Results 11 to 20 of about 25,915 (168)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Correlations among the plasma concentrations of first-line anti-tuberculosis drugs and the physiological parameters influencing concentrations

Frontiers in Pharmacology, 2023
Background: The plasma concentrations of the four most commonly used first-line anti-tuberculosis (TB) drugs, isoniazid (INH), rifampicin (RMP), ethambutol (EMB), and pyrazinamide (PZA), are often not within the therapeutic range.
Lin Cheng, Ming Luo, Yan Guo, Yunfan Fan, Pengsen Wang, Gang Zhou, Shiwei Qin, Bangbi Weng, Peibo Li, Zhirui Liu, Songtao Liu   +10 more
doaj   +1 more source

Is Dosing of Ethambutol as Part of a Fixed-Dose Combination Product Optimal for Mechanically Ventilated ICU Patients with Tuberculosis? A Population Pharmacokinetic Study

Antibiotics, 2021
Background: Tuberculosis (TB) patients admitted to intensive care units (ICU) have high mortality rates. It is uncertain whether the pharmacokinetics of first-line TB drugs in ICU patients are different from outpatients.
Francisco Beraldi-Magalhaes, Suzanne L. Parker, Cristina Sanches, Leandro Sousa Garcia, Brenda Karoline Souza Carvalho, Mariana Millan Fachi, Marcus Vinicius de Liz, Roberto Pontarolo, Jeffrey Lipman, Marcelo Cordeiro-Santos, Jason A. Roberts   +10 more
doaj   +1 more source

Mycobacterial Cell Wall Synthesis Inhibitors Cause Lethal ATP Burst

Frontiers in Microbiology, 2018
Mycobacterial cell wall inhibitors interfere with targets involved in synthesis of mycolic acids, arabinogalactan and peptidoglycan. These antibiotics corrupt structural integrity of the cell envelope and this is believed to be the cause of drug mediated
Annanya Shetty, Thomas Dick, Thomas Dick
doaj   +1 more source

Ethambutol-associated mania: A rare case report

Journal of Medical Sciences, 2021
Ethambutol is the primary commonly used antitubercular drug for the treatment of tuberculosis and atypical mycobacterial infection. Central nervous system toxicity other than optic neuropathy is not widely reported.
Shabir Ahmad Dar, Aaliya Khanam, Naveed Nazir Shah   +2 more
doaj   +1 more source

Molecular resistance of Ethambutol in clinical samples obtained from patients admitted to the health center in Ardabil province using MAS-PCR [PDF]

مجله پزشکی دانشگاه علوم پزشکی تبریز
Background. Global stop TB is a critical strategy which aims at reducing the incidence of tuberculosis to less than one case per one million people by 2050.
Furugh Babazadeh, Jafar Mohammadshahi, Hafez Mirzanejad-Asl, Reyhaneh Rahimzadeh, Zohreh Neyestani, Roghayeh Teimourpour   +5 more
doaj   +1 more source

The Effect of Ethambutol on Optic Nerve by Spectral Domain Optical Coherence Tomography

Namık Kemal Tıp Dergisi, 2020
Aim:To evaluate; the retinal nerve fiber layer difference between healthy control groups and patients who were taking ethambutol medication by using spectral domain optical coherence tomography (SD-OCT) and to evaluate the usage of SD-OCT for early ...
Gül VARAN, Ahmet ŞAHİN
doaj   +1 more source

Prevalence and Molecular Characteristics Based on Whole Genome Sequencing of Mycobacterium tuberculosis Resistant to Four Anti-Tuberculosis Drugs from Southern Xinjiang, China

Infection and Drug Resistance, 2021
Aiketaguli Anwaierjiang,1,* Quan Wang,2,* Haican Liu,3,* Chunjie Yin,1 Miao Xu,2 Machao Li,3 Mengwen Liu,1 Yan Liu,2 Xiuqin Zhao,3 Jinbao Liu,1 Guilian Li,3 Xiaokaiti Mijiti,2 Kanglin Wan3 1College of Public Health, Xinjiang Medical ...
Anwaierjiang A, Wang Q, Liu H, Yin C, Xu M, Li M, Liu M, Liu Y, Zhao X, Liu J, Li G, Mijiti X, Wan K   +12 more
doaj  

Novel Anti-Tuberculosis Nanodelivery Formulation of Ethambutol with Graphene Oxide

Molecules, 2017
Tuberculosis (TB) is a bacterial disease responsible for millions of infections and preventable deaths each year. Its treatment is complicated by patients’ noncompliance due to dosing frequency, lengthy treatment, and adverse side effects associated with
Bullo Saifullah, Alina Chrzastek, Arundhati Maitra, Bullo Naeemullah, Sharida Fakurazi, Sanjib Bhakta, Mohd Zobir Hussein   +6 more
doaj   +1 more source

Mutations and insights into the molecular mechanisms of resistance of Mycobacterium tuberculosis to first-line [PDF]

Genetics and Molecular Biology, 2023
Genetically antimicrobial resistance in Mycobacterium tuberculosis is currently one of the most important aspects of tuberculosis, considering that there are emerging resistant strains for almost every known drug used for its treatment.
Nicolas de Oliveira Rossini, Marcio Vinicius Bertacine Dias   +1 more
doaj   +1 more source