Results 201 to 210 of about 209,877 (288)

Hypothesis: Ephrin–Eph Signaling Pathways Provide Novel Targets for Accelerated Re‐Epithelialization of Cutaneous Wounds

BioEssays, EarlyView.
In distal limb wounds on the horse, the proliferative phase of repair often produces excessive granulation tissue that delays healing by impeding keratinocyte migration from wound margins. This essay examines the basis for the hypothesis that ephrin–Eph signaling pathways that stimulate keratinocyte migration provide novel targets for re‐establishing ...
Rodolfo D. Vicetti Miguel, Mohan Liu, Gabriel J. Campion, Thomas L. Cherpes   +3 more
wiley   +1 more source

Fetal growth and congenital heart disease at high altitude. [PDF]

Philos Trans R Soc Lond B Biol Sci
Giussani DA.
europepmc   +1 more source

Where, When, and How? Integrating Spatiotemporal Cues in Cell Division

BioEssays, EarlyView.
Accurate chromosome segregation during mitosis depends on the spatial and temporal regulation of spindle assembly, kinetochore‐microtubule attachment, and checkpoint signaling. Here, we highlight how mitotic chromosomes can serve as dynamic hubs that integrate molecular cues to coordinate spindle organization and timing, ensuring faithful genome ...
Luca Cirillo, Hradini Konthalapalli, Claudio Alfieri, Jonathon Pines   +3 more
wiley   +1 more source

Maturation of GABAergic signalling times the opening of a critical period in Drosophila melanogaster. [PDF]

Sci Rep
Corke J, Radi MH, Landgraf M, Baines RA.
europepmc   +1 more source

Comparative Analysis of HEK293 Genomic Variability

Biotechnology and Bioengineering, EarlyView.
An investigation of how HEK293‐derived cell lines adapt genetically to different culture conditions and environmental pressures: despite distinct phenotypes and cultivation histories, comparative whole‐genome analyses of established HEK293 variants as well as newly suspension‐adapted cells revealed a shared, common set of mutations linked to cell ...
Georg Smesnik, Nikolaus Virgolini, Maria Toth, Astrid Dürauer, Nicole Borth   +4 more
wiley   +1 more source

Embryonic Circadian Rhythm Establishment, Homeostasis, and Dysfunction During Organogenesis. [PDF]

Stem Cells Int
Chen SL, Zhou H, Li YM, Zheng YW.
europepmc   +1 more source

Bottom‐Up Ice Growth Geometry Attenuates Shear Stress and Improves the Cryopreservation of Hematopoietic Stem/Progenitor Cells Under Low DMSO Concentrations

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Studies on cell cryopreservation have been limited by the complexity of the freezing process and challenges on controlling ice formation, managing cooling rates, and optimizing cryoprotectant concentrations. The objective of this study is to evaluate the impact of bottom‐up and conventional radial freezing on the viability of mammalian cells ...
Rafaela Ouro Neves, Pedro Sena Rego, Marta H. G. Costa, Isabel Bogalho, Andreia Duarte, Claúdia L. da Silva, Frederico Castelo Ferreira, Vitor Geraldes, Miguel A. Rodrigues   +8 more
wiley   +1 more source

Peculiarities of the mammalian oocyte cell cycle. [PDF]

Physiology (Bethesda)
Wetherall B, Madgwick S.
europepmc   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Molecular factors driving the development of bovine embryos and embryo-like structures. [PDF]

Anim Reprod
Jiang Z.
europepmc   +1 more source