Results 1 to 10 of about 452,413 (312)

Embryo Genetics [PDF]

open access: yesGenes, 2021
Advances in embryo and reproductive genetics have influenced clinical approaches to overcome infertility. Since the 1990s, many attempts have been made to decipher the genetic causes of infertility and to understand the role of chromosome aneuploidies in embryo potential.
Carmen Rubio, Carlos Simón
openaire   +2 more sources

The Novel Competing Endogenous Long Noncoding RNA SM2 Regulates Gonadotropin Secretion in the Hu Sheep Anterior Pituitary by Targeting the Oar-miR-16b/TGF-β/SMAD2 Signaling Pathway

open access: yesCells, 2022
Pituitary gonadotropins play a pivotal role in reproduction. Long noncoding RNAs (lncRNAs) have been identified as important regulators in the hypothalamic–pituitary–ovarian (HPO) axis associated with reproduction.
Zhen Wan   +7 more
doaj   +1 more source

Knockdown of KDM5B Leads to DNA Damage and Cell Cycle Arrest in Granulosa Cells via MTF1

open access: yesCurrent Issues in Molecular Biology, 2023
KDM5B is essential for early embryo development, which is under the control of maternal factors in oocytes. Granulosa cells (GCs) play a critical role during oocyte mature. However, the role of KDM5B in GCs remains to be elucidated. In the current study,
Yingnan Yang   +7 more
doaj   +1 more source

Cumulative live birth rates between GnRH-agonist long and GnRH-antagonist protocol in one ART cycle when all embryos transferred: real-word data of 18,853 women from China

open access: yesReproductive Biology and Endocrinology, 2021
Background A consensus has been reached on the preferred primary outcome of all infertility treatment trials, which is the cumulative live birth rate (CLBR).
Jingwei Yang   +5 more
doaj   +1 more source

The transverse diameter of right common femoral vein by ultrasound in the supine position for predicting post-spinal hypotension during cesarean delivery

open access: yesBMC Anesthesiology, 2021
Background Post-spinal anesthesia hypotension during cesarean delivery is caused by decreased systemic vascular resistance due to the blockage of the autonomic nerves, which is further worsened by inferior vena cava (IVC) compression by the gravid uterus.
Shi-Fa Yao   +6 more
doaj   +1 more source

Engineered domain-inlaid Nme2Cas9 adenine base editors with increased on-target DNA editing and targeting scope

open access: yesBMC Biology, 2023
Background Nme2ABE8e has been constructed and characterized as a compact, accurate adenine base editor with a less restrictive dinucleotide protospacer-adjacent motif (PAM: N4CC) but low editing efficiency at challenging loci in human cells.
Ding Zhao   +11 more
doaj   +1 more source

The Genetic Mutation of ANO5 in Rabbits Recapitulates Human Cardiomyopathy

open access: yesApplied Sciences, 2020
The limb girdle muscular dystrophy type 2L (LGMD2L) is caused by mutations of the ANO5 gene in humans which encodes a 913 amino-acid integral membrane protein.
Tingting Sui   +5 more
doaj   +1 more source

A Study on Genes of Bayanbulak Sheep [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2013
The average twin lambing rate of Bayanbulak sheep is 2% to 3%. However, a flock of sheep with a close genetic relationship and an average of 2 to 3 lambs per birth has been found recently.
Beiyao Zuo   +10 more
doaj   +1 more source

Embryo–Endosperm Interactions [PDF]

open access: yesAnnual Review of Plant Biology, 2022
In angiosperms, double fertilization triggers the concomitant development of two closely juxtaposed tissues, the embryo and the endosperm. Successful seed development and germination require constant interactions between these tissues, which occur across their common interface. The embryo–endosperm interface is a complex and poorly understood compound
Ingram, Gwyneth, Doll, Nicolas
openaire   +4 more sources

Maternal Magnolol Supplementation during Pregnancy and Lactation Promotes Antioxidant Capacity, Improves Gut Health, and Alters Gut Microbiota and Metabolites of Weanling Piglets

open access: yesMetabolites, 2023
Maternal nutrition exerts a profound effect on the postnatal performance of offspring, especially during the weaning period. The multifunctional bioactive component magnolol (MAG) has shown promise as a dietary supplement. This study aimed to explore the
Qiwen Fan   +8 more
doaj   +1 more source

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