Results 51 to 60 of about 199,433 (310)
Trophoblast lineage specification in the mammalian preimplantation embryo
Reproductive Medicine and Biology, 2020 Background The establishment of the trophectoderm (TE) and the inner cell mass (ICM) is the first cell lineage segregation that occurs in mammalian preimplantation development. TE will contribute to the placenta while ICM cells give rise to the epiblast (
Yayoi Toyooka
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Primitive erythropoiesis in the mammalian embryo
The International Journal of Developmental Biology, 2010 Erythropoiesis in adult mammals is characterized by the progressive maturation of hematopoietic stem cells to lineage-specific progenitors, to morphologically identifiable precursors which enucleate to form mature erythrocytes. In contrast, primitive erythropoiesis is characterized by the appearance within the yolk sac of a transient, lineage ...
Jeffrey Malik +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
In Vitro Host-Cell Susceptibility to Usutu Virus
Emerging Infectious Diseases, 2005 We investigated the susceptibility to Usutu virus (Flavivirus) of 13 permanent cell lines, 3 primary cell cultures, and chicken embryos. Vero, PK-15, and goose embryo fibroblast cells developed cytopathic effects; however, viral multiplication was ...
Tamás Bakonyi +4 more
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Effects of mammalian sex hormones on in vitro organogenesis of common bean (Phaseolus vulgaris L.)
Scientific Reports, 2023 Beans are an important plant species and are one of the most consumed legumes in human nutrition, especially as a protein, vitamin, mineral, and fiber source.
Kamil Haliloğlu +5 more
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SL-07 Competency of Diploid Parthenogenesis Embryonic Stem Cell (pESC) for Cell Therapy [PDF]
, 2017 Naturally, mammalian embryo resulting from the fertilized oocytes by sperm and develops to the zygote with diploid chromosome. Through the embryo engineering, mammalian embryo also could be produce by: nuclear transfer and parthenogenesis. Embryo produce
Boediono, Arief
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NaNog: A pluripotency homeobox (master) molecule. [PDF]
, 2015 One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE +4 more
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A Tale of Division and Polarization in the Mammalian Embryo [PDF]
Developmental Cell, 2017 The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues (2017) show that the interplay between cell polarization and cell-cell contact drives the segregation of these lineages, providing a framework for self ...
Srinivas, S, Rodriguez, TA
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Development and validation of deep learning based embryo selection across multiple days of transfer [PDF]
arXiv, 2022 This work describes the development and validation of a fully automated deep learning model, iDAScore v2.0, for the evaluation of embryos incubated for 2, 3, and 5 or more days. The model is trained and evaluated on an extensive and diverse dataset including 181,428 embryos from 22 IVF clinics across the world.
arxiv
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source