Results 1 to 10 of about 1,239,526 (390)

The effects of chemical and physical factors on mammalian embryo culture and their importance for the practice of assisted human reproduction.

Human Reproduction Update, 2016
BACKGROUND Although laboratory procedures, along with culture media formulations, have improved over the past two decades, the issue remains that human IVF is performed in vitro (literally 'in glass').
P. Wale, D. Gardner
semanticscholar   +1 more source

Transcriptional defects and reprogramming barriers in somatic cell nuclear reprogramming as revealed by single-embryo RNA sequencing

BMC Genomics, 2018
Background Nuclear reprogramming reinstates totipotency or pluripotency in somatic cells by changing their gene transcription profile. This technology is widely used in medicine, animal husbandry and other industries.
Yong Liu, Fengrui Wu, Ling Zhang, Xiaoqing Wu, Dengkun Li, Jing Xin, Juan Xie, Feng Kong, Wenying Wang, Qiaoqin Wu, Di Zhang, Rong Wang, Shaorong Gao, Wenyong Li   +13 more
doaj   +1 more source

Immunogenicity evaluation of inactivated virus and purified proteins of porcine circovirus type 2 in mice

BMC Veterinary Research, 2018
Background Vaccination is considered as an effective and economical way to against PCV2 infection. However, some of commercial available vaccines are based on inactivated viruses, while the others are based on purified protein of PCV2.
Xiaohui Liu, Ting Ouyang, Teng Ma, Hongsheng Ouyang, Daxin Pang, Linzhu Ren   +5 more
doaj   +1 more source

Identification of key factors conquering developmental arrest of somatic cell cloned embryos by combining embryo biopsy and single-cell sequencing

Cell Discovery, 2016
Differentiated somatic cells can be reprogrammed into totipotent embryos through somatic cell nuclear transfer. However, most cloned embryos arrest at early stages and the underlying molecular mechanism remains largely unexplored.
Wenqiang Liu, Xiaoyu Liu, Chenfei Wang, Yawei Gao, Rui Gao, X. Kou, Yanhong Zhao, Jingyi Li, You Wu, Wenchao Xiu, Su Wang, Jiqing Yin, W. Liu, T. Cai, Hong Wang, Yong Zhang, Shaorong Gao   +16 more
semanticscholar   +1 more source

Role of microRNAs in embryo implantation

Reproductive Biology and Endocrinology, 2017
Failure of embryo implantation is a major limiting factor in early pregnancy and assisted reproduction. Determinants of implantation include the embryo viability, the endometrial receptivity, and embryo-maternal interactions.
Jingjie Liang, Shaoyu Wang, Zhengguang Wang   +2 more
semanticscholar   +1 more source

MBNL1 Suppressed Cancer Metastatic of Skin Squamous Cell Carcinoma Via by TIAL1/MYOD1/Caspase-9/3 Signaling Pathways

Technology in Cancer Research & Treatment, 2021
Objective: The incidence of skin squamous cell carcinoma (SSCC) has recently been increasing, with diverse clinical manifestations.SSCC could metastasize to lymph nodes or other organs, posing a great threat to life.
Jiaorong Chen, Jiaqi Wang, Jingyi Qian, Mengying Bao, Xin Zhang, Zheng Huang   +5 more
doaj   +1 more source

The decidua—the maternal bed embracing the embryo—maintains the pregnancy

Seminars in Immunopathology, 2016
The decidua has been known as maternal uterine tissue, which plays essential roles in protecting the embryo from being attacked by maternal immune cells and provides nutritional support for the developing embryo prior to placenta formation.
M. Mori, Á. Bogdán, T. Balassa, T. Csabai, J. Szekeres-Bartho   +4 more
semanticscholar   +1 more source

Expression of factors involved in apoptosis and cell survival is correlated with enzymes synthesizing lysophosphatidic acid and its receptors in granulosa cells originating from different types of bovine ovarian follicles

Reproductive Biology and Endocrinology, 2017
Background Lysophosphatidic acid (LPA) regulates reproductive processes in the cow. Ovarian granulosa cells play a pivotal role in follicle growth and development.
Emilia Sinderewicz, Katarzyna Grycmacher, Dorota Boruszewska, Ilona Kowalczyk-Zięba, Joanna Staszkiewicz, Tomasz Ślężak, Izabela Woclawek-Potocka   +6 more
doaj   +1 more source

Assessment of human embryo development using morphological criteria in an era of time-lapse, algorithms and 'OMICS': is looking good still important?

Molecular human reproduction, 2016
With the worldwide move towards single embryo transfer there has been a renewed focus on the requirement for reliable means of assessing embryo viability. In an era of 'OMICS' technologies, and algorithms created through the use of time-lapse microscopy,
D. Gardner, B. Balaban
semanticscholar   +1 more source

Minimally Invasive Embryo Transfer and Embryo Vitrification at the Optimal Embryo Stage in Rabbit Model [PDF]

Journal of Visualized Experiments, 2019
Assisted reproductive techniques (ARTs), such as in vitro embryo culture or embryo cryopreservation, affect natural development patterns with perinatal and postnatal consequences. To ensure the innocuousness of ART applications, studies in animal models are necessary.
Garcia-Dominguez, X, Marco-Jiménez, Francisco, Viudes de Castro, María Pilar, Vicente Antón, José Salvador   +3 more
openaire   +2 more sources