Results 71 to 80 of about 1,397,905 (314)

Embedded monopoles

open access: yesPhysics Letters B, 2002
Using the embedded defect method, we classify the possible embeddings of a 't Hooft-Polyakov monopole in a general gauge theory. We then discuss some similarities with embedded vortices and relate our results to fundamental monopoles.
openaire   +3 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Modal Adverbs in FDG: Putting the Theory to the Test

open access: yesOpen Linguistics, 2018
One of the distinctive features of the theory of Functional Discourse Grammar (FDG) is that it distinguishes various hierarchically organized layers of analysis, each of which is provided with a slot for modifiers relevant at the layer in question ...
Keizer Evelien
doaj   +1 more source

Extended Factorization Machines for Sequential Recommendation

open access: yesIEEE Access, 2020
Users' historical activities are usually contained in real-life sequential recommendation systems to predict their future behaviors. In this situation, traditional Factorization Machines (FMs) approaches may be not suitable.
Nuan Wen, Fang Zhang
doaj   +1 more source

Can Density Matrix Embedding Theory with the Complete Activate Space Self-Consistent Field Solver Describe Single and Double Bond Breaking in Molecular Systems?

open access: yes, 2017
Density matrix embedding theory (DMET) [Phys. Rev. Lett.2012, 109, 186404] has been demonstrated as an efficient wave-function-based embedding method to treat extended systems.
Bernales, Varinia   +2 more
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Semantic search using protein large language models detects class II microcins in bacterial genomes

open access: yesmSystems
Class II microcins are antimicrobial peptides that have shown some potential as novel antibiotics. However, to date, only 10 class II microcins have been described, and the discovery of novel microcins has been hampered by their short length and high ...
Anastasiya V. Kulikova   +3 more
doaj   +1 more source

VINEA: a policy-based virtual network embedding architecture [PDF]

open access: yes, 2013
Network virtualization has enabled new business models by allowing infrastructure providers to lease or share their physical network. To concurrently run multiple customized virtual network services, such infrastructure providers need to run a virtual ...
Esposito, Flavio   +2 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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