Results 21 to 30 of about 25,915 (168)
Genetic polymorphism related to ethambutol outcomes and susceptibility to toxicity
Frontiers in Genetics, 2023 The World Health Organization (WHO) stated that ensuring access to effective and optimal treatment is a key component to eradicate tuberculosis (TB) through the End TB Strategy.
Melisa Intan Barliana +4 more
doaj +1 more source
Ethambutol-induced bullous skin lesions in mycobacterium kansasii lung infection
International Journal of Mycobacteriology, 2022 Mycobacterium kansasii is the second most common cause of nontuberculous mycobacterial (NTM) lung disease after Mycobacterium avium complex infection in the United States.[1] The first-line therapy for M.
Venkateswara K Kollipara +3 more
doaj +1 more source
Ethambutol-induced optic neuritis in a case of pulmonary tuberculosis
TNOA Journal of Ophthalmic Science and Research, 2022 Ethambutol hydrochloride (EMB) is one of the integral first-line antitubercular agents used in both intensive and continuation phase as per Revised National Tuberculosis Control Programme guidelines.
Shatavisa Mukherjee +3 more
doaj +1 more source
Role of ethambutol and rifampicin in the treatment of Mycobacterium avium complex pulmonary disease
BMC Pulmonary Medicine, 2019 Background A three-drug regimen (macrolide, ethambutol, and rifampicin) is recommended for the treatment of Mycobacterium avium complex pulmonary disease (MAC-PD).
Hyung-Jun Kim +6 more
doaj +1 more source
Медицинская иммунология, 2014 . The article deals with results of studying combined effects of ethambutol and protein antigen of Мycobacterium tuberculosis upon proliferative response and cytokine-producing ability of peripheral blood mononuclear cells in patients with infiltrative ...
V. A. Serebryakova +8 more
doaj +1 more source
Biomedicine & Pharmacotherapy, 1990 Ethambutol gained rapid acceptance as a substitute for PAS in tuberculosis therapy because of improved patient tolerance and convenience of administration. Ocular toxicity was recognized early on but was thought to be a problem only at higher dosages.
openaire +2 more sources
Mitochondrial Mutations in Ethambutol-Induced Optic Neuropathy
Frontiers in Cell and Developmental Biology, 2021 Background: Ethambutol-induced optic neuropathy (EON) is a well-recognized ocular complication in patients who take ethambutol as a tuberculosis treatment. The aim of the current study was to investigate the presence of mitochondrial mutations, including
Xiao-Hui Zhang +8 more
doaj +1 more source
Microbiology Spectrum, 2022 The emergence of antimicrobial resistance warrants for the development of improved treatment approaches. In this regard, peptide nucleic acids (PNAs) have shown great promise, exhibiting antibiotic properties through the targeting of cellular nucleic ...
Karishma Berta Cotta +2 more
doaj +1 more source
Drug rash with eosinophilia and systemic symptoms syndrome due to anti-TB medication
Journal of Family Medicine and Primary Care, 2013 Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a severe, idiosyncratic, multi-system reaction characterized by the clinical triad of fever, rash, and internal organ involvement.
Dharmesh H Kaswala
doaj +1 more source
Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies
Medicinal Research Reviews, EarlyView.ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva +23 more
wiley +1 more source