Results 1 to 10 of about 169 (168)
Genes, 2021 Advances in embryo and reproductive genetics have influenced clinical approaches to overcome infertility. Since the 1990s, many attempts have been made to decipher the genetic causes of infertility and to understand the role of chromosome aneuploidies in embryo potential.
Carmen Rubio, Carlos Simón
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Developmental Biology, 2000 A lesson learned from modern developmental biology is the striking degree of conservation of strategies and molecules used to program developmental events in species as diverse as insects, birds, amphibians, and mammals. Nonetheless, mammals retain distinctions with regard to the strategies used to protect and nourish their offspring during development,
Carson, Daniel D. +6 more
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Proceedings of the National Academy of Sciences, 2011 Generation of transgenic mice by pronuclear DNA injection into fertilized eggs has been well-established for over 30 y (1). However, it remains a rather crude approach: injected sequences randomly insert as concatamers, they can be mutagenic, and they have variable expression depending on the site of integration, a phenomenon called position effects ...
Janet Rossant +2 more
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The Embryo Sac and Embryo of Striga lutea [PDF]
Botanical Gazette, 1915 1. Striga lutea is a semi-parasitic annual belonging to the Rhinantheae-Gerardieae group of the Scrophulariaceae. 2. The ovary is of the ordinary bilocular scrophulariaceous type, and the ovules are anatropous, with one integument. 3. The megaspore mother cell arises directly from a single subepidermal cell, which gives rise to a row of four megaspores,
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Immunolabeling of Embryos [PDF]
, 2008 The molecular mechanisms controlling Drosophila embryogenesis are among the best-studied examples in animal development. Whereas the formation of developmental pattern in embryos was intensely examined in the past three decades, the cell biological basis of morphogenesis is now entering the center stage of the research on fly embryos.
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Embryo Sac and Embryo of Phaseolus
Botanical Gazette, 1918 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
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FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
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ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
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FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
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[Chimeric embryos and pseudo-embryos: An alternative to human embryos for research].
Medecine sciences : M/S, 2021 L’étude du développement humain est indispensable afin d’approfondir nos connaissances et, à long terme, perfectionner nos stratégies thérapeutiques dans les domaines de la médecine de la reproduction et de la médecine régénératrice. Face à la limite d’accès aux embryons surnuméraires et à l’interdiction d’en créer de nouveaux seulement à des fins de ...
Savatier, Pierre +5 more
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