Results 81 to 90 of about 64,000 (305)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Embedding with Vaidya geometry
European Physical Journal C: Particles and Fields, 2020 The Vaidya metric is important in describing the exterior spacetime of a radiating star and for describing astrophysical processes. In this paper we study embedding properties of the generalized Vaidya metric.
A. V. Nikolaev, S. D. Maharaj
doaj +1 more source
Homeomorphic Embedding for Online Termination of Symbolic Methods
, 2002 Well-quasi orders in general, and homeomorphic embedding in particular, have gained popularity to ensure the termination of techniques for program analysis, specialisation, transformation, and verification. In this paper we survey and discuss this use of
Michael Leuschel, Leuschel, Michael
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2023 We investigate the negatively charged nitrogen-vacancy center in diamond using periodic density matrix embedding theory (pDMET). To describe the strongly correlated excited states of this system, the complete active space self-consistent field (CASSCF ...
Soumi, Haldar +3 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Lp Smoothness on Weighted Besov–Triebel–Lizorkin Spaces in terms of Sharp Maximal Functions
Journal of Mathematics, 2021 It is known, in harmonic analysis theory, that maximal operators measure local smoothness of Lp functions. These operators are used to study many important problems of function theory such as the embedding theorems of Sobolev type and description of ...
Ferit Gürbüz, Ahmed Loulit
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Electronic Proceedings in Theoretical Computer Science, 2018 The language Eff is an OCaml-like language serving as a prototype implementation of the theory of algebraic effects, intended for experimentation with algebraic effects on a large scale.
Oleg Kiselyov, KC Sivaramakrishnan
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source