Results 191 to 200 of about 206,297 (286)
Silver nanoparticles (AgNPs) synthesized using eco‐friendly green synthesis approaches exhibit remarkable antimicrobial activity and enhanced drug delivery potential. Polymer‐AgNPs conjugates further improve drug stability and targeted delivery, offering a multifunctional platform for biomedical applications.
Mukil Madhusudanan+6 more
wiley +1 more source
Potent Fluorescent Probe for Target‐Engagement Studies of Allosteric Pyruvate Kinase Modulators
LumiPK, a novel environment‐sensitive fluorescent tracer, enables direct monitoring of allosteric ligand engagement with pyruvate kinase fused with nanoluciferase (Nluc), focusing on the liver isoform (PKL). In NanoBRET, and fluorescence indicator displacement assays, LumiPK shows high affinity and validates known allosteric modulators of PKL.
Oscar Nilsson+9 more
wiley +2 more sources
Perturbing nuclear glycosylation in the mouse preimplantation embryo slows down embryonic development. [PDF]
Formichetti S+6 more
europepmc +1 more source
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo+2 more
wiley +1 more source
Embryo and prejudice: From diverse first transcriptional impressions to a common developmental path. [PDF]
Giraud Collet G, Festuccia N, Navarro P.
europepmc +1 more source
Nanoparticles Functionalized with Polymer Brushes for Gene Delivery
The engineering of the next generation gene delivery vectors requires the precise control of the architecture and physicochemical interactions controlling the transport, targeting, uptake, and release of nucleic acid materials to targeted cells. Polymer brush‐functionalized nanomaterials offer unprecedented control over such design and properties, and ...
Carlos E. Neri‐Cruz, Julien E. Gautrot
wiley +1 more source
Pluripotency genes of mammals: a network at work. [PDF]
Cancedda R, Mastrogiacomo M.
europepmc +1 more source
Emerging Frontiers in Zebrafish Embryonic and Adult-Derived Cell Lines. [PDF]
Arana ÁJ+3 more
europepmc +1 more source
Lipid in Mammalian Embryo Development.
Hirotada Tsujii+2 more
openaire +3 more sources
Methodological and Ethical Considerations in the Use of Chordate Embryos in Biomedical Research. [PDF]
Campitelli LMM+14 more
europepmc +1 more source