Results 161 to 170 of about 536,166 (300)

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Epigenetic blind spots - the role of DNA methylation dynamics in stem cell-based models of embryogenesis. [PDF]

FEBS Lett
Canil S, Corrà A, Scapolatiello A, Qiu C, Amadei G.   +4 more
europepmc   +1 more source

Micromanipulation of mammalian embryos.

The Journal of toxicological sciences, 1989
Micromanipulation of embryos provide a new and valuable biological tool for animal agriculture and medical fields. Current techniques for embryo manipulation are in practice but some of techniques is still way off for application. The present status in new biotechnology applying to animal science and medicine is reviewed and its future is also ...
openaire   +1 more source

Micro/Nanoscale Acoustic Manipulation: From Particle Control to Autonomous Microswimmers

Advanced Science, EarlyView.
This conceptual framework illustrates acoustic technology as a multifunctional platform enabling passive particle manipulation across scales and autonomous propulsion of microswimmers. ABSTRACT Acoustic manipulation and propulsion technologies have emerged as powerful platforms for micro/nanoscale control, enabled by their non‐contact operation, label ...
Jiahui Chu, Lemin Zhang, Xu Wang, Wenzong Li, Yahua Liu   +4 more
wiley   +1 more source

DNA methylation reprogramming in marsupial embryos is restricted to the extraembryonic lineage. [PDF]

Nat Commun
Angeloni A, Hammond JM, Peters TJ, Reis ALM, Kemp L, Amos TG, Gamaarachchi H, Humphries S, Wilmott LA, Pal S, Masamsetti VP, Weatherstone M, Ip CK, Pazaky K, Steel A, Lyons R, Walters ED, Liu N, Tam P, Polo JM, Waters PD, Clark SJ, Richards LJ, Smith AD, Lee HJ, Deveson IW, Griffith OW, Skvortsova K.   +27 more
europepmc   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

From Static to Dynamic: Fluorescence Imaging Technology Advances Precise Embryo Evaluation. [PDF]

Small Methods
Wu J, Li Y, Wang Q, Wang T, Li K, Lou X, Dai J.   +6 more
europepmc   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

The vertebrate yolk sac: evolutionary origins and current advances in in vitro models. [PDF]

Development
Blagrove JR, Orsi AER, Cindrova-Davies T, Niakan KK.   +3 more
europepmc   +1 more source

Experiments on Mammalian Embryos [PDF]

Nature, 1936
openaire   +1 more source