim, Kim Jiyeong   +2 more
exaly   +3 more sources

Adverse Drug Reactions to a Daily Fixed-dose Combination Based Antituberculosis Treatment Regime in India’s National Tuberculosis Elimination Programme: A Prospective Cohort Study [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: In India, the daily weight-based, Fixed Dose Combination (FDC) Antituberculosis Treatment (ATT) regime under the National Tuberculosis Elimination Programme (NTEP) was introduced, replacing the previous intermittent regime with the ...
Kapil Mate, Gyanshankar Mishra, Radha Munje   +2 more
doaj   +1 more source

Ethambutol toxicity: Expert panel consensus for the primary prevention, diagnosis and management of ethambutol-induced optic neuropathy

Indian Journal of Ophthalmology, 2021
Ethambutol use may lead to permanent vision loss by inducing a dose- and duration-dependent optic neuropathy. This has been of concern to ophthalmologists and physicians both; however, ethambutol continues to be used because of its anti-mycobacterial ...
Rohit Saxena, Digvijay Singh, Swati Phuljhele, V Kalaiselvan, Satya Karna, Rashmin Gandhi, Anupam Prakash, Rakesh Lodha, Anant Mohan, Vimla Menon, Rajeev Garg   +10 more
doaj   +1 more source

The first-line antituberculosis drugs, and their fixed-dose combination induced abnormal sperm morphology and histological lesions in the testicular cells of male mice

Frontiers in Cell and Developmental Biology, 2022
Rifampicin (RIF), Isoniazid (INH), Ethambutol (EMB), Pyrazinamide (PZA), and/or their fixed-dose combination (FDC) are extensively prescribed in the cure of Tuberculosis (TB) globally.
Adekunle A. Bakare, Victoria Y. Moses, Charles T. Beckely, Toluwani I. Oluyemi, Gift O. Ogunfeitimi, Aduragbemi A. Adelaja, Glory T. Ayorinde, Adeyinka M. Gbadebo, Olukunle S. Fagbenro, Olusegun I. Ogunsuyi, Opeoluwa M. Ogunsuyi, Olusoji Mayowa Ige   +11 more
doaj   +1 more source