Results 11 to 20 of about 25,028 (165)

Effect of Increased Inoculum Size on Drug Susceptibility of Mycobacterium tuberculosis: Challenges in Reliable Drug Resistance Detection. [PDF]

open access: yesMicrobiologyopen
Impact of increased inoculum size on drug susceptibility testing of Mycobacterium tuberculosis and its role in the detection of drug resistance ABSTRACT Inoculum preparation of Mycobacterium tuberculosis isolates is a critical step for the reproducibility of drug susceptibility tests (DST) and the prevention of false results.
Yildirim K   +5 more
europepmc   +2 more sources

Evaluation of the Long-term Effect of Ethambutol Usage on the Retinal Nerve Fiber Layer Using Spectral-Domain Optical Coherence Tomography

open access: yesBeyoglu Eye Journal, 2020
INTRODUCTION[|]The aim of this study was to use spectral-domain optical coherence tomography (SD-OCT) to evaluate the long-term effect of ethambutol on the optic nerve fiber layer.[¤]METHODS[|]Twenty eyes of 10 patients who had been treated with ...
Gul Varan, Leyla Hazar, Ahmet Sahin
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Mitochondrial Mutations in Ethambutol-Induced Optic Neuropathy

open access: yesFrontiers in Cell and Developmental Biology, 2021
Background: Ethambutol-induced optic neuropathy (EON) is a well-recognized ocular complication in patients who take ethambutol as a tuberculosis treatment. The aim of the current study was to investigate the presence of mitochondrial mutations, including
Xiao-Hui Zhang   +8 more
doaj   +1 more source

Mycobacterial Cell Wall Synthesis Inhibitors Cause Lethal ATP Burst

open access: yesFrontiers in Microbiology, 2018
Mycobacterial cell wall inhibitors interfere with targets involved in synthesis of mycolic acids, arabinogalactan and peptidoglycan. These antibiotics corrupt structural integrity of the cell envelope and this is believed to be the cause of drug mediated
Annanya Shetty, Thomas Dick, Thomas Dick
doaj   +1 more source

Potentiating the Anti-Tuberculosis Efficacy of Peptide Nucleic Acids through Combinations with Permeabilizing Drugs

open access: yesMicrobiology Spectrum, 2022
The emergence of antimicrobial resistance warrants for the development of improved treatment approaches. In this regard, peptide nucleic acids (PNAs) have shown great promise, exhibiting antibiotic properties through the targeting of cellular nucleic ...
Karishma Berta Cotta   +2 more
doaj   +1 more source

Molecular resistance of Ethambutol in clinical samples obtained from patients admitted to the health center in Ardabil province using MAS-PCR [PDF]

open access: yesمجله پزشکی دانشگاه علوم پزشکی تبریز
Background. Global stop TB is a critical strategy which aims at reducing the incidence of tuberculosis to less than one case per one million people by 2050.
Furugh Babazadeh   +5 more
doaj   +1 more source

The Effect of Ethambutol on Optic Nerve by Spectral Domain Optical Coherence Tomography

open access: yesNamık Kemal Tıp Dergisi, 2020
Aim:To evaluate; the retinal nerve fiber layer difference between healthy control groups and patients who were taking ethambutol medication by using spectral domain optical coherence tomography (SD-OCT) and to evaluate the usage of SD-OCT for early ...
Gül VARAN, Ahmet ŞAHİN
doaj   +1 more source

Prevalence and Molecular Characteristics Based on Whole Genome Sequencing of Mycobacterium tuberculosis Resistant to Four Anti-Tuberculosis Drugs from Southern Xinjiang, China

open access: yesInfection and Drug Resistance, 2021
Aiketaguli Anwaierjiang,1,* Quan Wang,2,* Haican Liu,3,* Chunjie Yin,1 Miao Xu,2 Machao Li,3 Mengwen Liu,1 Yan Liu,2 Xiuqin Zhao,3 Jinbao Liu,1 Guilian Li,3 Xiaokaiti Mijiti,2 Kanglin Wan3 1College of Public Health, Xinjiang Medical ...
Anwaierjiang A   +12 more
doaj  

Novel Anti-Tuberculosis Nanodelivery Formulation of Ethambutol with Graphene Oxide

open access: yesMolecules, 2017
Tuberculosis (TB) is a bacterial disease responsible for millions of infections and preventable deaths each year. Its treatment is complicated by patients’ noncompliance due to dosing frequency, lengthy treatment, and adverse side effects associated with
Bullo Saifullah   +6 more
doaj   +1 more source

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